https://www.sciencedaily.com/releases/2017/03/170323141403.htm
Saw this a few days ago, i am just the messenger here , want to know what the people here think about it.
Some random points -
-- "Johns Hopkins Kimmel Cancer Center scientists report data from a new study providing evidence that random, unpredictable DNA copying "mistakes" account for nearly two-thirds of the mutations that cause cancer. Their research is grounded on a novel mathematical model based on DNA sequencing and epidemiologic data from around the world"
-- "it is not as well-known that each time a normal cell divides and copies its DNA to produce two new cells, it makes multiple mistakes," says Cristian Tomasetti, Ph.D., assistant professor of biostatistics at the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins Bloomberg School of Public Health. "These copying mistakes are a potent source of cancer mutations that historically have been scientifically undervalued, and this new work provides the first estimate of the fraction of mutations caused by these mistakes."
-- "the scientists took a close look at the mutations that drive abnormal cell growth among 32 cancer types (Supplemental Materials, Table S6). They developed a new mathematical model using DNA sequencing data from The Cancer Genome Atlas and epidemiologic data from the Cancer Research UK database."
--"Looking across all 32 cancer types studied, the researchers estimate that 66 percent of cancer mutations result from copying errors, 29 percent can be attributed to lifestyle or environmental factors, and the remaining 5 percent are inherited"
--"Vogelstein says that people with cancer who have avoided known risk factors should be comforted by their findings. "It's not your fault," says Vogelstein. "Nothing you did or didn't do was responsible for your illness.""
Thoughts ?
Saw this a few days ago, i am just the messenger here , want to know what the people here think about it.
Some random points -
-- "Johns Hopkins Kimmel Cancer Center scientists report data from a new study providing evidence that random, unpredictable DNA copying "mistakes" account for nearly two-thirds of the mutations that cause cancer. Their research is grounded on a novel mathematical model based on DNA sequencing and epidemiologic data from around the world"
-- "it is not as well-known that each time a normal cell divides and copies its DNA to produce two new cells, it makes multiple mistakes," says Cristian Tomasetti, Ph.D., assistant professor of biostatistics at the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins Bloomberg School of Public Health. "These copying mistakes are a potent source of cancer mutations that historically have been scientifically undervalued, and this new work provides the first estimate of the fraction of mutations caused by these mistakes."
-- "the scientists took a close look at the mutations that drive abnormal cell growth among 32 cancer types (Supplemental Materials, Table S6). They developed a new mathematical model using DNA sequencing data from The Cancer Genome Atlas and epidemiologic data from the Cancer Research UK database."
--"Looking across all 32 cancer types studied, the researchers estimate that 66 percent of cancer mutations result from copying errors, 29 percent can be attributed to lifestyle or environmental factors, and the remaining 5 percent are inherited"
--"Vogelstein says that people with cancer who have avoided known risk factors should be comforted by their findings. "It's not your fault," says Vogelstein. "Nothing you did or didn't do was responsible for your illness.""
Thoughts ?