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MelaNon - Liquid Apigenin/Naringenin Mix

Discussion in 'IdeaLabs' started by haidut, Nov 10, 2015.

  1. Albina

    Albina Member

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    Would this work on a vascular lake located on the lower lip?
     
  2. OP
    haidut

    haidut Member

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    It may as apigenin is considered a phytoprogestin, and progesterone seems to help such issues.
     
  3. Albina

    Albina Member

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    thanks - it's worth a try! Derm said nothing could be done to remove it.
     
  4. Lee Simeon

    Lee Simeon Member

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    @haidut Do you think this could have any beneficial systemic effects? And what is the reason for removing caffeine on this product?
     
  5. OP
    haidut

    haidut Member

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    Not sure if it would have systemic effects from such small doses but apigenin and naringenin are 11b-HSD1 inhibitors, so could lower cortisol in some people.
    Comparison of flavonoids and isoflavonoids to inhibit rat and human 11β-hydroxysteroid dehydrogenase 1 and 2. - PubMed - NCBI

    Caffeine was affecting the solubility of apigenin and naringenin so we decided to remove it, especially considering that it was not the main active ingredient anyways.
     
  6. Albina

    Albina Member

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    @haidut. I accidentally put a drop of melanon in my eye (thought it was my morning eye drop). Attempted to wash it out and it still is burning. Will this harm my eye?
     
  7. OP
    haidut

    haidut Member

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    One drop is probably not going to do much/any damage. The only risky part is the ethanol but there is not much ethanol in one drop. If the redness/irritation does not subside within a few days I would see a doctor but as I mentioned there is nothing really dangerous in MelaNon and the ethanol in one drop is unlikely to cause issues. That being said, I would not apply MelaNon to the eye :):
     
  8. Albina

    Albina Member

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    Thanks so much for your quick response. Of course I’m late now for a root canal that has failed 3 times so I don’t have time to continue washing the eye. When I get back I will irrigate again - it’s pretty red and sore.
     
  9. Kaka

    Kaka New Member

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    I've stumbled across this, and I'd like to ask: has anyone had success with it for broken capillaries? The DMSO sounds interesting, as I believe it takes ingredients through the skin barrier, presumably to where they need to be to heal these things?
     
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