If You Had Both Testicles Removed, Would You Have To Take Testosterone?

[Westside PUFAs]

Testicular cancer, you get kicked in them too hard by an angry lover, you want to donate them to scientific research, whatever. What would happen? As I understand it, the only other place that testosterone is produced is in very small amounts in the adrenal glands but it's not enough.

"Effects after having both testicles removed

Some men are diagnosed with testicular cancer in both testicles. Or they may develop a second cancer in the other testicle, but this is rare. If this happens to you, you will need to have your other testicle removed. After the operation, you will no longer produce sperm or testosterone. So you will not be able to father a child unless you have sperm banking.

If you have had both testicles removed, you will have testosterone replacement therapy. This is necessary to give you a normal sex drive and so that you can get an erection. Low levels of testosterone can also cause mood changes and tiredness.

Testosterone replacement can be given by

Injection
Skin patches
Skin gel

Tablets are not very well absorbed, so tablets are not often used these days. Injections work well. You can have them into the muscle of your arm or leg every 2 to 3 weeks. Some research has shown that the levels of the hormone in your blood are more stable if you have injections at least every 2 weeks. If the levels are not stable, you can have mood changes, tiredness and loss of your sex drive between injections.

Skin patches are the newest way to give testosterone replacement. They are like plasters that give a small dose of testosterone through the skin all the time. They have very few side effects (just mild skin irritation in some men) and keep the testosterone levels very stable in your blood. Or your doctor may suggest you use a testosterone gel which you rub on to your skin every day."

http://www.cancerresearchuk.org/about-c ... lar-cancer

What's the point of having a sex drive with no testicles? How could you still have sex with no testicles? How could you still orgasm without sperm? And if you take exogenous testosterone, don't you risk converting a lot of that into estrogen?

 

[haidut]

Yes, you would.

Testicular cancer, you get kicked in them too hard by an angry lover, you want to donate them to scientific research, whatever. What would happen? As I understand it, the only other place that testosterone is produced is in very small amounts in the adrenal glands but it's not enough.

"Effects after having both testicles removed

Some men are diagnosed with testicular cancer in both testicles. Or they may develop a second cancer in the other testicle, but this is rare. If this happens to you, you will need to have your other testicle removed. After the operation, you will no longer produce sperm or testosterone. So you will not be able to father a child unless you have sperm banking.

If you have had both testicles removed, you will have testosterone replacement therapy. This is necessary to give you a normal sex drive and so that you can get an erection. Low levels of testosterone can also cause mood changes and tiredness.

Testosterone replacement can be given by

Injection
Skin patches
Skin gel

Tablets are not very well absorbed, so tablets are not often used these days. Injections work well. You can have them into the muscle of your arm or leg every 2 to 3 weeks. Some research has shown that the levels of the hormone in your blood are more stable if you have injections at least every 2 weeks. If the levels are not stable, you can have mood changes, tiredness and loss of your sex drive between injections.

Skin patches are the newest way to give testosterone replacement. They are like plasters that give a small dose of testosterone through the skin all the time. They have very few side effects (just mild skin irritation in some men) and keep the testosterone levels very stable in your blood. Or your doctor may suggest you use a testosterone gel which you rub on to your skin every day."

http://www.cancerresearchuk.org/about-c ... lar-cancer

What's the point of having a sex drive with no testicles? How could you still have sex with no testicles? How could you still orgasm without sperm? And if you take exogenous testosterone, don't you risk converting a lot of that into estrogen?

No, in all likelhood you can get away with not taking testosterone but one of its precursors. There are numerous studies on PubMed (with rodents) showing adrenals and peripheral tissues can synthesize testosterone just fine from precursors like pregnenolone and/or DHEA. There is a specific study with castrated male rodents showing suplemental pregnenolone allowed them to function and synthesize testosterone just fine, albeit with reduced plasma levels of the hormone. However, peripheral tissue levels (which is what matters anyways) were similar to those of control animals.
Of course, supplementing pregnenolone or DHEA won't solve the sterility issue since sperm is only produced in testicles.

 

[dd99]

And what would happen if a child lost his testicles, playing sports etc? Would they need testosterone supplementation to develop normally?

 

[Westside PUFAs]

And what would happen if a child lost his testicles, playing sports etc? Would they need testosterone supplementation to develop normally?

Great question.

 

[Jayfish]

Most likely you would want to take HRT alon with a solid aromatase inhibitor if you wanted to continue having manly features and an ability to get an erection. You do not need testicles to orgasm but you would probably have little to no ejaculate.