HDD

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Nov 1, 2012
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Would be awesome to have a testimony of someone right there with MS who have good results with this thread or any other on this forum about MS.
Please let us know lol

I used aspirin among other supplements and dietary changes the last time I had serious MS symptoms.

I currently have no MS symptoms and haven’t in 7 years.
 

Texon

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Nov 28, 2016
Messages
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I used aspirin among other supplements and dietary changes the last time I had serious MS symptoms.

I currently have no MS symptoms and haven’t in 7 years.
What were other supplements and dietary changes if you don't mind discussing?
 

HDD

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Nov 1, 2012
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What were other supplements and dietary changes if you don't mind discussing?
I’ve posted about it before, but I can’t easily locate it now. I had found Ray Peat by googling “ms and fats”. He had an article on MS with things he thought could be helpful. I started using all the supplements he suggested that I could find at my local health food store. I quit my Paleo diet and worked on improving my metabolism via diet and supplements. I used high doses of aspirin initially because I felt my symptoms were serious and also because I didn’t have a clue what I was doing.

“Nutritional supplements that might help to prevent or correct these brain syndromes include: Vitamin E and coconut oil; vitamin A; magnesium, sodium; thyroid which includes T3; large amounts of animal protein, especially eggs; sulfur, such as magnesium sulfate or flowers of sulfur, but not to take continuously, because of sulfur's interference with copper absorption; pregnenolone; progesterone if needed. Bright light, weak in the blue end of the spectrum and with protection against ultraviolet, activates respiratory metabolism and quenches free radicals. Raw carrot fiber and/or laxatives if needed; charcoal occasionally for gas or bowel irritation. Coconut oil serves several purposes. Its butyric acid is known to increase T3 uptake by glial cells.”
MULTIPLE SCLEROSIS AND OTHER HORMONE-RELATED BRAIN SYNDROMES.
 

Bogdar

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Messages
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I used aspirin among other supplements and dietary changes the last time I had serious MS symptoms.

I currently have no MS symptoms and haven’t in 7 years.
Amazing. Are/were you followed by a specialist ? From your post I can't decide if you had a proper diagnostic or not.
 

HDD

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Amazing. Are/were you followed by a specialist ? From your post I can't decide if you had a proper diagnostic or not.
Due to symptoms, I initially sought medical help. I was referred to a neurologist. The diagnosis was given by a “specialist”, a neurologist, following the “proper diagnostics”, an MRI and a spinal tap. There was no treatment plan at that time (1988). I was given “The MS Diet Book” by a family member, that I followed loosely for a few years.

I haven’t been to a neurologist in over 20 years. At my last appointment, he recommended that I take the latest treatment, interferon injections, since I was “declining”. I declined his treatment and have not returned to a doctor for any MS symptoms.
 

Bogdar

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Sep 5, 2018
Messages
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Due to symptoms, I initially sought medical help. I was referred to a neurologist. The diagnosis was given by a “specialist”, a neurologist, following the “proper diagnostics”, an MRI and a spinal tap. There was no treatment plan at that time (1988). I was given “The MS Diet Book” by a family member, that I followed loosely for a few years.

I haven’t been to a neurologist in over 20 years. At my last appointment, he recommended that I take the latest treatment, interferon injections, since I was “declining”. I declined his treatment and have not returned to a doctor for any MS symptoms.
Thank you for the details ! You have an interesting story here.
 

Texon

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Nov 28, 2016
Messages
668
Due to symptoms, I initially sought medical help. I was referred to a neurologist. The diagnosis was given by a “specialist”, a neurologist, following the “proper diagnostics”, an MRI and a spinal tap. There was no treatment plan at that time (1988). I was given “The MS Diet Book” by a family member, that I followed loosely for a few years.

I haven’t been to a neurologist in over 20 years. At my last appointment, he recommended that I take the latest treatment, interferon injections, since I was “declining”. I declined his treatment and have not returned to a doctor for any MS symptoms.
Were you declining somehow, or was that just his way of planting a "thought bomb"? Also, did you ever try LDN/Low Dose Naltrexone in the meantime?
 

Texon

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Joined
Nov 28, 2016
Messages
668
Due to symptoms, I initially sought medical help. I was referred to a neurologist. The diagnosis was given by a “specialist”, a neurologist, following the “proper diagnostics”, an MRI and a spinal tap. There was no treatment plan at that time (1988). I was given “The MS Diet Book” by a family member, that I followed loosely for a few years.

I haven’t been to a neurologist in over 20 years. At my last appointment, he recommended that I take the latest treatment, interferon injections, since I was “declining”. I declined his treatment and have not returned to a doctor for any MS symptoms.
Also, I just found this from www.orthomolecular.org
The doses are very high compared to low dose aspirin. Wonder if the 2 could be combined safely at much lower doses for the niacin?

"However, there is excellent evidence that adequate doses of essential nutrients can effectively treat MS -- and they're inexpensive. Sound to good to be true? Niacin (also called nicotinic acid) can activate the same receptor as dimethyl fumarate (DMF; TecfideraTM) and this can be done for $15 a month instead of $5,000! [8] Niacin has a long history of use in the treatment of a variety of neurological and autoimmune diseases, but it is commonly ignored in treatments offered at the clinic [9,10]. Niacin costs just cents per gram and 3 grams per day is a typical high dose niacin regimen that has been and continues to be used for over 60 years [11]. After treating thousands of patients throughout his life with high-dose niacin therapy Dr. Abram Hoffer, MD, PhD, (1917-2009) settled on this dosage: 3-18g/d in divided (3x daily) doses for neurological disease [9]. Further comparative analysis of dimethyl fumarate vs. niacin as related to safety and effectiveness is presented in sections below. Let's consider the safety profile of dimethyl fumarate (DMF) compared to high dose niacin therapy. DMF was banned 2009 in Europe for certain applications due to skin reactions and has been only used for MS since 2013 [12]. Meanwhile, high dose niacin therapy has been safely used for over 60 years [11, 13]."
 

Vinny

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I haven’t been to a neurologist in over 20 years. At my last appointment, he recommended that I take the latest treatment, interferon injections, since I was “declining”. I declined his treatment and have not returned to a doctor for any MS symptoms.
That`s mind-blowing, man! You`re a beast!
 

HDD

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Nov 1, 2012
Messages
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Were you declining somehow, or was that just his way of planting a "thought bomb"? Also, did you ever try LDN/Low Dose Naltrexone in the meantime?
I was having a bad flare up at the time. I hadn’t had one in over 10 years and had not been back to the neurologist. I did not agree with his declining statement because I had been symptom free for so many years. Since my symptoms were as extreme as when I was diagnosed, I suspected I might be pregnant (I was pregnant when I had my first major flare up). The first thing I did was get a pregnancy test and I was, in fact, pregnant. I now believe that my symptoms are due to estrogen/low thyroid/low vitamin D. I have felt what I previously would have called an MS symptom (weakness, numbness, pain) when my temperature is very low.

No, I haven’t tried LDN. I mainly try to focus on diet and thyroid function.
 

Peatogenic

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Sep 11, 2017
Messages
746
A few years ago I posted a study showing that 1.2g aspirin daily greatly ameliorated fatigue in MS patients and was considered safe enough even at that high dose to be recommended for daily use.
Sunlight And Aspirin Can Treat Multiple Sclerosis (MS)

However, those studies did not look at whether aspirin actually affected the clinical course of the disease, even though the reduction of fatigue strongly suggested that it did. This new study below shows that aspirin not only blocks the relapses of MS but halts the progression of the disease and completely restores the lost myelin in the nerves, after only 8 days of treatment. These dramatic results were seen in doses even below a "baby aspirin" (81 mg) daily. The HED of aspirin doses used in the study were 0.07 mg/kg and 0.15 mg/kg. The proposed mechanism of action for aspirin was the reduction of inflammatory burden, including nitric oxide (NO). So much for the "benefits" of NO. I am beginning to wonder if the recent spike in MS diagnoses in men is not at least partially due to the boom in sales of Viagra-type drugs.
In light of the shockingly successful trial with high-dose biotin, I am afraid it won't be long before both biotin and aspirin get labelled as prescription drugs only. Unlike pregnenolone and DHEA, I don't think there is a law protecting these chemicals from encroachment by the FDA and Big Pharma. So, as was shown in the case of pyridoxamine, if a company performs a clinical trials with aspirin for MS and shows it is effective then that company can petition the FDA to withdraw aspirin from the market. The company running the trials with biotin already petitioned FDA to ban all OTC products that contain more than 1mg biotin per pill/dose. No decision on that yet, but the process has already been put in motion and aspirin could be next.

Aspirin ameliorates experimental autoimmune encephalomyelitis through interleukin-11–mediated protection of regulatory T cells
"...We observed marked expression of proinflammatory molecules like iNOS and IL-1 in spinal cord tissue from untreated RR-EAE mice when compared to control mice (fig. S1A and Fig. 2, D and E). However, aspirin treatment markedly suppressed the mRNA expression of iNOS and IL-1 in spinal cord tissue from mice with RR-EAE (fig. S1A and Fig. 2, D and E)."

"...Additionally, recombinant human IL-11 markedly suppresses bacterial lipopolysaccharide-induced NO production from macrophages (35). Therefore, it is possible that IL-11 prevented conversion of Tregs in EAE mice by suppressing the production of NO."

"...Here, we describe a new function of aspirin in which this drug inhibits the autoimmune disease EAE. Oral use of low-dose aspirin reduced the progression of both adoptively transferred and chronic EAE in mice. Aspirin treatment of mice with EAE also inhibited the invasion of mononuclear cells into the spinal cord as well as the expression of inflammatory molecules [inducible nitric oxide synthase (iNOS) and IL-1] and restored myelination and the expression of myelin-specific genes within the CNS. A recent double-blind randomized controlled pilot trial suggests that aspirin may represent an effective pretreatment for exercise in MS (29). Fatigue is very common in MS, and low-dose aspirin is also being considered for treating MS-related fatigues (30). Here, our preclinical data suggest that low-dose aspirin may be repurposed for disease modification in MS patients.

"...Although at high doses aspirin is reported to exhibit some toxic effects (gastric ulcers, stomach bleeding, tinnitus, etc.) (38), in our study aspirin suppressed the disease process of EAE at low doses (1 and 2 mg/kg body weight per day). A single pill of baby aspirin containing 81 mg of aspirin is considered to be very much safe for adults for daily use, and the doses we used in mice are almost equivalent to baby aspirin."

Lose-dose aspirin may help fight MS, study with mice says
"...Although the findings are so far only in mice, studies suggest that aspirin -- even the "low-dose" variety -- might help counter multiple sclerosis. Multiple sclerosis, or MS, is an autoimmune disorder where aberrant immune system T-cells attack and destroy the protective myelin protein sheath that coats nerves."

"...For the study, Mondal's team fed aspirin to mice specially bred to mimic the human form of MS. The investigators found that even low doses of aspirin -- equal to the 81 milligram "baby aspirin" many take to ward off heart trouble -- seemed to curb symptoms of MS in the mice. What's more, the pain reliever seemed to push back the underlying disease itself. "

"..."Although mouse results are not always translated to humans, our results highlight an undiscovered property of aspirin and suggest that low-dose aspirin may be repurposed for therapeutic intervention in MS," the study team wrote."

Do you think Aspirin has a good shelf life? You know, in case you wanted to be an aspirin prepper.
 

lampofred

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Feb 13, 2016
Messages
3,244
I used aspirin among other supplements and dietary changes the last time I had serious MS symptoms.

I currently have no MS symptoms and haven’t in 7 years.

Wow. That is amazing. Congratulations!
 

kitback

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Joined
Dec 5, 2012
Messages
46
I don’t have an official diagnosis but I believe I have been dealing with MS for more than two years. I believe it was brought on by mold exposure over a period of several months which really trashed my immune system.

Over the course of the past two years, I have been dealing with nerve pain in my torso, leg muscle weakness, especially when exposed to heat and humidity, lesions in various places of my body that would not heal, very low body temperature, weight gain, extreme fatigue and very little stamina, and worst of all, vision loss. I had to give up driving last year. The vision loss has been progressive. It was my first symptom starting with blurry vision two years ago which progressed to double vision, grayed out vision, to the point where I could only see about 8 inches in front of my face.

I have been Peating since 2010. I am a 66-year-old obese female. For most of these years, I have been taking T3, T3/T4, 400 mg of aspirin, Niacinamide, Thiamine , pregnenolone , progesterone, K2, biotin, and Riboflavin (B2). I also started taking vitamin A and vitamin D about a year ago. I discovered I was suffering from a severe vitamin D deficiency, my level was 15. Now it is 32.

Haidut posted a study some time ago about the synergistic effect of taking Taurine with T3 in remyelinating nerves. As soon as I did that, it put an immediate end to the burning nerve pain in various areas of my torso, it also improved my stamina and strength. Just the reduction of pain was a great gift. There was no improvement with my vision, however.

Then I read a recent post by Haidut about adding glucose to the diet to improve MS symptoms. I started that about two weeks ago. This also increased my stamina and strength and helped increase my body temperature, allowing me to reach 98.6° on occasion which had not been possible for some time. However, my body temperature continued to fluctuate wildly, dropping from 98.3°F to 97.0° within a few hours. My temperature was like a roller coaster ride. The lesions on my body begin to heal. There were some slight improvements with my vision, where I was able to see 10 inches in front of my face instead of eight, then 12. Beyond that everything was a big gray blur.

After reading a couple of studies posted by Haidut on the effect of aspirin on MS, I decided to double my daily dose a few days ago. Instead of taking 400 mg once a day, I started taking 400 mg twice a day. I check my body temperature frequently now and after just a couple of days of the aspirin, my body was regulating my temperature much better! It stayed within the range of 97.6°F to 98.6°F. I could live with that, much better than the roller coaster ride my body temperature had been on. And the other very exciting change I am noticing is more significant improvement in my vision! For the last six months or more, wearing my eyeglasses made almost no difference in my vision. A gray blurry blob looked pretty much the same with glasses on or off. And I have very poor distance vision without glasses so I have a strong prescription. Sometimes I wouldn’t even bother to put them on. But in the past couple of days, the glasses are making a significant difference in my vision which tells me that something good is happening and things might be reversing! And I can now see close to 2 feet in front of my face which is way better than the 8 inches I started off with! I would LOVE to get my vision back so I can drive again and be more independent. With so much improvement in such a short time, I am optimistic! And other than the vision issues, due to all the other improvements, I wouldn’t really even know I have MS at this point.
 

A.R

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Joined
Oct 14, 2016
Messages
893
I don’t have an official diagnosis but I believe I have been dealing with MS for more than two years. I believe it was brought on by mold exposure over a period of several months which really trashed my immune system.

Over the course of the past two years, I have been dealing with nerve pain in my torso, leg muscle weakness, especially when exposed to heat and humidity, lesions in various places of my body that would not heal, very low body temperature, weight gain, extreme fatigue and very little stamina, and worst of all, vision loss. I had to give up driving last year. The vision loss has been progressive. It was my first symptom starting with blurry vision two years ago which progressed to double vision, grayed out vision, to the point where I could only see about 8 inches in front of my face.

I have been Peating since 2010. I am a 66-year-old obese female. For most of these years, I have been taking T3, T3/T4, 400 mg of aspirin, Niacinamide, Thiamine , pregnenolone , progesterone, K2, biotin, and Riboflavin (B2). I also started taking vitamin A and vitamin D about a year ago. I discovered I was suffering from a severe vitamin D deficiency, my level was 15. Now it is 32.

Haidut posted a study some time ago about the synergistic effect of taking Taurine with T3 in remyelinating nerves. As soon as I did that, it put an immediate end to the burning nerve pain in various areas of my torso, it also improved my stamina and strength. Just the reduction of pain was a great gift. There was no improvement with my vision, however.

Then I read a recent post by Haidut about adding glucose to the diet to improve MS symptoms. I started that about two weeks ago. This also increased my stamina and strength and helped increase my body temperature, allowing me to reach 98.6° on occasion which had not been possible for some time. However, my body temperature continued to fluctuate wildly, dropping from 98.3°F to 97.0° within a few hours. My temperature was like a roller coaster ride. The lesions on my body begin to heal. There were some slight improvements with my vision, where I was able to see 10 inches in front of my face instead of eight, then 12. Beyond that everything was a big gray blur.

After reading a couple of studies posted by Haidut on the effect of aspirin on MS, I decided to double my daily dose a few days ago. Instead of taking 400 mg once a day, I started taking 400 mg twice a day. I check my body temperature frequently now and after just a couple of days of the aspirin, my body was regulating my temperature much better! It stayed within the range of 97.6°F to 98.6°F. I could live with that, much better than the roller coaster ride my body temperature had been on. And the other very exciting change I am noticing is more significant improvement in my vision! For the last six months or more, wearing my eyeglasses made almost no difference in my vision. A gray blurry blob looked pretty much the same with glasses on or off. And I have very poor distance vision without glasses so I have a strong prescription. Sometimes I wouldn’t even bother to put them on. But in the past couple of days, the glasses are making a significant difference in my vision which tells me that something good is happening and things might be reversing! And I can now see close to 2 feet in front of my face which is way better than the 8 inches I started off with! I would LOVE to get my vision back so I can drive again and be more independent. With so much improvement in such a short time, I am optimistic! And other than the vision issues, due to all the other improvements, I wouldn’t really even know I have MS at this point.
This was a great read, hope things keep improving for you! Seems as though Taurine, T3 and Glucose were the real game changers for you.

Could you do a approximate write up of your diet please?
 

kitback

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Joined
Dec 5, 2012
Messages
46
This was a great read, hope things keep improving for you! Seems as though Taurine, T3 and Glucose were the real game changers for you.

Could you do a approximate write up of your diet please?

Aspirin has also been a huge game changer, maybe the biggest in that it has regulated my wildly fluctuating body temperature, increased my metabolism, and caused significant improvements in my vision. For me, the dose was an important factor since I was already taking 400 mg daily without much effect. It was only after I added a second 400 mg dose that all these improvements happened. Taurine and glucose also provided significant benefits as stated above.

I call my diet “Peat inspired intuitive eating”. I have been eating this way for 6 years. I do restrict PUFAs, using primarily butter, coconut oil, and a small amount of olive oil in my diet. My primary protein sources are eggs, cheese, milk, and ice cream, with usually one serving of meat or shellfish once a day. I consume fruit juice, Mexican Coke, and coffee with lots of sugar and half-and-half daily. Usually have one or two servings of fruit each day. I do eat starch but not with every meal – usually pasta which works best for my blood sugar, sometimes potatoes with lots of fat. Often a small serving of chocolate after dinner. Veggies as desired.
 
OP
haidut

haidut

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Do you think Aspirin has a good shelf life? You know, in case you wanted to be an aspirin prepper.

It tends to break down into salicylic and acetic acid over time, even when stored in the fridge. However, salicylic acid (which is the "active ingredient") is pretty stable and can last for many years when kept in the fridge. So, even though aspirin may start to break down it will still retain its effectiveness. I guess you can always buy in bulk something like sodium salicylate, which is quite stable and can last indefinitely when kept at low temps and in a well-closed container.
 

cedric

Member
Joined
Jul 26, 2018
Messages
156
You can just chew willow leaves(bitter) and twigs. It is life extending.
The many uses of the willow
Willow Weep For Me - Eat The Weeds and other things, too

Polyunsaturated fatty acids in the pathogenesis and treatment of multiple sclerosis. - PubMed - NCBI

Br J Nutr. 2007 Oct;98 Suppl 1:S46-53.
Polyunsaturated fatty acids in the pathogenesis and treatment of multiple sclerosis.
Harbige LS1, Sharief MK.

Distorted metabolism Omega6 and GLA supplementation

Cerebral hypoperfusion in multiple sclerosis is
reversible and mediated by endothelin-1

https://www.pnas.org/content/pnas/110/14/5654.full.pdf

Brain iron levels may predict multiple sclerosis disabilities
Date:
July 17, 2018
Brain iron levels may predict multiple sclerosis disabilities

Inosine increases uric acid-strong peroxynitrate scavenger
https://www.pnas.org/content/pnas/95/2/675.full.pdf

Proc. Natl. Acad. Sci. USA
Vol. 95, pp. 675–680, January 1998
Medical Sciences
Uric acid, a natural scavenger of peroxynitrite, in experimental
allergic encephalomyelitis and multiple sclerosis
D. C. HOOPER*†, S. SPITSIN†, R. B. KEAN*, J. M. CHAMPION*, G. M. DICKSON*, I. CHAUDHRY*,
AND H. KOPROWSKI*‡

Methanol linked to SM?
http://www.whilesciencesleeps.com/multiple-sclerosis-the-solution/
Low B1/ B12

Strange history of Aspartame
Donald Rumsfeld and the Strange History of Aspartame | HuffPost

Excessive CO and CN
Multiple Sclerosis & Other Hormone-Related Brain Syndromes – Functional Performance Systems (FPS)

Low cytochrome c oxidase in SM?
Herb Common Acne Medication Offers New Treatment for Multiple Sclerosis

Common acne medication offers new treatment for multiple sclerosis: Study results offer safe and affordable treatment option
fumarate, B2, B3
silica and boron-aluminium , heavy metal chelators

Histamine -J.Wright
https://www.tldp.com/issue/11_00/ms.htm

IBT drainage instead of CCSVI?
http://inclinedbedtherapy.com/

https://it.wikipedia.org/wiki/Matteo_Dall'Osso
http://www.matteodallosso.org/eng/
 

GreekDemiGod

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Joined
Aug 9, 2019
Messages
3,325
Location
Romania
I was wondering if more advanced forms of MS are curable. I got informed that a friend of a friend has it, they are opting for a stem cell (HSCT) treatment in a Russian clinic.
She mentioned: "He (the guy who has MS) has a more advanced form of MS. A few 'spots' on the brain and spine + numbness in hands and legs + horrible headaches + terrible fatigue.

@haidut
 

Jon2547

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Joined
Mar 2, 2021
Messages
719
Here is how they will be able to make aspirin either completely banned or by prescription only: The newsmedia will highlight a couple of cases where kids gets ahold of some aspirin and takes too much ( in other words, they will create a sense of danger) and then they have some unwitting Karens (and Lindas and Nancys) raise a stink and demand that aspirin be regulated. And none of us will be able to do anything about it.

After the year 2020 happened, we see that anything is possible with the Controllers.
 

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