Mother cell sacrifices acidity to rejuvenate daughter cell

[Such_Saturation]

Mother-daughter asymmetry of pH underlies aging and rejuvenation in yeast

Note that "Pma1" makes the reduction in acidity happen and they used estradiol to make it happen even more.

Bonus:

<<We and others (53) note that repeated imaging differentially affected signal intensity captured at 402 and 490 nm excitation wavelengths, which altered the excitation ratios of sequential images in a pH-independent manner. Therefore we captured a single set of images per cell and never exposed cells to excitation wavelengths prior to pHluorin imaging.>>