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Kuinone - Liquid Vitamin K2 (MK-4)

Discussion in 'IdeaLabs' started by haidut, Jan 11, 2016.

  1. A.R

    A.R Member

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    Did you use to take the the aspirin exact same time as the vitamin k, or were the dosages split?
     
  2. sladerunner69

    sladerunner69 Member

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    Same time, typically. Shouldn't matter though.
     
  3. A.R

    A.R Member

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    @sladerunner69
    Ok that's interesting, I always thought both should not be taken together. I will start combining the two aswell because I get bad effects from aspirin on it's own.
     
  4. Kayo

    Kayo Member

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    @haidut
     
  5. OP
    haidut

    haidut Member

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    I already answered your PM.

    "...Most people apply to shoulders, forearms, wrists, legs or even top of feet. There is really no best body area for application but applying on larger areas closer to the torso makes more of the vitamin available systemically. Usually, applying closer to problematic spots tends to deliver more of the vitamin to those spots. So, the best application spot is a balance of what you want to affect more - systemic health or local issues. Most people put the drops on their skin and then rub with their index finger until it is well applied, but it does not have to rubbed in until dry. It dries out anyways within 5min and after that clothing can be put on top."
     
  6. BrianF

    BrianF Member

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    Wouldn't mind reading your response to that question..(or cluster of questions).. Its something i have been thinking a lot about recently. Unless theres anything personal or private, of course.
     
  7. OP
    haidut

    haidut Member

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    I edited my original response above with the PM.
     
  8. BrianF

    BrianF Member

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    Thks dude
     
  9. baccheion

    baccheion Member

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    The osteoporosis study that found 45 mg to be the minimum (after trying 15, 30, 45, 90, etc) was conducted on women weighing 45 kg. That is, to have the minimum effective dose scale to various weights, it would be better to use the rule 45 mg / 45 kg or 1 mg/kg. For a 70 kg person (154 lbs), 70 mg+ would be taken (split into 3 doses) or 75 mg as 15 mg pills are commonly used.
     
  10. Kayo

    Kayo Member

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    @haidut
    So I was applying some on my brow ridge and I wasn't paying much attention and accidentally dropped a few on my eyeball. It burned for a few minutes but I tried to wash it away. Made me really panic. Is this something to worry about?
     
  11. OP
    haidut

    haidut Member

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    Correct, and studies with prostate cancer do mention the 1mg/kg dose as optimal. However, the 45mg daily dose has been used on osteoporotic or osteopenic males who weighed more than 45kg and it still had positive effect.
     
  12. OP
    haidut

    haidut Member

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    Not really, it is the alcohol that causes that burning feeling. I would not apply to the eyes for that reason but other than the alcohol and its burning effects there is nothing else in Kuinone of potential concern. So, unless you have a severe reduction in vision lasting for more than 2-3 days it shouldn't be a cause of worry.
     
  13. Sajid

    Sajid Member

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    @haidut Can i use kuinone and estroban together ? As in estroban at the morning and kuinone at night , if I am right have seen that there is a limit if u take vitamin e and k2 together.
     
  14. OP
    haidut

    haidut Member

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    Yes, you can use them together but like you said - best to take them hours apart due to the vitamin E/K interaction.
     
  15. Arrade

    Arrade Member

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  16. baccheion

    baccheion Member

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  17. Janelle525

    Janelle525 Member

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  18. jb116

    jb116 Member

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    There were no control groups, so one can only guess at the effects of K in that case. They don't know if K was still actually helping against adverse events
    since without controls there is no reference to effects i.e. the outcomes for example could have been worse without K. Also, more importantly there might be a time issue here, as in not enough allotted. Since the Rotterdam study that I think Masterjohn spoke about regarding K2, followed subjects for 15+ years and high intake of vitamin K2 was associated with lower risks of severe aortic calcification, cardiovascular disease/disease mortality.
     
  19. Arrade

    Arrade Member

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    I agree control groups weren’t there. But as for time it was administrated ED for a year, in a methodology shown effective for osteoporosis. Intuitively it doesn’t make a lot of sense that Mk4 is good for arteries if a year at a high dose they are in worse condition (14% increase in CAC)
    My issue with saying K2 is that could mean any of the analogues. It’s not specifying Mk4, K2 could mean the consumption of Mk7 or mk9. And thus just supplementing mk4 might not be providing arterial benefit
     
  20. jb116

    jb116 Member

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    Compared to 15+ years, I think the time issue is the most relevant thing here. That coupled with lack of control seems limiting in potentially observing true beneficial effects. Past that amount of time, perhaps the conclusion would be initial increases in CAC and then a gradual tapering down. That would start to look like the Rotterdam study, where the ultimate effect was very beneficial for subjects.
     
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