Nicotinamide (aka niacinamide) may be a potent promoter of aging. Please see #5 in the following article which also mentions other issues with niacinamide. http://www.anti-agingfirewalls.com/...ging-framework-for-health-and-life-extension/ http://www.anti-agingfirewalls.com/...ging-framework-for-health-and-life-extension/