Methylene Blue, Permanent Effects, Dependence, Taper Off Necessary?

[Logan-]

Does chronic use of methylene blue cause dependence in any way? After long term daily use of methylene blue, is tapering off necessary to stop taking it without experiencing any health issues?

Does chronic methylene blue usage permanently affect brain chemistry?

 

[Mauritio]

I would like to know too.
My guess would be no. And Haidut said that Oxidal and Lapodin are probably the best supps for long term use and systemic effect and probably dont need any breaks. MB does accumulate though, but the only thing that cauld be detrimental that comes to mind is to much MAO inhibition and thus too much serotonin esp. with eating cheese and Tyramine containing foods