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More On Exemestane (Aromasin)

Discussion in 'Scientific Studies' started by LCohen, May 1, 2018.

  1. TreasureVibe

    TreasureVibe Member

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    Androsterone is almost identical to exemestane, but is a metabolite naturally occuring in the human body, while exemestane is a pharmaceutical drug.
     
  2. ecstatichamster

    ecstatichamster Member

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    I wonder if you've had the same results with androsterone?
     
  3. cyclops

    cyclops Member

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    By ground do you mean grinded very well into a powder? Is there benefit to this over just well cooked button mushrooms?
     
  4. ecstatichamster

    ecstatichamster Member

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    you have to grind them into little tiny pieces IMHO. Before or after cooking. The high surface area I think is beneficial. Big pieces can cause me indigestion.
     
  5. cyclops

    cyclops Member

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    Oh I see, its for the increased surface area. Makes sense.
     
  6. japanesedude

    japanesedude Member

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    i wonder why is nobody reports increase in T from Androsterone.
     
  7. RisingSun

    RisingSun Member

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    Because Exemestane and Androsterone are structurally related but not identical.
    The additional covalence bonds and hydrogen molecule in the structure of Exemestane gives it a bigger afinity to aromatase enzyme than androgen receptors.
     
  8. cyclops

    cyclops Member

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    Seems like Exemestane may be a better choice to Androsterone for men because you get both higher T and decreased E.
     
  9. Mauritio

    Mauritio Member

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    Agreed.
    With EXE you have the E and T -paths covered and if you add Preg/DHEA you might get more of the DHT conversion and generally more safety for the whole regimen. This is what I am doing right now.
    And I have to tell you: I tried 11-ketto, Andro and EXE . And EXE feels so much gentler , you can get away with much more. DHT does not feel so forgiving it feels kind of harsh on the body like it can go only one direction ,which is pretty much what it does. So far I really like EXE. It made me able to use more thyroid and for the first time I am able to use DHEA !

    I would really like to know how Andro would stack with EXE + preg + dhea... It might push this regimen more in the DHT direction and since Exe's aromatase inhibition isnt super strong in lower doses you might pretty good get away with it ...
     
  10. Mauritio

    Mauritio Member

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    Some people have even reported suppression of T from it. Which is to be expected since several people had these results from DHT (higher doses/ longer time period) and Andro converts to DHT so thats why Andro might be stacked nicely with Exemestane since it raises T even more so than it lowers Estrogen ,which Andro also takes care of.
     
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