Is it possable for people to react differently between Benzodiazapines?

[troubledtimes]

i took an SNRI for 10 solid years which helped but seemed to conk out. im trying a zoloft now and using klonopin to help stabalize me until a medication works. the problem is 0.5 or even 1.5 mg of klonopin i notice basically nothing in the way of my anxiety calming down. however if i take 1mg of ativan/Lorazapam than i deffinitley feel it but its pretty short lived and you get these bad panic attacks once its out of your system. my diagnosis is Major depressive disorder, Generalized anxiety disorder and deffinitley some OCD. im debating maybe i should try valium? or maybe a little bit of klonopin and a little bit of ativan until a find a suitable medication that will work. i have tried alot of natural and lifestyle so im keeping this thread medication based. some people just need it. i am open to getting vitamin D tested which i dont know what it costs and even tho my thyroid says im ok i am willing to mess around with thyroid supplimentation