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Minocycline black thyriod


Sep 26, 2019
Mar 10, 2021

Black thyroid?!!

“The patient received long-term, high dose antibiotics minocycline therapy (total dose: 70 g) for bronchial asthma associated with respiratory infection and died of uterine cancer. The thyroid gland was coal black in color and histological examination revealed numerous dark brown pigments scattered in the follicular epithelium and colloid matrix.”

“But, massive deposition of lipofuscin in the thyroid alone did not make the thyroid black and addition of minocycline appeared to be necessary for the black discoloration.”

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