vetiver
Member
- Joined
- May 22, 2016
- Messages
- 49
I’ve recently started taking inosine (initially for its immunomodulatory effects) and have been experiencing profoundly positive effects on metabolism and mood. The first time I took it I had an experience that was comparable to LSD. Now, when I take it in the morning it induces very potent opioid effects and I feel mellow and euphoric during the day and then in the evening I get very energetic and all I want to do is dance and write poetry into the hours of the morning.
I’m overly cautious of anything that seems to good to be true, especially after my experience with tianeptine 2 yrs ago which had devastating effects on my health that I never recovered from. I get confused about receptor down regulation/upregulation, receptor density etc. I’m pretty sure I don’t do well on any substance taken chronically because of these negative feedback mechanisms. Things like cypro and most idealabs supplements give me bad rebound effects if taken for more than a few days.
Seeing as inosine is an opioid and gaba-a agonist, could this have potential side effects in the same way if taken long-term? Does desensitization always follow with things that act as agonists?
I’m overly cautious of anything that seems to good to be true, especially after my experience with tianeptine 2 yrs ago which had devastating effects on my health that I never recovered from. I get confused about receptor down regulation/upregulation, receptor density etc. I’m pretty sure I don’t do well on any substance taken chronically because of these negative feedback mechanisms. Things like cypro and most idealabs supplements give me bad rebound effects if taken for more than a few days.
Seeing as inosine is an opioid and gaba-a agonist, could this have potential side effects in the same way if taken long-term? Does desensitization always follow with things that act as agonists?
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