Lidocaine Protects Liver From Calcium Overload

Adrenaline

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Although mainstream information says that Lidocaine may have hepatotoxic effects, studies show that it may have liver protective effects. I recently shared a study here that shows Lidocaine protects liver and kidneys from endotoxin/TLR4.

Here another study shows that Lidocaine protects liver from calcium overload and hypoxia.

[Effect of lidocaine precondition on hepatocytes calcium overload and apoptosis induced by cell hypoxia-reoxygenation]. - PubMed - NCBI

CONCLUSION: Precondition with lidocaine can attenuate calcium overload of hepatocytes induced by hypoxia-reoxygenation in vitro,and decrease the ratio of apoptosis.

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