Like night and day: Animal studies may not translate to humans if time of day is disregarded

[charlie]

“There are these dramatic daily fluctuations—in metabolism, in immune function, in learning and memory, in perception—and by the large, they get ignored,” said Randy Nelson, who led the study. “You just have to wonder: to what extent is that affecting the outcomes?”

"Even among the studies conducted at night, most didn’t describe in detail how the authors protected the rodents’ circadian rhythms. For example, at what times did the researchers observe the animals? Did they house the animals in the dark during the day? If so, how did they keep extraneous light from invading the room every time someone opened the door or turned on a hallway light? In most cases, it’s impossible to tell from the methods section."

"Failing to account for time of day doesn’t just jeopardize an animal study’s reproducibility. It can also make its results less applicable to humans."

WVU Today | Like night and day: Animal studies may not translate to humans if time of day is disregarded

Imagine being woken up at 3 a.m. to navigate a corn maze, memorize 20 items on a shopping list or pass your driver’s test. According to a new analysis out of West Virginia University, that’s often what it’s like to be a rodent in a biomedical study. Mice and rats, which make up the vast...

wvutoday.wvu.edu

 

[Tarmander]

I also think about where they do these tests. IE universities that have strong cell phone tower presence.

So many studies from this age are going to be just junk to be thrown out

What was it Nietzsche said, something like the real test now is whether truth can be institutionalized.

 

[charlie]

I also think about where they do these tests. IE universities that have strong cell phone tower presence.

So many studies from this age are going to be just junk to be thrown out

What was it Nietzsche said, something like the real test now is whether truth can be institutionalized.

I agree, any studies done within the manmade grid have to be questioned. How can you get true results within a fake magnetic, electrical, and radio field?

 

[Rinse & rePeat]

“There are these dramatic daily fluctuations—in metabolism, in immune function, in learning and memory, in perception—and by the large, they get ignored,” said Randy Nelson, who led the study. “You just have to wonder: to what extent is that affecting the outcomes?”

"Even among the studies conducted at night, most didn’t describe in detail how the authors protected the rodents’ circadian rhythms. For example, at what times did the researchers observe the animals? Did they house the animals in the dark during the day? If so, how did they keep extraneous light from invading the room every time someone opened the door or turned on a hallway light? In most cases, it’s impossible to tell from the methods section."

"Failing to account for time of day doesn’t just jeopardize an animal study’s reproducibility. It can also make its results less applicable to humans."

WVU Today | Like night and day: Animal studies may not translate to humans if time of day is disregarded

Imagine being woken up at 3 a.m. to navigate a corn maze, memorize 20 items on a shopping list or pass your driver’s test. According to a new analysis out of West Virginia University, that’s often what it’s like to be a rodent in a biomedical study. Mice and rats, which make up the vast...

wvutoday.wvu.edu

Yeah this is like developing film in a dark room and thinking the light doesn’t matter. This is why I wonder how accurate blood tests can be with so many variables that are continually changing according to food, sleep, stress and light.

 

[Rinse & rePeat]

“Interestingly enough, the study sounds an alarm about the fluorescent lights used in most animal care facilities, warning that long exposure to such light may be affecting the outcome of animal studies and needs to be a factor controlled for in statistical analysis. Yet, the study is silent about the same light exposure of humans in office buildings or at home. I guess, research animals are more valuable to the medical industry than a few billion peons wasting away in office buildings designed after maximum security prisons...”

Blue Light Accelerates Aging And Reduces Lifespan By More Than 50%

In one of his interviews, Peat mentioned that red light exposure may be the most fundamental protective factor in nature, and that a deficiency of it (as commonly seen in Western lifestyles) may be the main driver of systemic aging and the diseases associated with it. The study below provides...

raypeatforum.com

 

[Blossom]

Great thread. It explains a lot.