Nicotinamide (niacinamide) Induces Liver Regeneration & Improves Liver Function By Activating SIRT1

[Dobster]

I typically take 1,000mgs daily, in divided dosages. Typically taken in 250mgs dosages throughout the day. Anything under 1.5 grams daily is safe. I think Haidut said in an interview that anything over 3 grams will negatively impact liver function.

Sorry is this the flush type or flush free ? Thank you

 

[Dobster]

I typically take 1,000mgs daily, in divided dosages. Typically taken in 250mgs dosages throughout the day. Anything under 1.5 grams daily is safe. I think Haidut said in an inte.rview that anything over 3 grams will negatively impact liver function.

 

[LeeLemonoil]

I‘d recommend everybody that plane to supp with B3 to read the info provided in this thread:

The Plasma NAD+ Metabolome Is Dysregulated In ‘‘Normal’’ Aging

It’s a powerful and tricky modulator of that crucial energy-switch, b3 is.
It’s potentially harmful if supped to high, too long, in age and so forth

 

[TeaRex14]

Sorry is this the flush type or flush free ? Thank you

Niacinamide, the no flush kind. I normally just take it with a meal.

 

[Dobster]

I‘d recommend everybody that plane to supp with B3 to read the info provided in this thread:

The Plasma NAD+ Metabolome Is Dysregulated In ‘‘Normal’’ Aging

It’s a powerful and tricky modulator of that crucial energy-switch, b3 is.
It’s potentially harmful if supped to high, too long, in age and so forth

Thank you..interesting read.

 

[Spondive]

Ok interesting. I have fatty liver and hope to clear it with this.

I have fatty liver with elevated liver enzymes which enzymes are now in normal range after taking vitamin E succinate 800 iu a day.. it took one month to normalize enzymes and my ultrasound of liver reduced in size and less fatty liver

 

[Dobster]

I have fatty liver with elevated liver enzymes which enzymes are now in normal range after taking vitamin E succinate 800 iu a day.. it took one month to normalize enzymes and my ultrasound of liver reduced in size and less fatty liver

Thank you - I take Vit E too but not daily, it has the 4 tocopherols in them, is succinate a better alternative?

 

[Spondive]

Thank you - I take Vit E too but not daily, it has the 4 tocopherols in them, is succinate a better alternative?

I tried those versions and didn’t have that effect so I think the succinate must be good in combination with the dry alpha tocopherol. Maybe it helps get it into the cells or maybe there are contaminants in the other forms of vitaminE , I don’t know?

 

[Frankdee20]

I don’t notice much besides increased hunger. I agree with @olive I like taking it with coffee in the morning.

You have to take it with alot of food, preferably carbs or sugar. Once there is adequate sugars, it has a nice energizing effect. I do not know how people take a gram or 2.

 

[Alex Jaramillo]

You have to take it with alot of food, preferably carbs or sugar. Once there is adequate sugars, it has a nice energizing effect. I do not know how people take a gram or 2.

Yes it works much better this way. Big breakfast/coffee/500 mg’s niacinamide

 

[Dobster]

I tried those versions and didn’t have that effect so I think the succinate must be good in combination with the dry alpha tocopherol. Maybe it helps get it into the cells or maybe there are contaminants in the other forms of vitaminE , I don’t know?

Ok noted. Will Try that next time.

 

[Dobster]

You have to take it with alot of food, preferably carbs or sugar. Once there is adequate sugars, it has a nice energizing effect. I do not know how people take a gram or 2.

Interesting. Thanks

 

[Frankdee20]

Interesting. Thanks

Well that is because it will burn through your sugar reserves. When that happens, you get hypoglycemic headaches.

 

[Dobster]

Well that is because it will burn through your sugar reserves. When that happens, you get hypoglycemic headaches.

Which I believe I get occasionaly

 

[Dobster]

Just to ask on the topic of liver regeneration - LIV52, has anyone used it and/or seen benefits from it ? Thanks

 

[olive]

Just to ask on the topic of liver regeneration - LIV52, has anyone used it and/or seen benefits from it ? Thanks

Useless. Take 200-600mg UDCA/TUDCA for 4 weeks if you really want to heal the liver, nothing comes close to it’s efficiency. Do not drink alcohol or consume hepatoxic substances while running the course. Be sure to consume sufficient choline and vitamin E so the liver can actually function and repair.

 

[A.R]

Nicotinamide induces liver regeneration and improves liver function by activating SIRT1.
Nicotinamide induces liver regeneration and improves liver function by activating SIRT1

“... The present study demonstrated that Nam regulated the process of liver regeneration and improved liver function by activating SIRT1“

Whilst I can't argue with the research,
I wonder why whenever I consume niacinamide I get a lot of pain in the liver area.

 

[olive]

Whilst I can't argue with the research,
I wonder why whenever I consume niacinamide I get a lot of pain in the liver area.

Insufficient choline/methionine?

 

[A.R]

Insufficient choline/methionine?

I've started drinking couple of raw eggs daily recently, so hopefully that should help

 

[Alex Jaramillo]

Useless. Take 200-600mg UDCA/TUDCA for 4 weeks if you really want to heal the liver, nothing comes close to it’s efficiency. Do not drink alcohol or consume hepatoxic substances while running the course. Be sure to consume sufficient choline and vitamin E so the liver can actually function and repair.

Did you test liver enzymes before and after or have you just noticed signs of better liver function?