Metabolic Clearance Rate Of Progesterone?

[domox]

I have read in several places that large meals increase the metabolic clearance rate of progesterone.
Can anybody explain the process?

Is it a result of high insulin or cortisol?...... Or.. Is it due to some other process?

I'm desperate to understand it but can't find any information on how that process works.

 

[paymanz]

Please link a reference.

 

[domox]

Anyone?

 

[lollipop]

The only fact I know about Progesterone and any form of "clearance" is that progesterone has a half life of 13 hours. So its action in body from a dose lasts that long. Also cortisol quickly interrupts progesterone's actions.

Hopes this helps.