1. Cocoa Butter - Organic & Fair Trade Certified
    CLICK HERE!
    Dismiss Notice
  2. **NEW** BL11 - Orange, Red & Infrared Therapy Body Light
    CLICK HERE!
    Dismiss Notice
  3. Charcoal Soap - For Deep Cleansing
    CLICK HERE!
    Dismiss Notice
  4. Orange & Red Light Therapy Device - LGS1
    CLICK HERE!
    Dismiss Notice
  5. Organic Cocoa Powder
    CLICK HERE!
    Dismiss Notice
  6. Metabasoap - Handcrafted Soap
    CLICK HERE!
    Dismiss Notice
  7. Cascara Sagrada Powder From Farmalabor In Italy
    CLICK HERE!
    Dismiss Notice
  8. **NEW Mini Body Light** MBL1 - Orange & Red Light Therapy Mini Body Light
    CLICK HERE!
    Dismiss Notice

Keloids - Trying To Understand Its Nature

Discussion in 'Skin' started by yerrag, Jul 21, 2017.

  1. Such_Saturation

    Such_Saturation Member

    Joined:
    Nov 26, 2013
    Messages:
    7,364
    This is very interesting. I wonder what would cause the dehydration of disk cartilage in old age. I actually am looking for some methods to reverse this at the moment.
     
  2. achillea

    achillea Member

    Joined:
    Feb 29, 2016
    Messages:
    441
    Gender:
    Male
    My wife had a kiloid develop over her lip which was so tight that it caused a deformation of the upper lip. Needless to say she was quite upset as she was still in her 40's and quite pretty. She had it abraided, did not work. Then when Dr Klinghardt was practicing in Sante Fe we went to see him for some prolotherapy and he suggested the use of the bee venom. I would say he injected it 3-5 times every 3-6 weeks and the keloid totally disappeared, A casual observer would never know she ever had it.

    I would venture that Sophia Health Clinic in Washington state would do it and if not, then know where to get it done as this is Klinghardts clinic and he has used bee venom for various reasons for decades.

    The bee venom is very high in hyaluronic acid, thus the reason I suggested its use. It is readily available. It may be advisable to start applying it topically to soften them up before the injections because the hardness of the keloid is like wire.
     
  3. Mito

    Mito Member

    Joined:
    Dec 10, 2016
    Messages:
    1,297
  4. OP
    yerrag

    yerrag Member

    Joined:
    Mar 29, 2016
    Messages:
    3,132
    Gender:
    Male
    Location:
    Manila
    I don't understand how plastic surgery would have solved it, unless the plastic surgeon is very skilled as well in dealing with keloids. After repeated surgeries that kept making it worse, Keith must have good reason to believe it will work this last time.
     
  5. OP
    yerrag

    yerrag Member

    Joined:
    Mar 29, 2016
    Messages:
    3,132
    Gender:
    Male
    Location:
    Manila
    I'm glad your wife got to see a very good doctor. Amazing Dr. Klinghardt!

    Bees and silkworm - letting nature do its work!
     
  6. OP
    yerrag

    yerrag Member

    Joined:
    Mar 29, 2016
    Messages:
    3,132
    Gender:
    Male
    Location:
    Manila
    I was rubbing two drops daily each of Tyromix (thyroid), StressNon (pregnenolone), and Progestene (progesterone) on my keloid for a week. A week after, I noticed a part of it turned soft and white. What do you think happened here? which of the three hormones caused the keloid to soften? Or is it a combination of two of these? Or all three together? I've never seen my keloid soften this way, by topical application.
     
  7. ivy

    ivy Member

    Joined:
    Mar 18, 2017
    Messages:
    119
    Gender:
    Female
    Location:
    Portugal
    No wonder I got terrible scars on my scalp then. I had some sebaceous cysts removed and now I'm left with even harder bumps from the scarring.

    @yerrag, any updates? Are you still using anything topically?
     
  8. OP
    yerrag

    yerrag Member

    Joined:
    Mar 29, 2016
    Messages:
    3,132
    Gender:
    Male
    Location:
    Manila
    I had to stop applying the hormones because they were increasing my blood pressure. Since blood pressure is my priority concern, I had to stop.

    Until recently though, I had recurring seborrheic dermatitis. I gave up on it, having had it for close to twenty years. Then, it went away. I think it had to do with my supplementation with therapeutic levels of magnesium, and with increased potassium intake. This was also to lower my blood pressure, but it resolved my scalp condition.

    Funny how things work out.
     
  9. OP
    yerrag

    yerrag Member

    Joined:
    Mar 29, 2016
    Messages:
    3,132
    Gender:
    Male
    Location:
    Manila
    I may have found a cause for keloids, at least in my case. It has to do with endotoxins and with how it disturbs the process of healing of scar tissue.

    I may have a longstanding case of periodontal bacterial infection that was hidden. This could date back to the early 90s, the time when I started to have keloids develop. I believe that the endotoxins were making my blood vessels permeable, and when I have a wound, the endotoxins would accompany the blood as it heals the wound. With the endotoxins also forming a clot along with fibrin, the healing matrix would be fibrinotic and would spur the formation of excess collagen around the scar. It also did not help that I was hypotoxemic before, the result of mercury toxicity, and the healing site was not healing properly due to a deficiency of oxygen.

    I draw from a study Capture of Lipopolysaccharide (Endotoxin) by the Blood Clot: A Comparative Study , where it explains the capture of LPS by blood clots:

    In addition to the passive entrapment of microbes invading at wound sites, the present report provides evidence for an active participation of the clot in immunity by its ability to capture and sequester the important microbial toxin, lipopolysaccharide (LPS, endotoxin). LPS is the principal lipid of the outer lamella of the outer membrane of Gram-negative bacteria[7] and is continuously shed into the environment by populations of these bacteria. Because lipid A, the central component of LPS, is a major agent of morbidity and mortality in humans and arthropods that experience infection by Gram-negative bacteria[8], [9], immunologists are interested in the systems for its inactivation and sequestration[10], [11]. We find that the extracellular fibrin clot and the platelet thrombus of the mammalian clotting system both bind LPS, as does the extracellular coagulin clot of the horseshoe crab, Limulus polyphemus, and the VHDL clot of the American lobster. It is suggested that the capture of LPS by the blood clot serves to reduce the dissemination of LPS released by Gram-negative bacteria that become entrapped in the clot following wounding of the integument, thus reducing the possibility that LPS from that source could cause systemic disease.

    While the effect of the capture of LPS by blood clots is salutary, given that it is a way to contain the systemic harm from LPS, I believe it could also result in the formation of keloid (Bleeding, clotting, cancer ) :

    Clots are formed when soluble fibrinogen polymerizes, condenses, and becomes insoluble. Even before the particles of fibrin become insoluble, a clot-dissolving system is continuously breaking it down into small peptides. These peptides tend to cause capillaries to leak. If a massive amount of fibrinogen and fibrin leak out of capillaries, clots are formed outside capillaries, and the peptides released in the process of cleaning up this debris contribute to further leakage, and to inflammation. The inflammation stimulates the production of collagen-rich connective tissue, and a fibrotic tissue replaces the functional tissues. Many of Hans Selye’s experiments explored the conditions in which inflammation, exudation, and fibrosis developed, sometimes ending with calcification of the region.

    The presence of fibrin in the extracellular matrix interferes with the differentiated functioning of cells, which depend on their contact with a normal matrix. When healing and regeneration occur in the normal matrix, the remodeling of the tissue involves the breakdown of collagen, which releases peptides with antiinflammatory, antiangiogenic and antiinvasive actions. When fibrin is present, the remodeling process releases peptides that increase cell growth, invasiveness, inflammation, and the production of new blood vessels, which in turn become leaky.

    I'm not sure if I'm tying things together right, but I get the sense that endotoxin causes fibrin leakage, and this state would characterize the way that a wound heals. The wound would be fibrotic, and unable to differentiate as it grows, much like a tumor would. That my hypotoxemic condition limits the availability of oxygen also contributes to further thickening the collagen layer of the healed wound.

     
  10. General Orange

    General Orange Member

    Joined:
    Apr 8, 2018
    Messages:
    1,142
    Gender:
    Male
    Location:
    The Netherlands
Loading...