Improvement Of Cognitive Functions By Oral Intake Of Hericium Erinaceus. Lion's Mane

Discussion in 'Scientific Studies' started by Experienced, Oct 12, 2019.

  1. Experienced

    Experienced Member

    Feb 28, 2017
    Improvement of cognitive functions by oral intake of Hericium erinaceus. - PubMed - NCBI

    The method was basically followed by our previous test (30). In short, all participants were randomly divided into two groups: the H. erinaceus (HE) group taking four HE supplements in a day, and the placebo group taking four placebo supplements in a day that did not contain HE for 12 weeks. One HE supplement contained 0.8 g of the powdered fruiting body of HE and a placebo supplement did not contain any powder from HE. In our previous study, participants took cookies containing 2.0 g of HE for 4 weeks. However, in this study, we extended the duration to 12 weeks because we speculated that the improvement of cognitive functions needs longer time for remodeling nerve structure in brain.

    We carefully sorted the participants by following rules: we selected the participants who are over 50 years old, healthy, and agreed with joining in the test by their own will

    Hericium erinaceus has been recognized as medical mushroom since ancient time, but its scientific evidence for human health has been still uncertain. In this study, we tested a randomized, double-blind, placebo-controlled parallel-group comparative study to evaluate the improvement of the cognitive functions by taking supplements containing fruiting body of H. erinaceus for 12 weeks. We performed three kinds of tests: Mini Mental State Examination (MMSE), Benton visual retention test, and Standard verbal paired-associate learning test (S-PA). MMSE alone showed that oral intake of H. erinaceus significantly improved cognitive functions and prevented from the deterioration. We speculate that various chemical compounds, including hericenones, in the mushroom have multiple effects to the brain neural networks and improve cognitive functions. Oral intake of H.erinaceus is safe and convenient method for dementia prevention so far.

    Link to the study itself.