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L-Carnitine Is Anti-thyroid

Discussion in 'Scientific Studies' started by haidut, Apr 16, 2014.

  1. Joeyd

    Joeyd Member

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  2. rei

    rei Member

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    It is, like most things, not good or bad. But situation dependent. If you are trying to lose weight you want to push the body towards fatty acid metabolism and in such a situation carnitine can be good. Then again if your body is used to running mainly on carbs and you are not trying to lose weight then a large dose of carnitine can cause strong unpleasant reactions, starting with cold extremities and everything else you could expect when starting a fast and forcing the body towards fatty acid energy source.
     
  3. Douglas Ek

    Douglas Ek Member

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    What about these studies?

    Carnitine versus androgen administration in the treatment of sexual dysfunction, depressed mood, and fatigue associated with male aging. - PubMed - NCBI
    Evidence for a positive association between serum carnitine and free testosterone levels in uremic men with hemodialysis. - PubMed - NCBI
    L-carnitine protects against testicular dysfunction caused by gamma irradiation in mice. - PubMed - NCBI
    Effects of L-carnitine and L-acetyl-carnitine on testicular sperm motility and chromatin quality
    Androgenic responses to resistance exercise: effects of feeding and L-carnitine. - PubMed - NCBI
    https://www.ncbi.nlm.nih.gov/pubmed/16169400

    Theres a lot more studies on carnitines effect on sperm parameters and also testosterone receptors and testosterone. If it increases all sperm parameters its probably due to increase in the androgen receptors and sensitivity? Ive only seen benefits when ive taken it.

    Wouldnt it be food on a high saturated fat diet to push that fat towards testosterone synthesis or at least in the sense of some saturated fats like palmitic acids positive boosting effect on testosterone and cells. Thinking carnitine and gonadin if carnitine could boost the fatty acids effects or basically any other fat soulable fatty acid pushing it into cells
     
  4. RWilly

    RWilly Member

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    Studies reveal role of red meat in gut bacteria, heart disease development
    https://medicalxpress.com/news/2018-12-reveal-role-red-meat-gut.html

    "In another study, published today in the Journal of Clinical Investigation, Dr. Hazen and his research team revealed a potential new target for preventing cardiovascular disease by drilling deeper into a gut microbial pathway that converts carnitine into TMAO.

    The researchers found that carnitine—a nutrient abundant in red meat and some energy drinks and supplements—is converted to TMAO in the gut through a two-step process facilitated by distinct gut bacteria. The team discovered that the first step is similar in both omnivores (meat eaters) and vegans/vegetarians. But in the second part, the formation of TMAO is significantly enhanced in omnivores. Researchers then went on to show that a daily carnitine supplement can induce TMAO production, even for vegans and vegetarians who continue eating their normal diets. Earlier this year, Dr. Hazen and his team published a study showing how researchers had designed a potential new class of drugs for prevention of heart disease and clotting risk by interrupting the microbial pathway by which choline is converted into TMAO.
     
  5. Douglas Ek

    Douglas Ek Member

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    Well if you dont eat meat then youll eat fish which is a larger source of TMAO. If you go vegan you eat a lot of PUFA. So best option is still tp eat meat. And I don’t buy TMAO danger anyway.
     
  6. High_Prob

    High_Prob Member

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    This is really interesting. Can anyone add any insight into what is going on here (Carnitines effects on Androgens)?
     
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