How To Reduce Serotonin

[ddjd]

Methylene blue, Lisuride, vitex are some dopaminergic therapies that could reduce serotonin for some, but for someone with endotoxin or other serotonin overload issues, these are likely to make it worse. I believe that Lisuride has caused me some dopamine downregulation or serotonergic effects.

Spot on about methylene blue. It causes my Serotonin to increase.

Why do you say lisuride increases Serotonin?

 

[ddjd]

I would never recommend SSRI's to anyone as they are notoriously dangerous and I don't think you can naturally compensate for the increased serotonin. If you are facing depression my advice is to focus on increasing neurosteroids and dopamine receptor density- dopamine levels. In my experience the best thing for mood is increased androgens.

If youre facing depression reducing Serotonin is probably the best route!

 

[ddjd]

Can lower serotonin:
Thyroid/t3
Aspirin
Caffeine
Charcoal
Carrots
Bamboo shoots
Salt
Sugar
Progesterone
Antibiotics
Dopamine
Phenylalanine
Taurine
Glycine/gelatin
Tyrosine
Cyproheptadine/ periactin
Tianeptine
Bromocriptine
Vit d
Calcium
Pregnenolone 30-50mg a day
Phenibut
BCAA's
Ondansetron/ zofran
Lysine
Ginger
LSD
Niacinamide
Benadryl
Agmatine
Co2
Methylene Blue
Adequate protein
Acetazolamide
DMT
L-theanine
Black tea
Psilocybin mushrooms
Lisuride
Zinc
Medium and short chain fatty acids

Can increase serotonin;
Hypothyroidism
PUFAs
Starches and fibres
Too much b6
Wheat based foods
Anything that irritates bowels
Sunburn
Long term starvation
Endotoxin/ inflammation of intestine
Bananas, tomatoes, pineapple
Light deficiency
High Tryptophan
Low testosterone
High Nitric Oxide levels
Elevated cortisol
Protein deficiency
Too much water
MDMA
Whey protein
Estrogen

Signs of high serotonin;
Loose bowels
Autism
IBS
Lots of sweating
Anxiety
Nauseousness
Insomnia
Teeth grinding
Reduced appetite for salt
Asthma
Anorexia
Depression
High blood pressure
Irritability
Aggression

My list!!

 

[ddjd]

DHT also lowers most serotonin receptors but increases the good ones

There's good Serotonin receptors? How do you know which are good and bad

 

[ddjd]

charcoal, carrot, bamboo shoots lowering serotonin

They all lower endotoxin

 

[ddjd]

I've been taking 500mg Niacinamide once or twice a day. and gets severe diarrhea.
Is it a sign of low serotonin?

niacinamide has the opposite effect for me. Definitely lowers Serotonin

 

[Pointless]

Spot on about methylene blue. It causes my Serotonin to increase.

Why do you say lisuride increases Serotonin?

Lisuride is a mixed serotonin agonist/antagonist.

 

[Makrosky]

Can lower serotonin:
DMT

Really ? Why ? Do you have any sources for this ?

 

[ddjd]

Really ? Why ? Do you have any sources for this ?

i dont think its something you will be wanting to take regularly!!

 

[Makrosky]

i dont think its something you will be wanting to take regularly!!

No need to. Just once every few months. But I don't know why he claims DMT is antiserotonin.

 

[Sucrates]

Really ? Why ? Do you have any sources for this ?

No.
It was posted in a group, most of the list is good. I shouldn't have included that list without checking everything on it. The interactions with DMT and serotonin are extremely complicated.

@charlie would you remove that post, I can't seem to edit it.
How To Reduce Serotonin

 

[ddjd]

No need to. Just once every few months. But I don't know why he claims DMT is antiserotonin.

It's actually my list that he copied. To be honest, I did a search on the ray peat Facebook group and listed everything on there, there's no studies to back anything up

 

[Sucrates]

It's actually my list that he copied. To be honest, I did a search on the ray peat Facebook group and listed everything on there, there's no studies to back anything up

You'll never see a penny from the royalties @Joeyd

 

[marcar72]

Why no milk?

It's high in trypotophan, but taking bcaa's and tryosine with it will negate this.

I checked out the BCAA/tryptophan ratio of milk vs. meat and was amazed to find that meat has a significantly better amino acid profile in this regards. Peat has said that the amino acid profile of eggs are good, but feels there's too much PUFA which might offset the benefits.

So I personally have cut down on milk (quart/day max) and have started having 4 scrambled eggs/day and also try to have 1/2 pound of ground beef/day. The amino acid profile of this move is more beneficial than any worries about consuming too much PUFA. I also add cheese to the eggs/meat for additional protein.

Too much dairy I feel isn't really all that helpful and is actually quite harmful in the long run.

 

[ddjd]

Lisuride is a mixed serotonin agonist/antagonist.

I've been experimenting with lisuride. Seems to cause me headaches. Did you get that? But lisuride completely stops my hair shedding, I have healthy stools, whereas metergoline causes my hair to shed and loose stools

 

[EIRE24]

Niacinamide is hard on the stomach and can kill bacteria causing bacteria die off symptoms.

Does Niacinamide interfere with fat loss?

 

[Wagner83]

Does Niacinamide interfere with fat loss?

In my short-lived experience with it I'd say yes.

 

[ddjd]

Oftentimes lowering serotonin also lowers dopamine, and raising serotonin raises dopamine. This can explain a lot of the benefits that people receive from serotonergic therapies. Keep in mind that stuff like 5-htp is very hit or miss and can be a disaster for some people. I used to get hypomanic and very euphoric from 5-htp but it doesnt affect me like that anymore (it gives me abdominal pain).

I thought I read somewhere that Serotonin and Dopamine have more of a seesaw like relationship, so one up, one down

 

[Pointless]

I thought I read somewhere that Serotonin and Dopamine have more of a seesaw like relationship, so one up, one down

I wish it was that easy, but in my experience, it's much more complicated.

 

[Capt Nirvana]

Personally i d9nt fully understand the prescripton to lower serotonin when there is so much research to suggest that serotonin is the "happy" chemical. My friend qho uses 5htp to increase serotonin production says he feels great all day. I think stress hormones may contribute to degenerative conditions when being consistently relied upon, but generally are useful because they play a role in human psychology that gives us emotional drive and energy and important feelings and sensations. When i follow low serotonin protocol I will feel sometimes very borred and emotionless, like nothing in the world matters to me at all.

If serotonin was simply a bad thing, then why wouod it exist at all? It has to serve a purpose physiologically, towards the maintenence of good health.