Inosine For The Treatment Of COVID-19

Discussion in 'Scientific Studies' started by haidut, Mar 15, 2020.

  1. haidut

    haidut Member

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    Just posting this one as an additional option for people who cannot tolerate methylene blue, anti-serotonin chemicals or large doses vitamin C. The drug used is available in Europe but plain inosine has been shown to work just as well so that would be the option for people in the US and other non-European countries. The treatment regimen was 1g inosine x 3 daily for 7 days.

    Inosine pranobex is safe and effective for the treatment of subjects with confirmed acute respiratory viral infections: analysis and subgroup analysis from a Phase 4, randomised, placebo-controlled, double-blind study
    "...The study results indicate the safety of inosine pranobex for the treatment of subjects with confirmed acute respiratory viral infections and confirm the efficacy of inosine pranobex versus placebo in healthy non-obese subjects less than 50 years of age with clinically diagnosed influenza-like illnesses."

    "...Acute respiratory infection is a serious infection that is responsible for approximately 3.9 million deaths per year and is one of the leading causes of morbidity and mortality worldwide [1]. Acute respiratory infections are categorized as either upper or lower respiratory infections and are caused by well-recognised viral pathogens, including but not limited to influenza virus (types A and B), parainfluenza virus, respiratory syncytial virus (RSV), metapneumovirus (types A and B), coronavirus, rhinovirus, enterovirus, reovirus, bocavirus, and adenovirus, and bacterial pathogens, primarily Streptococcus pneumoniae and Haemophilus influenza [2, 3]."
     
  2. ecstatichamster

    ecstatichamster Member

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    Thank you. Very useful.
     
  3. tupolev

    tupolev Member

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    > large doses vitamin C

    I'm 85% sure I had the WuFlu this week. I ran a fever for 3 days, was lethargic for four, and had a touch of pleurisy for five. I drank many cups of a tisane locally available to me called "berry beauty tea" which contains hibiscus and berries that provide a megadose of vitamin c. I generally spiked it with a touch of cognac and orange liquer (grand marnier), because why not.

    Did it matter? I dunno. I think it's just a flu. A rough week and then a normal person is fine.
     
  4. OP
    haidut

    haidut Member

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    Agreed, vitamin C is a great option especially if combined with methylene blue. Some people get bad digestive upset from it though but I think this mostly applies to supplement forms and not to natural sources like rosehip and other teas.
     
  5. Goat-e

    Goat-e Member

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    What sort of vitamin C dosage would be advisable with Methylene blue? I've fully down with MB but haven't got my head round the whole vit C thing...
     
  6. OP
    haidut

    haidut Member

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    Even 500mg per dose, when mixed with 1mg-2mg MB, should help. No need to down many grams per sitting, which increases the chance of GI upset and potentially making things worse.
     
  7. JanP

    JanP Member

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    Is it likely that Covid-19 would respond to inosine in the same way other coronaviruses does? It seems like Covid -19 is generally much more resistant than other coronaviruses.
     
  8. ddjd

    ddjd Member

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    do you think creatine would be of any benefit haidut?
     
  9. Velve921

    Velve921 Member

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    Any good sources anyone recommends for inosine?
     
  10. jb116

    jb116 Member

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    I've looked high and low and I can't find any without junk in it. There was one by gluten free remedies and they silently removed it fairly recently.
     
  11. Regina

    Regina Member

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  12. sladerunner69

    sladerunner69 Member

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  13. jb116

    jb116 Member

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  14. JanP

    JanP Member

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    Completely different molecule. Inositol is a B vitamin.
     
  15. Lewis Acid

    Lewis Acid Member

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  16. Mufasa

    Mufasa Member

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    I never heard Ray Peat talk about rosehip tea. Would you recommend it haidut? Im a bit cautious with all the herbs, as sometimes I later find out they are estrogenic or anti androgenic etc.
     
  17. dand

    dand Member

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    Very nice :)! Tranquilo!
     
  18. OP
    haidut

    haidut Member

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    The rosehips are the fruit and I have not seen any information about them being estrogenic. I think Ray did mentioned them a few times as a good source of vitamin C. When the LIGHT search engine was still operational I did searches for rosehip and it came up as discussions in some of his interviews.
     
  19. Broken man

    Broken man Member

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    Great one!!!
     
  20. akgrrrl

    akgrrrl Member

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    Dont worry too much about rosehips being anythjng but vitamjn C. After wild roses wilt and the rosehip fruit forms in September, I pick several pounds after a crisp night which really turns them sweet. The "seed" in each gets pinched out. I immediately line a piecrust with them packed tightly with beaten egg, cream cheese and brown sugar to bake for the best fall tart ever. The rest I divide for drying into tea and a batch of jam for the winter.
     
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