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From what i have seen from the studies, 3-beta-HSD is actually upregulated/overexpressed in balding scalps.I keep posting this in hairloss threads but I think it bears repeating. Pansterone applied on scrotum thickened my hair amazingly. My wife keeps commenting on the transformation. Haven't had scalp itch for weeks. This leads me to think a dysfunction of steroidogenic enzymes 3ahsd and 3bhsd is heavily implicated in hairloss. My 2c.
I ran across a study that claimed raspberry ketones promoted hair growth. The researchers thought it was raising IGF-1 in the skin where it was applied. Anyway, here is the link
Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elastici... - PubMed - NCBI
When applied topically to the scalp and facial skin, 0.01% RK promoted hair growth in 50.0% of humans with alopecia (n=10)
and apparently you can buy raspberry ketones in bulk...
Pure Raspberry Ketones Powder in Bulk | BulkSupplements.com
I think people use it for fat loss or something.
Do you have that study? There is A LOT of anecdotal evidence online about people experiencing hair loss from taking minocycline
When you say ethanol, are you using vodka or something?Yes, if I used castor oil only. If I cut it with 50% ethanol or 50% coconut oil it helps very much with any itch. Also, if I used castor only before bed I kept getting some pimples on my neck and hairline it was so annoying.
I keep posting this in hairloss threads but I think it bears repeating. Pansterone applied on scrotum thickened my hair amazingly. My wife keeps commenting on the transformation. Haven't had scalp itch for weeks. This leads me to think a dysfunction of steroidogenic enzymes 3ahsd and 3bhsd is heavily implicated in hairloss. My 2c.
When you say ethanol, are you using vodka or something?
Yes, ever clear
TubZy, anyone that you know of using the 2.5% selsun blue?
I can get it without script, just not sure if it's worth it over the 1% ?
What about lithium and taurine topically? Try to influence diodinase typ 2 and 3 enzymes. Type 3 is currently shown to increase RT3 and is expressed in hair follicles.(studies are dotted around the forum.)
Lithium inhibits them both,type 2 is good and increases conversion of t4 to t3 so applying taurine a few hours before and then lithium or apply lithium to halt type 3 and then applying taurine a few hours later to up regulate type 2 again.
Obviously type 3 enzyme has a purpose so goo to keep in mind before somebody discovers a suicide inhibitor.
Wild speculation but if you have nothing to loose......
Very cool, Soren.I don't know if anyone on this thread has mentioned scalp massage or more specifically dumutescenece therapy but I have been doing that for a number of months and have seen some encouraging progress.
@TubZy sure am ,TubZy, anyone that you know of using the 2.5% selsun blue?
I can get it without script, just not sure if it's worth it over the 1% ?
@TubZyTubZy, anyone that you know of using the 2.5% selsun blue?
I can get it without script, just not sure if it's worth it over the 1% ?
I would be interested, you have any studies on lithium? What is the best form and easy to dissolve, is it lithium orotate?
@TubZy sure am ,
@TubZy
i sure am , its beend a long time since ive used selsun blue.. but the gold makes my scalp feel very healthy with no itch
i think most people would be deterred by the smell but i quite like it.
atm i have also made my own topical formula...
It contains
Alpecin Caffeine Liquid
Niacinamide
P5P
R5P
Biotin
Vitamin E Acetate
T3
retinyl acetate
salicylic acid
Hydroxypropyl Starch Phosphate
@TubZy sure am ,
@TubZy
i sure am , its beend a long time since ive used selsun blue.. but the gold makes my scalp feel very healthy with no itch
i think most people would be deterred by the smell but i quite like it.
atm i have also made my own topical formula...
It contains
Alpecin Caffeine Liquid
Niacinamide
P5P
R5P
Biotin
Vitamin E Acetate
T3
retinyl acetate
salicylic acid
Hydroxypropyl Starch Phosphate