Amazoniac
Member
Beliebers,
This review was written in a weird manner because I guess the guy had more freedom than what we would expect from a researcher in a published review. Nevertheless, I’m sharing because it has some interesting points that can direct people here to look for those subjects in more depth.
The multifaceted and widespread pathology of magnesium deficiency. - PubMed - NCBI
“Delirium tremens is caused partly by very low serum levels of glucose, Mg, P and B vitamins. Mg greatly affects muscle by inhibiting the release of acetylcholine, the neurotransmitter that triggers muscle contraction (4). Accordingly, in delirium tremens, the low levels of Mg increase the release of acetylcholine, producing massive involuntary contractions.”
“Furthermore, prolonged, intense stress, especially in the absence of Mg-rich foods and sun light, increases considerably Mg elimination (and therefore, Ca and K elimination).”
“..Moreover, a Se deficiency also increases Mg elimination and causes Fe accumulation (5).”
“Mg is necessary for activation of most of the ATPases, so that low Mg levels result in impaired transport of K, H, Na, Ca, etc. Because the kidneys require Mg in order to recycle Ca, P and K and to eliminate excess Na, Cl, Pb and Cd. A Mg deficiency eventually leads to low levels of Ca and K and to high levels of Na, Cl, Cd and Pb. This electrolytic imbalance leads to hypertension and to intracellular disturbances at the mitochondrial level. In turn, the hypertension eventually leads to cardiovascular damage, renal and hepatic damage, increased risk of aneurysms and internal hemorrhages, and many other diseases.”
“Thiamine (vitamin B1) forms thiamine pyrophosphate in the presence of Mg. When the latter is not available, thiamine cannot perform properly (10) (see Fig. 4). The result is an apparent thiamine deficiency, even when the body has enough or excess thiamine. The lack of performance of thiamine results in low levels of gastric acid (low levels of secretin, leading to autism), leading to increased risk of GI infections and to impaired digestion and in damage to the hypothalamus (confusion, delusions, hallucinations, disorientation, Wernicke’s encephalopathy (11), Alzheimer’s disease, etc.). The lack of Mg also leads to the formation of calcium pyrophosphate, instead of thiamine pyrophosphate. Calcium pyrophosphate can precipitate in painful crystals (pseudogout).”
“Magnesium also plays a crucial role in the release of nitric oxide (NO) from the cell. NO serves many functions (see Figs 2, 3 and 6), among the most important is preventing infections in the body cavities, such as the sinuses, throat, lungs, vagina, larynx, etc.”
“NO deficiency may also play a role in arteriosclerosis induced by low Mg levels, since Chlamydia p, is suspected of contributing this disease, and low NO levels may favor this bacterium.”
“..Furthermore, the accumulation of NO in the cell causes formation of peroxynitrite, an extremely reactive substance formed by the reaction of NO with superoxide, which causes massive oxidative damage to the cell.”
“The combination of hypertension, impaired perfusion, and cellular damage leads to migraines (13), multiple sclerosis, impotence (NO causes the vasodilation responsible for an erection), glaucoma, strokes, etc. (see Fig. 6).”
“As we mentioned above, Mg inhibits the release of acetylcholine, so that low Mg levels lead to uncontrollable muscle contractions (see Fig. 6). This can be seen in delirium tremens, myasthenia gravis, Guillain-Barre syndrome, etc.”
“A Mg deficiency affects greatly the distribution of several minerals in the body, for example, it increases Fe levels in liver, spleen and kidney at the same time that it reduces Cu levels in the liver (14). The accumulation of Fe, Cd, Al and Pb in the kidneys, liver and brain, that results from, and exacerbates, a Mg deficiency, leads to considerable oxidative damage of these crucial organs. The brain damage eventually manifests itself as many devastating diseases such as autism (15–17), Parkinson’s disease, etc.”
As always, I’m merely sharing, questions should be adressed to burtlancast.
This review was written in a weird manner because I guess the guy had more freedom than what we would expect from a researcher in a published review. Nevertheless, I’m sharing because it has some interesting points that can direct people here to look for those subjects in more depth.
The multifaceted and widespread pathology of magnesium deficiency. - PubMed - NCBI
“Delirium tremens is caused partly by very low serum levels of glucose, Mg, P and B vitamins. Mg greatly affects muscle by inhibiting the release of acetylcholine, the neurotransmitter that triggers muscle contraction (4). Accordingly, in delirium tremens, the low levels of Mg increase the release of acetylcholine, producing massive involuntary contractions.”
“Furthermore, prolonged, intense stress, especially in the absence of Mg-rich foods and sun light, increases considerably Mg elimination (and therefore, Ca and K elimination).”
“..Moreover, a Se deficiency also increases Mg elimination and causes Fe accumulation (5).”
“Mg is necessary for activation of most of the ATPases, so that low Mg levels result in impaired transport of K, H, Na, Ca, etc. Because the kidneys require Mg in order to recycle Ca, P and K and to eliminate excess Na, Cl, Pb and Cd. A Mg deficiency eventually leads to low levels of Ca and K and to high levels of Na, Cl, Cd and Pb. This electrolytic imbalance leads to hypertension and to intracellular disturbances at the mitochondrial level. In turn, the hypertension eventually leads to cardiovascular damage, renal and hepatic damage, increased risk of aneurysms and internal hemorrhages, and many other diseases.”
“Thiamine (vitamin B1) forms thiamine pyrophosphate in the presence of Mg. When the latter is not available, thiamine cannot perform properly (10) (see Fig. 4). The result is an apparent thiamine deficiency, even when the body has enough or excess thiamine. The lack of performance of thiamine results in low levels of gastric acid (low levels of secretin, leading to autism), leading to increased risk of GI infections and to impaired digestion and in damage to the hypothalamus (confusion, delusions, hallucinations, disorientation, Wernicke’s encephalopathy (11), Alzheimer’s disease, etc.). The lack of Mg also leads to the formation of calcium pyrophosphate, instead of thiamine pyrophosphate. Calcium pyrophosphate can precipitate in painful crystals (pseudogout).”
“Magnesium also plays a crucial role in the release of nitric oxide (NO) from the cell. NO serves many functions (see Figs 2, 3 and 6), among the most important is preventing infections in the body cavities, such as the sinuses, throat, lungs, vagina, larynx, etc.”
“NO deficiency may also play a role in arteriosclerosis induced by low Mg levels, since Chlamydia p, is suspected of contributing this disease, and low NO levels may favor this bacterium.”
“..Furthermore, the accumulation of NO in the cell causes formation of peroxynitrite, an extremely reactive substance formed by the reaction of NO with superoxide, which causes massive oxidative damage to the cell.”
“The combination of hypertension, impaired perfusion, and cellular damage leads to migraines (13), multiple sclerosis, impotence (NO causes the vasodilation responsible for an erection), glaucoma, strokes, etc. (see Fig. 6).”
“As we mentioned above, Mg inhibits the release of acetylcholine, so that low Mg levels lead to uncontrollable muscle contractions (see Fig. 6). This can be seen in delirium tremens, myasthenia gravis, Guillain-Barre syndrome, etc.”
“A Mg deficiency affects greatly the distribution of several minerals in the body, for example, it increases Fe levels in liver, spleen and kidney at the same time that it reduces Cu levels in the liver (14). The accumulation of Fe, Cd, Al and Pb in the kidneys, liver and brain, that results from, and exacerbates, a Mg deficiency, leads to considerable oxidative damage of these crucial organs. The brain damage eventually manifests itself as many devastating diseases such as autism (15–17), Parkinson’s disease, etc.”
As always, I’m merely sharing, questions should be adressed to burtlancast.