My 51 year old brother's blood work

[TacoVampire]

Hi all,

His TSH is above 1 and he has very low vitamin D. Also he has lost a bunch of weight in the past THREE years.. Any insights would be appreciated. Thanks!

<><>
CHOLESTEROL, TOTAL 174 Reference Range: <200 mg/dL

HDL CHOLESTEROL 60 Reference Range: > OR = 40 mg/dL

TRIGLYCERIDES 62 Reference Range: <150 mg/dL

LDL-CHOLESTEROL 100 H mg/dL (calc)

CHOL/HDLC RATIO 2.9 Reference Range: <5.0 (calc)

NON HDL CHOLESTEROL 114 Reference Range: <130 mg/dL (calc)

VITAMIN D,25-OH,TOTAL,IA 27 L Reference Range: 30-100 ng/mL

GLUCOSE 96 Reference Range: 65-99 mg/dL

UREA NITROGEN (BUN) 15 Reference Range: 7-25 mg/dL

CREATININE 0.77 Reference Range: 0.70-1.33 mg/dL

eGFR NON-AFR. AMERICAN 105 Reference Range: > OR = 60 mL/min/1.73m2

eGFR AFRICAN AMERICAN 122 Reference Range: > OR = 60 mL/min/1.73m2

BUN/CREATININE RATIO NOT APPLICABLE Reference Range: 6-22 (calc)

SODIUM 139 Reference Range: 135-146 mmol/L

POTASSIUM 4.5 Reference Range: 3.5-5.3 mmol/L

CHLORIDE 102 Reference Range: 98-110 mmol/L

CARBON DIOXIDE 31 Reference Range: 20-32 mmol/L

CALCIUM 9.8 Reference Range: 8.6-10.3 mg/dL

PROTEIN, TOTAL 7.6 Reference Range: 6.1-8.1 g/dL

ALBUMIN 4.6 Reference Range: 3.6-5.1 g/dL

GLOBULIN 3.0 Reference Range: 1.9-3.7 g/dL (calc)

ALBUMIN/GLOBULIN RATIO 1.5 Reference Range: 1.0-2.5 (calc)

BILIRUBIN, TOTAL 0.5 Reference Range: 0.2-1.2 mg/dL

ALKALINE PHOSPHATASE 68 Reference Range: 35-144 U/L

AST 22 Reference Range: 10-35 U/L

ALT 21 Reference Range: 9-46 U/L

HEMOGLOBIN A1c 5.3 Reference Range: <5.7 % of total Hgb

TSH 1.42 Reference Range: 0.40-4.50 mIU/L

WHITE BLOOD CELL COUNT 6.1 Reference Range: 3.8-10.8 Thousand/uL

RED BLOOD CELL COUNT 5.01 Reference Range: 4.20-5.80 Million/uL

HEMOGLOBIN 14.5 Reference Range: 13.2-17.1 g/dL

HEMATOCRIT 44.1 Reference Range: 38.5-50.0 %

MCV 88.0 Reference Range: 80.0-100.0 fL

MCH 28.9 Reference Range: 27.0-33.0 pg

MCHC 32.9 Reference Range: 32.0-36.0 g/dL

RDW 12.8 Reference Range: 11.0-15.0 %

PLATELET COUNT 259 Reference Range: 140-400 Thousand/uL

MPV 9.5 Reference Range: 7.5-12.5 fL

ABSOLUTE NEUTROPHILS 3068 Reference Range: 1500-7800 cells/uL

ABSOLUTE LYMPHOCYTES 2214 Reference Range: 850-3900 cells/uL

ABSOLUTE MONOCYTES 451 Reference Range: 200-950 cells/uL

ABSOLUTE EOSINOPHILS 293 Reference Range: 15-500 cells/uL

ABSOLUTE BASOPHILS 73 Reference Range: 0-200 cells/uL

NEUTROPHILS 50.3 %

LYMPHOCYTES 36.3 %

MONOCYTES 7.4 %

EOSINOPHILS 4.8 %

BASOPHILS 1.2 %

URINALYSIS, COMPLETE

COLOR YELLOW Reference Range: YELLOW

APPEARANCE CLEAR Reference Range: CLEAR

SPECIFIC GRAVITY 1.016 Reference Range: 1.001-1.035

PH 6.5 Reference Range: 5.0-8.0

GLUCOSE NEGATIVE Reference Range: NEGATIVE

BILIRUBIN NEGATIVE Reference Range: NEGATIVE

KETONES NEGATIVE Reference Range: NEGATIVE

OCCULT BLOOD NEGATIVE Reference Range: NEGATIVE

PROTEIN NEGATIVE Reference Range: NEGATIVE

NITRITE NEGATIVE Reference Range: NEGATIVE

LEUKOCYTE ESTERASE NEGATIVE Reference Range: NEGATIVE

WBC NONE SEEN Reference Range: < OR = 5 /HPF

RBC NONE SEEN Reference Range: < OR = 2 /HPF

SQUAMOUS EPITHELIAL CELLS NONE SEEN Reference Range: < OR = 5 /HPF

BACTERIA NONE SEEN Reference Range: NONE SEEN /HPF

HYALINE CAST NONE SEEN Reference Range: NONE SEEN /LPF

IRON, TOTAL 91 Reference Range: 50-180 mcg/dL

FERRITIN 48 Reference Range: 38-380 ng/mL

VITAMIN B12 416 Reference Range: 200-1100 pg/mL

PROLACTIN 3.6 Reference Range: 2.0-18.0 ng/mL

TESTOSTERONE, TOTAL, MALES (ADULT), IA 558 Reference Range: 250-827 ng/dL

PSA, TOTAL 0.91 Reference Range: < OR = 4.00 ng/mL

 

[Chophouse360]

Hi all,

His TSH is above 1 and he has very low vitamin D. Also he has lost a bunch of weight in the past THREE years.. Any insights would be appreciated. Thanks!

<><>
CHOLESTEROL, TOTAL 174 Reference Range: <200 mg/dL

HDL CHOLESTEROL 60 Reference Range: > OR = 40 mg/dL

TRIGLYCERIDES 62 Reference Range: <150 mg/dL

LDL-CHOLESTEROL 100 H mg/dL (calc)

CHOL/HDLC RATIO 2.9 Reference Range: <5.0 (calc)

NON HDL CHOLESTEROL 114 Reference Range: <130 mg/dL (calc)

VITAMIN D,25-OH,TOTAL,IA 27 L Reference Range: 30-100 ng/mL

GLUCOSE 96 Reference Range: 65-99 mg/dL

UREA NITROGEN (BUN) 15 Reference Range: 7-25 mg/dL

CREATININE 0.77 Reference Range: 0.70-1.33 mg/dL

eGFR NON-AFR. AMERICAN 105 Reference Range: > OR = 60 mL/min/1.73m2

eGFR AFRICAN AMERICAN 122 Reference Range: > OR = 60 mL/min/1.73m2

BUN/CREATININE RATIO NOT APPLICABLE Reference Range: 6-22 (calc)

SODIUM 139 Reference Range: 135-146 mmol/L

POTASSIUM 4.5 Reference Range: 3.5-5.3 mmol/L

CHLORIDE 102 Reference Range: 98-110 mmol/L

CARBON DIOXIDE 31 Reference Range: 20-32 mmol/L

CALCIUM 9.8 Reference Range: 8.6-10.3 mg/dL

PROTEIN, TOTAL 7.6 Reference Range: 6.1-8.1 g/dL

ALBUMIN 4.6 Reference Range: 3.6-5.1 g/dL

GLOBULIN 3.0 Reference Range: 1.9-3.7 g/dL (calc)

ALBUMIN/GLOBULIN RATIO 1.5 Reference Range: 1.0-2.5 (calc)

BILIRUBIN, TOTAL 0.5 Reference Range: 0.2-1.2 mg/dL

ALKALINE PHOSPHATASE 68 Reference Range: 35-144 U/L

AST 22 Reference Range: 10-35 U/L

ALT 21 Reference Range: 9-46 U/L

HEMOGLOBIN A1c 5.3 Reference Range: <5.7 % of total Hgb

TSH 1.42 Reference Range: 0.40-4.50 mIU/L

WHITE BLOOD CELL COUNT 6.1 Reference Range: 3.8-10.8 Thousand/uL

RED BLOOD CELL COUNT 5.01 Reference Range: 4.20-5.80 Million/uL

HEMOGLOBIN 14.5 Reference Range: 13.2-17.1 g/dL

HEMATOCRIT 44.1 Reference Range: 38.5-50.0 %

MCV 88.0 Reference Range: 80.0-100.0 fL

MCH 28.9 Reference Range: 27.0-33.0 pg

MCHC 32.9 Reference Range: 32.0-36.0 g/dL

RDW 12.8 Reference Range: 11.0-15.0 %

PLATELET COUNT 259 Reference Range: 140-400 Thousand/uL

MPV 9.5 Reference Range: 7.5-12.5 fL

ABSOLUTE NEUTROPHILS 3068 Reference Range: 1500-7800 cells/uL

ABSOLUTE LYMPHOCYTES 2214 Reference Range: 850-3900 cells/uL

ABSOLUTE MONOCYTES 451 Reference Range: 200-950 cells/uL

ABSOLUTE EOSINOPHILS 293 Reference Range: 15-500 cells/uL

ABSOLUTE BASOPHILS 73 Reference Range: 0-200 cells/uL

NEUTROPHILS 50.3 %

LYMPHOCYTES 36.3 %

MONOCYTES 7.4 %

EOSINOPHILS 4.8 %

BASOPHILS 1.2 %

URINALYSIS, COMPLETE

COLOR YELLOW Reference Range: YELLOW

APPEARANCE CLEAR Reference Range: CLEAR

SPECIFIC GRAVITY 1.016 Reference Range: 1.001-1.035

PH 6.5 Reference Range: 5.0-8.0

GLUCOSE NEGATIVE Reference Range: NEGATIVE

BILIRUBIN NEGATIVE Reference Range: NEGATIVE

KETONES NEGATIVE Reference Range: NEGATIVE

OCCULT BLOOD NEGATIVE Reference Range: NEGATIVE

PROTEIN NEGATIVE Reference Range: NEGATIVE

NITRITE NEGATIVE Reference Range: NEGATIVE

LEUKOCYTE ESTERASE NEGATIVE Reference Range: NEGATIVE

WBC NONE SEEN Reference Range: < OR = 5 /HPF

RBC NONE SEEN Reference Range: < OR = 2 /HPF

SQUAMOUS EPITHELIAL CELLS NONE SEEN Reference Range: < OR = 5 /HPF

BACTERIA NONE SEEN Reference Range: NONE SEEN /HPF

HYALINE CAST NONE SEEN Reference Range: NONE SEEN /LPF

IRON, TOTAL 91 Reference Range: 50-180 mcg/dL

FERRITIN 48 Reference Range: 38-380 ng/mL

VITAMIN B12 416 Reference Range: 200-1100 pg/mL

PROLACTIN 3.6 Reference Range: 2.0-18.0 ng/mL

TESTOSTERONE, TOTAL, MALES (ADULT), IA 558 Reference Range: 250-827 ng/dL

PSA, TOTAL 0.91 Reference Range: < OR = 4.00 ng/mL

I feel like those are really good

 

[yerrag]

His TSH is above 1 and he has very low vitamin D. Also he has lost a bunch of weight in the past THREE years.. Any insights would be appreciated. Thanks!

Did he lose weight intentionally or was he sickly? From fat to normal. Or from normal to sickly thin?

His blood markers look good.

Just a few to note: TSH can be lower to less than 1. He could be hypothyroid. What are his waking temps and at 5 pm? Other than the TSH, a thyroid panel consisting of T3 and T4 and rT3 would give a better picture, although I personally prefer an ECG that gives a QTc <= 440 msec to know there is no hypothyroid. Since expensive to see a cardiologist to get QTc, I would rather buy a personal ECG that costs around $100 and it can give you a reading as much as you want. The FL20 from Facelake is a unit I've been using and I'm happy with it.

The monocytes, eosinophils, and basophils are high. 7.4 vs 7% max, 4.8% vs 3% max, and 1.2% vs 1% max. I use functional medicine reference range as I do not trust the standard of care reference range, which is too lax. While the wbc count is well within range, these values could mean some parasites. But this is something conventional doctors will pooh pooh as nothing - until he gets sick.

His blood sugar, at 96, is high, I would prefer it between 80 and 85. If he has good blood sugar regulation, he should be able to go through a day of fasting without feeling much stress, hunger, or falling sick with sneezing, coughing, or developing a fever. The HbA1c says he's fine, but really the HbA1c is not a good marker of blood sugar health. Blood sugar health is about being able to maintain a blood sugar level within around 80-85 all throughout the day in between meals, or in a one day fast. A better test is a 5hr oral glucose tolerance test, but that service is no longer offered. Only 2 hr tests are offered, and it's practically useless. The only way out is to do your own 5hr OGTT.

 

[Blossom]

I think the overall picture from the labs looks pretty good too.

If he’s just coming out of the winter season then that could explain the lower vitamin D. He could increase that with sun light or explore supplements according to his preference.

I also wondered (like yerrag) if the weight loss was intentional and if he went from overweight to normal or from normal to underweight? Slow but steady weight loss from overweight or obese to normal is usually positive. Unintentionally losing from normal to underweight could be a problem.

Is he having specific complaints or does he feel good?

A little more context about his situation would certainly help people give input.

 

[Neeters 27]

I see his iron and iron stores are a bit low, this can make one tired and feel weak. Also, while his testosterone may be adequate, he might have high SHBG, which binds to his T and renders it unusable. so if he feels weak, losing muscle mass, losing hair etc, then this can be an issue, and unfortunately doctors dont even test for this, but a good functional med doc or naturopath will... is he on any meds, and how is he feeling? At age 51, its full blown Andropause, and the weight loss can be muscle wasting due to inadequate nutrition and of course, all our hormones wane and dwindle unless we do weight training, eat proteins, supplement, etc.

 

[Neeters 27]

I also wanted to add poor liver function will raise SHBG, if he drinks even moderately, liver as with all organs, work less efficiently with aging. liver function tests wont show red flags until DAMAGE is advanced...hope this all helps!