Low dose DHEA restores insulin sensitivity by increasing DHT

haidut

Member
Forum Supporter
Joined
Mar 18, 2013
Messages
19,799
Location
USA / Europe
This is one study that used doses of DHEA close to what Peat would recommend, and not the megadosing schedules likely to result in conversion into estrogen. The human equivalent dose was <15mg per day and resulted in 71% increases in DHT. It is that increase in DHT and DHEA levels that is behind the beneficial effects of exercise (e.g. restored insulin sensitivity) and the supplementation regimen for 6 weeks resulted in essentially the same benefits as exercise.
Given that DHEA also opposes cortisol, which is well known to cause the belly fat accumulation, maybe it is worth trying a low dose DHEA if you have a problem with weight gain, insulin and belly fat.
Btw, the study did not measure if DHEA also increased estrogen but given that it increased DHT and the dose was low I think it is unlkely that estrogen went up as a result of DHEA supplementation.

DHEA administration and exercise training improves insulin resistance in obese rats
 
Last edited:

mgrabs

Member
Joined
Nov 29, 2022
Messages
519
Location
USA
This is one study that used doses of DHEA close to what Peat would recommend, and not the megadosing schedules likely to result in conversion into estrogen. The human equivalent dose was <15mg per day and resulted in 71% increases in DHT. It is that increase in DHT and DHEA levels that is behind the beneficial effects of exercise (e.g. restored insulin sensitivity) and the supplementation regimen for 6 weeks resulted in essentially the same benefits as exercise.
Given that DHEA also opposes cortisol, which is well known to cause the belly fat accumulation, maybe it is worth trying a low dose DHEA if you have a problem with weight gain, insulin and belly fat.
Btw, the study did not measure if DHEA also increased estrogen but given that it increased DHT and the dose was low I think it is unlkely that estrogen went up as a result of DHEA supplementation.

DHEA administration and exercise training improves insulin resistance in obese rats
Does dhea increase dht no matter what dose?
 
EMF Mitigation - Flush Niacin - Big 5 Minerals

Similar threads

Back
Top Bottom