Is this study about vitamin A most likely a lie to protect the use of isotretinoin?

[GorillaHead]

So apparently large doses of vitamin A is not effective for acne ? But isotretinoin is ?

definitely a lie right ? Oral vitamin A in acne vulgaris. Preliminary report - PubMed


Also obviously this study a decade earlier claims differently [Optimal dosage in peroral therapy of acne with vitamin A palmitate] - PubMed



How could the human body even need that much vitamin A to fix acne. That makes no sense to me.

 

[kierkegaardian]

The older studies/reports indicate that super high vitamin A in fact works safely for acne:

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onlinelibrary.wiley.com

Oral Vitamin A (Retinol) in Acne Vulgaris

The use of oral vitamin A in the management of acne has been controversial. In 1943, Straumfjord reported that 79 of 100 patients treated with 100,000 I.U. daily were completely cleared or nearly so after six months of therapy (20). Furthermore, only three patients...

link.springer.com