I Will Be Taking Cyproheptadine's Younger Brother - Pizotifen

[golder]

Definitely one to avoid. Appreciate your experimentation and putting your neck on the line in the name of science Lokzo.

 

[Basonh]

Today has been an ABSOLUTE NIGHTMARE....
I will update you all when I write a log of my experience on pizotifen. I literally feel like my IQ is 40 points lower than normal today.

thank you for your contribution

 

[TMCMac]

Interesting . Have you experimented with metergoline? Its also a serotonin antagonist. I also tried crypo and I felt so low mood it was kinda scary . I want to take it thought since I sense im a very high serotonin person especially when socializing I feel very inhibited nervous and awkward sometimes. But damn that post crypo was tough even at 1mg. I also dont like that it causes weight gain since I need to lose a lot of weight. I am doing 4mg metergoline for about 10 days now. Hopefully it does something similar.

 

[Lokzo]

Interesting . Have you experimented with metergoline? Its also a serotonin antagonist. I also tried crypo and I felt so low mood it was kinda scary . I want to take it thought since I sense im a very high serotonin person especially when socializing I feel very inhibited nervous and awkward sometimes. But damn that post crypo was tough even at 1mg. I also dont like that it causes weight gain since I need to lose a lot of weight. I am doing 4mg metergoline for about 10 days now. Hopefully it does something similar.

Haha yeah I know what you mean!

Keep us updated in this thread with your Metergoline experiments.

 

[Basonh]

Haha yeah I know what you mean!

Keep us updated in this thread with your Metergoline experiments.

Did you experience a Great rebound like cypro?

 

[Lokzo]

Did you experience a Great rebound like cypro?

I am still waiting. The problem is, that I had exposure to potatoe starch and/or ginger again, which usually crashes me for 3-4 days, that not even a cypro rebound can overcome. No rebound as of yet sadly. I want my 'money' back (Not literally).
Pizotifen is eliminated with a half life of approximately 23 hours (total radioactivity). Unchanged pizotifen and the N-glucuronide have, as estimated from the excretion in the urine, a comparable elimination half-life. In patients with kidney insufficiency, dosage adjustment may be necessary.
I have elevated β-glucuronidase actitivity as well, which would be delaying the excretion I would imagine.

 

[Smelly5]

How did this go

 

[Herbie]

@Lokzo have you tried taking cypro for a few months straight? Work up to 4mg and higher and higher? Just take maybe 12mg a day for 3 months or something like that.

Maybe it will take that to fully cure you instead of a short lived relief.

I took 1 gram of cypro over a year, made permanent changes to me.

 

[Brandin]

@Lokzo have you tried taking cypro for a few months straight? Work up to 4mg and higher and higher? Just take maybe 12mg a day for 3 months or something like that.

Maybe it will take that to fully cure you instead of a short lived relief.

I took 1 gram of cypro over a year, made permanent changes to me.

1gram

 

[Lokzo]

@Lokzo have you tried taking cypro for a few months straight? Work up to 4mg and higher and higher? Just take maybe 12mg a day for 3 months or something like that.

Maybe it will take that to fully cure you instead of a short lived relief.

I took 1 gram of cypro over a year, made permanent changes to me.

I would consider doing 4mg for 3-4 days in a row!

 

[brightside]

@Lokzo have you tried taking cypro for a few months straight? Work up to 4mg and higher and higher? Just take maybe 12mg a day for 3 months or something like that.

Maybe it will take that to fully cure you instead of a short lived relief.

I took 1 gram of cypro over a year, made permanent changes to me.

What did you notice? I have permanent changes as well.

 

[Mathgirl]

What kind of permanent changes

 

[Herbie]

What did you notice? I have permanent changes as well.

I've Taken 1 Gram Of Cyproheptadine Over 12 Months

Hi, Ive used OTC Periactin and tried dosages ranging from 1mg up to 36mg in one day. I chose to use it based on symptoms I had and felt that it would be beneficial. I used to be in a fog and had a hard time concentrating on achieving tasks and making decisions, unstable in my mind and reactive...

raypeatforum.com

 

[Frankdee20]

I did try it, but I felt more "Tense" and "Uptight" on it, kind of like it was ramping up norepinephrine and blocking GABA, which I could feel the anti-social effects.

Ginkgo does block glycine and gaba to an extent