I experience the same reaction.
Positives are : I got an productive kind of energy the first day. Another good thing is I look leaner and my skin looks super good. Libido is also up.
All after 2 days .
But i also experience bad mood ,irritable ,anxious ,depressed ,out of breath and sneezing often after I take Kuinone. If its irritating the gut those could be symptoms of high serotonin ?! But even taken topically it reaches the gut after some time , in a less concentrated way of course so I dont really know what to do . Would love to be able to take it .
Vitamin K can raise CO2 and that can lead to feeling of being out of breath. It can also raise GABA and that can have paradoxical effects such as irritability and bad mood, similar to allopregnanolone (a potent GABA agonist).
Allopregnanolone - Wikipedia
"...Increased levels of allopregnanolone can produce paradoxical effects, including negative mood, anxiety, irritability, and aggression.[29][30][31] This appears to be because allopregnanolone possesses biphasic, U-shaped actions at the GABAA receptor – moderate level increases (in the range of 1.5–2 nM/L total allopregnanolone, which are approximately equivalent to luteal phase levels) inhibit the activity of the receptor, while lower and higher concentration increases stimulate it.[29][30] This seems to be a common effect of many GABAAreceptor positive allosteric modulators.[26][31] In accordance, acute administration of low doses of micronized progesterone (which reliably elevates allopregnanolone levels) has been found to have negative effects on mood, while higher doses have a neutral effect.[32]"