Kuinone - Liquid Vitamin K2 (MK-4)

[nicholebowden]

Over the last year a number of people on the forum asked me to release a vitamin K2 supplement as an alternative to the popular (but expensive) Thorne K2 supplement. So, I finally got around to delivering on my promise. Kuinone is a liquid dietary supplement with menatetrenone (MK-4) dissolved in ethanol and SFA esters. If you are wondering what's up with the weird name, well it is a play on the fact that vitamin K is a naphthoquinone, or a type of (q)uinone just like the well-known CoQ10. So, I combined the K from vitamin K and the word quinone to form Kuinone. Hopefully, it is not too confusing to people what the word means.
The fact that it is dissolved in SFA esters + ethanol mixture should dramatically improve topical absorption and allow a much lower daily dose to be used, which will make the bottle last much longer and thus further decrease the overall cost.
Finally, while the bone benefits of vitamin K2 are known to many people on the forum, some of its "niche" effects are not widely known. So, I compiled a (long) list of references broken down by categories for the people who are interested in finding out more about this amazing substance.

Note: This product contains raw material(s) meant for external use only, in cosmetic or other formulations designed for such external use.

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Kuinone is a dietary supplement containing vitamin K2 (MK-4) also known as menatetrenone. This product, while consisting entirely of food-grade ingredients, is sanctioned for external use only.

Servings per container: about 720
Serving size: 1 drop
Each serving contains the following ingredients:

Vitamin K2 (MK-4): 2 mg

Other ingredients: add product to shopping cart to see info
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References:

General
Highly recommended dose of MK4 for osteoporosis. - PubMed - NCBI
Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy. - PubMed - NCBI
Vitamin E and K interactions--a 50-year-old problem. - PubMed - NCBI
Pleiotropic actions of vitamin K: protector of bone health and beyond? - PubMed - NCBI
Exocrine pancreatic secretion of phospholipid, menaquinone-4, and caveolin-1 in vivo. - PubMed - NCBI
Improvement of vitamin K status of breastfeeding infants with maternal supplement of vitamin K2 (MK40). - PubMed - NCBI
Antinociceptive effect induced by intraperitoneal administration of vitamin K2 (menatetrenone) in ICR mice. - PubMed - NCBI
Effect of dietary fat content on oral bioavailability of menatetrenone in humans. - PubMed - NCBI
Effect of food composition on vitamin K absorption in human volunteers. - PubMed - NCBI
Distribution of menaquinone-4, a therapeutic agent for osteoporosis, in bone and other tissues of rats. - PubMed - NCBI


Bone Health
Treatment of glucocorticoid-induced low bone mineral density in children: a systematic review. - PubMed - NCBI
Low-dose menaquinone-4 improves γ-carboxylation of osteocalcin in young males: a non-placebo-controlled dose-response study. - PubMed - NCBI
Vitamin K2 improves femoral bone strength without altering bone mineral density in gastrectomized rats. - PubMed - NCBI
Vitamin K₂ therapy for postmenopausal osteoporosis. - PubMed - NCBI
Vitamin K-dependent carboxylation of osteocalcin affects the efficacy of teriparatide (PTH(1-34)) for skeletal repair. - PubMed - NCBI
Menatetrenone versus alfacalcidol in the treatment of Chinese postmenopausal women with osteoporosis: a multicenter, randomized, double-blinded, do... - PubMed - NCBI
Effects of vitamin K in postmenopausal women: mini review. - PubMed - NCBI
Menatetrenone for the treatment of osteoporosis. - PubMed - NCBI
Prevention of bone loss in children receiving long-term glucocorticoids with calcium and alfacalcidol or menatetrenone. - PubMed - NCBI
Amelioration of pregnancy-associated osteoporosis after treatment with vitamin K₂: a report of four patients. - PubMed - NCBI
Clinical results of alendronate monotherapy and combined therapy with menatetrenone (VitK₂) in postmenopausal RA patients. - PubMed - NCBI
Bridging the gap between osteoporosis and osteonecrosis of the jaw: preventing and treating BRONJ with MK4. - PubMed - NCBI
Vitamin K supplement along with vitamin D and calcium reduced serum concentration of undercarboxylated osteocalcin while increasing bone mineral de... - PubMed - NCBI
The prevention of hip fracture with menatetrenone and risedronate plus calcium supplementation in elderly patients with Alzheimer disease: a random... - PubMed - NCBI
Effect of vitamin K2 on cortical and cancellous bone mass and hepatic lipids in rats with combined methionine-choline deficiency. - PubMed - NCBI
Effect of GGCX gene polymorphism on the responses of serum undercarboxylated osteocalcin and bone turnover markers after treatment with vitamin K2 ... - PubMed - NCBI
Effects of long-term vitamin K(1) (phylloquinone) or vitamin K(2) (menaquinone-4) supplementation on body composition and serum parameters in rats. - PubMed - NCBI
Vitamin K₂ alters bone metabolism markers in hemodialysis patients with a low serum parathyroid hormone level. - PubMed - NCBI
Effects of vitamin K2 on cortical and cancellous bone mass, cortical osteocyte and lacunar system, and porosity in sciatic neurectomized rats. - PubMed - NCBI
Vitamin K2 promotes bone healing in a rat femoral osteotomy model with or without glucocorticoid treatment. - PubMed - NCBI
Effects of combination treatment with alendronate and vitamin K(2) on bone mineral density and strength in ovariectomized mice. - PubMed - NCBI
Prevention of hip fractures by exposure to sunlight and pharmacotherapy in patients with Alzheimer's disease. - PubMed - NCBI
Vitamin K to prevent fractures in older women: systematic review and economic evaluation. - PubMed - NCBI
Vitamin K promotes mineralization, osteoblast-to-osteocyte transition, and an anticatabolic phenotype by {gamma}-carboxylation-dependent and -indep... - PubMed - NCBI
Efficacy of menatetrenone (vitamin K2) against non-vertebral and hip fractures in patients with neurological diseases: meta-analysis of three rando... - PubMed - NCBI
Comparison of the effect of vitamin K(2) and risedronate on trabecular bone in glucocorticoid-treated rats: a bone histomorphometry study. - PubMed - NCBI
Collagen-related abnormalities, reduction in bone quality, and effects of menatetrenone in rats with a congenital ascorbic acid deficiency. - PubMed - NCBI
Prior treatment with vitamin K(2) significantly improves the efficacy of risedronate. - PubMed - NCBI
Short-term menatetrenone therapy increases gamma-carboxylation of osteocalcin with a moderate increase of bone turnover in postmenopausal osteoporo... - PubMed - NCBI
Vitamin K treatment reduces undercarboxylated osteocalcin but does not alter bone turnover, density, or geometry in healthy postmenopausal North Am... - PubMed - NCBI
Randomized controlled study on the prevention of osteoporotic fractures (OF study): a phase IV clinical study of 15-mg menatetrenone capsules. - PubMed - NCBI
Vitamin K2, a gamma-carboxylating factor of gla-proteins, normalizes the bone crystal nucleation impaired by Mg-insufficiency. - PubMed - NCBI
[Treatment of primary osteoporosis with vitamin K2]. - PubMed - NCBI
[Vitamin K metabolism. Menaquinone-4 (MK-4) formation from ingested VK analogues and its potent relation to bone function]. - PubMed - NCBI
Vitamin K2 induces phosphorylation of protein kinase A and expression of novel target genes in osteoblastic cells. - PubMed - NCBI
Vitamin K induces osteoblast differentiation through pregnane X receptor-mediated transcriptional control of the Msx2 gene. - PubMed - NCBI
Vitamin K2 supplementation improves hip bone geometry and bone strength indices in postmenopausal women. - PubMed - NCBI
Menatetrenone (vitamin K2) and bone quality in the treatment of postmenopausal osteoporosis. - PubMed - NCBI
Beneficial effect of pretreatment and treatment continuation with risedronate and vitamin K2 on cancellous bone loss after ovariectomy in rats: a b... - PubMed - NCBI
Infrared analysis of bones in magnesium-deficient rats treated with vitamin K2. - PubMed - NCBI
[Active vitamin D and vitamin K as therapeutic agents for osteoporosis]. - PubMed - NCBI
[Diabetic osteopahty and vitamin K]. - PubMed - NCBI
[Therapeutic approaches for diabetic osteopahty]. - PubMed - NCBI
Vitamin K2 treatment for postmenopausal osteoporosis in Indonesia. - PubMed - NCBI
Geranylgeranylacetone inhibits formation and function of human osteoclasts and prevents bone loss in tail-suspended rats and ovariectomized rats. - PubMed - NCBI
Comparative effects of vitamin K and vitamin D supplementation on calcium balance in young rats fed normal or low calcium diets. - PubMed - NCBI
[The interplay of magnesium and vitamin K2 on bone mineralization]. - PubMed - NCBI
[Vitamin K2 and bone quality]. - PubMed - NCBI
[Vitamin K2 (menatetrenone) and bone quality]. - PubMed - NCBI
Effects of vitamin K2 administration on calcium balance and bone mass in young rats fed normal or low calcium diet. - PubMed - NCBI
Menatetrenone rescues bone loss by improving osteoblast dysfunction in rats immobilized by sciatic neurectomy. - PubMed - NCBI
RETRACTED: Menatetrenone and vitamin D2 with calcium supplements prevent nonvertebral fracture in elderly women with Alzheimer's disease. - PubMed - NCBI
Vitamin K2 inhibits glucocorticoid-induced bone loss partly by preventing the reduction of osteoprotegerin (OPG). - PubMed - NCBI
Effects of vitamin K2 (menatetrenone) and alendronate on bone mineral density and bone strength in rats fed a low-magnesium diet. - PubMed - NCBI
Histochemical evaluation for the biological effect of menatetrenone on metaphyseal trabeculae of ovariectomized rats. - PubMed - NCBI
Effects of vitamin K2 in hemodialysis patients with low serum parathyroid hormone levels. - PubMed - NCBI
Vitamin K2 and geranylgeraniol, its side chain component, inhibited osteoclast formation in a different manner. - PubMed - NCBI
Protective effect of vitamins K2 and D3 on prednisolone-induced loss of bone mineral density in the lumbar spine. - PubMed - NCBI
Menatetrenone ameliorates reduction in bone mineral density and bone strength in sciatic neurectomized rats. - PubMed - NCBI
Treatment with vitamin D3 and/or vitamin K2 for postmenopausal osteoporosis. - PubMed - NCBI
Menatetrenone (vitamin K2) acts directly on circulating human osteoclast precursors. - PubMed - NCBI
High serum levels of menatetrenone in male patients with ossification of the posterior longitudinal ligament. - PubMed - NCBI
Effect of menatetrenone (vitamin K2) treatment on bone loss in patients with anorexia nervosa. - PubMed - NCBI
Effect of vitamin K2 on cortical and cancellous bones in orchidectomized and/or sciatic neurectomized rats. - PubMed - NCBI
Vitamin K stimulates osteoblastogenesis and inhibits osteoclastogenesis in human bone marrow cell culture. - PubMed - NCBI
Effect of vitamin K2 on cortical and cancellous bones in orchidectomized young rats. - PubMed - NCBI
Pharmacodynamics of menatetrenone and effects on bone metabolism in continuous ambulatory peritoneal dialysis patients. - PubMed - NCBI
Vitamin K2 (menatetrenone) inhibits bone loss induced by prednisolone partly through enhancement of bone formation in rats. - PubMed - NCBI
Menatetrenone prevents osteoblast dysfunction in unilateral sciatic neurectomized rats. - PubMed - NCBI
[Effect of menatetrenone (V.K2) on bone mineral density and bone strength in Ca/Mg deficient rats]. - PubMed - NCBI
Time-dependent effects of vitamin K2 (menatetrenone) on bone metabolism in postmenopausal women. - PubMed - NCBI
Maintenance of trabecular structure and bone volume by vitamin K(2) in mature rats with long-term tail suspension. - PubMed - NCBI
Amelioration of osteoporosis by menatetrenone in elderly female Parkinson's disease patients with vitamin D deficiency. - PubMed - NCBI
A comparison of alfacalcidol and menatetrenone for the treatment of bone loss in an ovariectomized rat model of osteoporosis. - PubMed - NCBI
Vitamin K2 (menatetrenone) for bone loss in patients with cirrhosis of the liver. - PubMed - NCBI
Effects of phenytoin and/or vitamin K2 (menatetrenone) on bone mineral density in the tibiae of growing rats - PubMed
Effects of vitamin K2 (menatetrenone) on calcium balance in ovariectomized rats - PubMed
Efficacy and safety of Menatetrenone-4 postmenopausal Thai women - PubMed
Vitamin K administration to elderly patients with osteoporosis induces no hemostatic activation, even in those with suspected vitamin K deficiency - PubMed
Effect of menatetrenone on bone mineral density and incidence of vertebral fractures in postmenopausal women with osteoporosis: a comparison with the effect of etidronate - PubMed
Effects of vitamin K on calcium and bone metabolism - PubMed
Inverse correlation between the changes of lumbar bone mineral density and serum undercarboxylated osteocalcin after vitamin K2 (menatetrenone) treatment in children treated with glucocorticoid and alfacalcidol - PubMed
Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis - PubMed
[Effects of vitamin K2 administration in the patients with severely motor and intellectual disabilities: assessment of bone metabolic marker and bone mineral density] - PubMed
Vitamin K(2) inhibits adipogenesis, osteoclastogenesis, and ODF/RANK ligand expression in murine bone marrow cell cultures - PubMed
Effect of vitamin K2 on three-dimensional trabecular microarchitecture in ovariectomized rats - PubMed
Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis - PubMed
Short-term effect of vitamin K administration on prednisolone-induced loss of bone mineral density in patients with chronic glomerulonephritis - PubMed
Menatetrenone plus alfacalcidol treatment for bone problems in eight children with skeletal unloading - PubMed
[Vitamin K2 (menatetrenone) treatment increased bone strength in rats given low-calcium diets] - PubMed
http://www.ncbi.nlm.nih.gov/pubmed/10446758
Use of vitamin K2 (menatetrenone) and 1,25-dihydroxyvitamin D3 in the prevention of bone loss induced by leuprolide - PubMed
A longitudinal study of the effect of vitamin K2 on bone mineral density in postmenopausal women a comparative study with vitamin D3 and estrogen-progestin therapy - PubMed
[Effects of a vitamin K2 preparation in severely handicapped patients complicated by osteopenia] - PubMed
http://www.ncbi.nlm.nih.gov/pubmed/9737352
http://www.ncbi.nlm.nih.gov/pubmed/9076586
http://www.ncbi.nlm.nih.gov/pubmed/8939773
http://www.ncbi.nlm.nih.gov/pubmed/7756045
http://www.ncbi.nlm.nih.gov/pubmed/7821350
http://www.ncbi.nlm.nih.gov/pubmed/7927067
http://www.ncbi.nlm.nih.gov/pubmed/8089928
http://www.ncbi.nlm.nih.gov/pubmed/8155403
http://www.ncbi.nlm.nih.gov/pubmed/8371513
http://www.ncbi.nlm.nih.gov/pubmed/1530637

Inflammation
http://www.ncbi.nlm.nih.gov/pubmed/8240383
http://www.ncbi.nlm.nih.gov/pubmed/8511981


Cardiovascular disease (CVD)
http://www.ncbi.nlm.nih.gov/pubmed/23344475
http://www.ncbi.nlm.nih.gov/pubmed/18234293
http://www.ncbi.nlm.nih.gov/pubmed/14654717
http://www.ncbi.nlm.nih.gov/pubmed/9414028
http://www.ncbi.nlm.nih.gov/pubmed/9247360

Diabetes
http://www.ncbi.nlm.nih.gov/pubmed/21136047
http://www.ncbi.nlm.nih.gov/pubmed/11325029

Kidney Health
http://www.ncbi.nlm.nih.gov/pubmed/22080166

Cancer
http://www.ncbi.nlm.nih.gov/pubmed/23225445
http://www.ncbi.nlm.nih.gov/pubmed/23191943
http://www.ncbi.nlm.nih.gov/pubmed/21661384
http://www.ncbi.nlm.nih.gov/pubmed/21410069
http://www.ncbi.nlm.nih.gov/pubmed/22870131
http://www.ncbi.nlm.nih.gov/pubmed/21163409
http://www.ncbi.nlm.nih.gov/pubmed/21109972
http://www.ncbi.nlm.nih.gov/pubmed/20569983
http://www.ncbi.nlm.nih.gov/pubmed/19639210
http://www.ncbi.nlm.nih.gov/pubmed/19550077
http://www.ncbi.nlm.nih.gov/pubmed/19501932
http://www.ncbi.nlm.nih.gov/pubmed/18251162
http://www.ncbi.nlm.nih.gov/pubmed/17404108
http://www.ncbi.nlm.nih.gov/pubmed/17399847
http://www.ncbi.nlm.nih.gov/pubmed/17376044
http://www.ncbi.nlm.nih.gov/pubmed/16400650
http://www.ncbi.nlm.nih.gov/pubmed/11925874
http://www.ncbi.nlm.nih.gov/pubmed/11807630
http://www.ncbi.nlm.nih.gov/pubmed/10865985
http://www.ncbi.nlm.nih.gov/pubmed/10641439
http://www.ncbi.nlm.nih.gov/pubmed/9827941
http://www.ncbi.nlm.nih.gov/pubmed/9177427
https://www.glowm.com/pdf/Book-OvarianCancerTherapeutics-CC-BY-Ch13.pdf




Neurological Health
http://www.ncbi.nlm.nih.gov/pubmed/24108469
http://www.ncbi.nlm.nih.gov/pubmed/23682563
http://www.ncbi.nlm.nih.gov/pubmed/20092997
http://www.ncbi.nlm.nih.gov/pubmed/19235890
http://www.ncbi.nlm.nih.gov/pubmed/14704312

Testosterone
http://www.ncbi.nlm.nih.gov/pubmed/21914161
http://www.ncbi.nlm.nih.gov/pubmed/21894328

Estrogen
http://www.ncbi.nlm.nih.gov/pubmed/15763078

Can you consume it orally or only by the skin ?

 

[Gipzy2u]

Do you have to take it with fat and vit D at the same time, do they work better together, im trying to
get calcium out of my arteries and what to take to soften arteries as ive been told i have hardening
of the arteries

 

[SuperStressed]

Do you have to take it with fat and vit D at the same time, do they work better together, im trying to
get calcium out of my arteries and what to take to soften arteries as ive been told i have hardening
of the arteries

Take it with fat but separately from Vitamin D to maximise absorption, take your D 4 hours apart just to be sure. Personally I do a few drops orally and a few drops topically just to make sure I've got the bases covered.

 

[UG Krishnamurti]

Take it with fat but separately from Vitamin D to maximise absorption, take your D 4 hours apart just to be sure. Personally I do a few drops orally and a few drops topically just to make sure I've got the bases covered.

I think you should separate VIT K from VIT E and not from VIT D.
I think they work synergistically.

 

[SuperStressed]

I think you should separate VIT K from VIT E and not from VIT D.
I think they work synergistically.

Think it was consumerlab that showed you absorb half the vitk if you take with D but all of the D. Don't quote me on that but I read that somewhere.

 

[jaype]

@haidut do you know if applying kuinone to the skin of a fracture help the bone heal faster?

 

[Mauritio]

Check this out , they actually increased the drops per container and the amount of k2 in each drop!!
I checked my receipt from 2018 the price is still the same .
Awesome company !

 

[stephenszt2]

Just received my Kuinone today. Looking forward to trying this! Plan is start with 2 drops and see how my body reacts. Going to apply to the navel at night. Went through about the first 15 pages of this thread

 

[brocktoon]

Just received my Kuinone today. Looking forward to trying this! Plan is start with 2 drops and see how my body reacts. Going to apply to the navel at night. Went through about the first 15 pages of this thread

Two drops is fine, but I wouldn't hesitate to begin with five. Then again, I'm not aware of any you're trying it...In any case, it's hard to overdo MK4.

 

[Mossy]

Just received my Kuinone today. Looking forward to trying this! Plan is start with 2 drops and see how my body reacts. Going to apply to the navel at night. Went through about the first 15 pages of this thread

Will you be using this topically or orally? Just curious. As for me, to give a purely non-scientific account, it seems to thicken the blood (so to speak). What it's actually doing, I do not know. But, maybe a blood thinner will counter that. I've been doing 2 drops on the navel the last month, on and off, but just last week I noticed that effect I've mentioned, by way of hemorrhoid, or hemorrhoid-like symptoms. Normally I've only experienced that when taking it orally.

 

[Sulcuscentralis]

Just received my Kuinone today. Looking forward to trying this! Plan is start with 2 drops and see how my body reacts. Going to apply to the navel at night. Went through about the first 15 pages of this thread

My experience it messed with my sleep if I used it before bed.

 

[stephenszt2]

Two drops is fine, but I wouldn't hesitate to begin with five. Then again, I'm not aware of any you're trying it...In any case, it's hard to overdo MK4.

Yeah I plan on upping the dosage as I figure out how I feel while taking it. Just from reading the earlier parts of the forum, seems like this was a more bioavailable version so I didn’t want to overdue it as some of the people experienced anxiety, ikdolnis

Will you be using this topically or orally? Just curious. As for me, to give a purely non-scientific account, it seems to thicken the blood (so to speak). What it's actually doing, I do not know. But, maybe a blood thinner will counter that. I've been doing 2 drops on the navel the last month, on and off, but just last week I noticed that effect I've mentioned, by way of hemorrhoid, or hemorrhoid-like symptoms. Normally I've only experienced that when taking it orally.

I will be applying it to the navel for now. Georgi had mentioned that navel application could be beneficial for a more systemic effect. I also have aspirin that I plan on taking if the blood thickening becomes a problem.

My experience it messed with my sleep if I used it before bed.

I’ve seen from the forum that some people experienced insomnia and some people have experienced drowsiness and improved sleep. I ended up getting 9 hours last night - while it wasn’t uninterrupted, I’m pretty happy about that.

I’m looking forward to really experimented with this. Maybe some time I’ll try it in the morning and see how I feel.

 

[equipoise]

This product is amazing. Teeth are extremely strong and white. Breathing is deep. It also makes me more stress resilient. Alĺ in all top product

 

[Mossy]

This product is amazing. Teeth are extremely strong and white. Breathing is deep. It also makes me more stress resilient. Alĺ in all top product

Would you mind sharing your routine with this supp: dose, frequency, method of application, and any concurrent supps that help? I ask because it's hard for me to find long term success with this. I don't always feel bad on this, but I definitely can, especially with oral usage. Thanks.

 

[Sagitarrius90]

Haidut mentioned fda says no shelf life of 12 months. I got my kunione in Jan 2021 and it says it expired in May 2021. It's June and im still using. I assume I'm good to go? Anyone used expired kunione? With haidut saying 12 months half life and it's been 6 that I'm okay just seeing if anyone else had an experience like this

 

[Mauritio]

Haidut mentioned fda says no shelf life of 12 months. I got my kunione in Jan 2021 and it says it expired in May 2021. It's June and im still using. I assume I'm good to go? Anyone used expired kunione? With haidut saying 12 months half life and it's been 6 that I'm okay just seeing if anyone else had an experience like this

Idealabs products last way longer than they say on The bottle . In using a 3 year old kuinone bottle and a 2 year old lisuride and they still work .

 

[equipoise]

Would you mind sharing your routine with this supp: dose, frequency, method of application, and any concurrent supps that help? I ask because it's hard for me to find long term success with this. I don't always feel bad on this, but I definitely can, especially with oral usage. Thanks.

I dose 3 times a day because of K2's short half life, squeezing a couple of drops in my navel. That's it, I spend most of my free time playing music almost completely naked on the beach or reading literature. I think vitamin D and K are very complimentary. If I happen to eat a fatty meal with it, I'm happy. I don't obsess about it though. I've seen only positives from Kuinone. As I said, teeth and breathing capacity are biggest changes I've seen. Teeth just have that squeeky clean feeling as if I've just brushed them and it never fades. White as pearls. Probably the best idealabs product.

 

[TheBeard]

I dose 3 times a day because of K2's short half life, squeezing a couple of drops in my navel. That's it, I spend most of my free time playing music almost completely naked on the beach or reading literature. I think vitamin D and K are very complimentary. If I happen to eat a fatty meal with it, I'm happy. I don't obsess about it though. I've seen only positives from Kuinone. As I said, teeth and breathing capacity are biggest changes I've seen. Teeth just have that squeeky clean feeling as if I've just brushed them and it never fades. White as pearls. Probably the best idealabs product.

Would any liquid vitamin K product in the navel have the same effect?
Or is there something to Haidut's?

 

[Mossy]

I dose 3 times a day because of K2's short half life, squeezing a couple of drops in my navel. That's it, I spend most of my free time playing music almost completely naked on the beach or reading literature. I think vitamin D and K are very complimentary. If I happen to eat a fatty meal with it, I'm happy. I don't obsess about it though. I've seen only positives from Kuinone. As I said, teeth and breathing capacity are biggest changes I've seen. Teeth just have that squeeky clean feeling as if I've just brushed them and it never fades. White as pearls. Probably the best idealabs product.

Thank you for the added detail. I thought I had read that the half-life of K2 is 3 days, but maybe it's 3 hours, which would make sense with your routine.

 

[Sulcuscentralis]

Thank you for the added detail. I thought I had read that the half-life of K2 is 3 days, but maybe it's 3 hours, which would make sense with your routine.

MK4 has a short half life. MK7 form has a longer hl.