Magnesium Sulfate Can Improve Arrhythmias But Not As Good As Lidocaine

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Antiarrhythmic effect of magnesium sulfate after open heart surgery: effect of blood levels. - PubMed - NCBI


Int J Cardiol. 2003 Jun;89(2-3):153-8.
Antiarrhythmic effect of magnesium sulfate after open heart surgery: effect of blood levels.
Kiziltepe U1, Eyileten ZB, Sirlak M, Tasoz R, Aral A, Eren NT, Uysalel A, Akalin H.

" Magnesium sulfate is an effective antiarrhythmic agent with negligible side effects. In this study, effects of magnesium sulfate as a first line antiarrhythmic agent was compared with results of two different well-accepted antiarrhythmic agents."

"Lidocaine and amiodarone were accepted as standard antiarrhythmic agents."

"Magnesium sulfate alone was effective in 56% of the study group whereas 74% of the control group were responsive to standard antiarrhythmics (P=n.s.). 2"

"Magnesium sulfate is an effective and safe antiarrhythmic agent for arrhythmias developed after open-heart surgery. Its antiarrhythmic effect may relate to its pharmacological properties and unrelated to normalization of the circulating magnesium concentrations. We recommend its use as a first line antiarrhythmic agent without routine measurement of blood levels"
 
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