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Ketotifen (Zaditen)

Discussion in 'Pharmaceutical Drugs' started by managing, Oct 21, 2014.

  1. managing

    managing Member

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    Anybody know anything about?
     
  2. haidut

    haidut Member

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    It's an antihistamine with a chemical structure very similar to Benadryl and cyproheptadine. There are some studies showing it helps people with IBS, but other than that it seems it would be no different than taking over the counter Benadryl (diphenhydramine). It's probably best if some people who have taken it chime in with some first-hand reports.
     
  3. Pointless

    Pointless Member

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    I have some Ketotifen Fumarate that I'm considering taking. I'm interested in its TNF-Alpha lowering, anti-serotonin, and mast cell stabilization. It comes in 1 mg tablets. I currently take Cyproheptadine 1 mg twice a day. I'm hoping to see if it can replace Cyproheptadine. Anyone have any guidance on dosage? I'm looking for comparable anti-serotonin effects to the dose of Cyproheptadine I'm taking.
     
  4. haidut

    haidut Member

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    Actually, I'd stay away from ketotifen. It seem to powerfully promote NO synthesis, which would negate many of its other benefits especially when taken long run. Cypro and Benadryl are much better, and even as little as 1mg cypro should have antiserotnin and antihistamine effect.
     
  5. Pointless

    Pointless Member

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    I stopped taking it anyway. It didn't antagonize serotonin as well as Cyproheptadine.
     
  6. DaveFoster

    DaveFoster Member

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    It has the fewest side effects I've ever seen from any drug:

    "Side effects include drowsiness, weight gain, dry mouth, irritability, and increased nosebleeds."[10]

    Ketotifen - Wikipedia
     
  7. debored13

    debored13 Member

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    i'll be keeping this in mind, especially since my doctor is considering mast cell stabilizers for my high IgE
     
  8. LCohen

    LCohen Member

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    I used it for 2 months. At first it was healing my gut/digestion, since it's a TLR4 antagonist. Now it's doing nothing for me. Not helping for sleep, digestion or anything.
     
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