How To Make Sure You Detox Estrogen Effectively

Discussion in 'Articles & Scientific Studies' started by Hans, Jul 27, 2020.

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  1. Hans

    Hans Member

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    Estrogen is detoxed through the liver. It gets conjugated with glucuronic acid which makes it easier to eliminate from the body. However, there is an enzyme in the body that re-activates the detoxed estrogen.

    I wrote a short article discussing how to inhibit that enzyme to allow proper estrogen (and other toxins) detoxification.
    How to make sure you detox estrogen properly » MenElite
     
  2. Regina

    Regina Member

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    Thanks Hans.
    Great article.
    I wonder if you have thoughts on kombucha (due to its glucoronic acid content). I used to feel amazing after a few ozs of booch. Then, there was a distinct switch where it made me feel horrible and I started gaining weight. Now I am thinking it could be from raised β-glucuronidase. Thx
     
  3. Inaut

    Inaut Member

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    D-limonene is something which I think is relevant to this subject @Hans
     
  4. LeeLemonoil

    LeeLemonoil Member

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    Any data on it inhibiting beta-glucuronidase?

    Another gem @Hans

    Goes to show once more that estrogens are foremost stress and inflammation steroids as part of the immune system and not a „female hormone“.
    Nf-Kb as on of the Master signalers of the inflamnatio-cascade frees up estrogens when bound to glucoronate so it can itself set up inflammation processes.
     
  5. Jessie

    Jessie Member

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    Good article. I'm becoming more and more interested in cardamom. After you told me it has a mild laxative effect, and now finding out it can reduce ammonia and lactate, it's sounding more and more like something to include on a regular and consistent basis.
     
  6. Inaut

    Inaut Member

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  7. Recoen

    Recoen Member

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    Have you tried calcium d glucarate?
     
  8. Vinny

    Vinny Member

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    Thank you, Hans
     
  9. Randle Cyclist

    Randle Cyclist Member

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    Great article, thanks. Milk thistle is amazing stuff. It might just be me but my alcohol tolerance and clearance rate skyrockets when I use it. That's a sign that it's doing something beneficial for the liver in my book.


    I had the exact same issue but the weight gain for me was water retention, likely from gut inflammation. I tried various brands and even made my own using yerba mate. Same end result. Made me constantly nauseated as well.
     
  10. Recoen

    Recoen Member

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    Is milk thistle beneficial for both phase I and II?
     
  11. OP
    Hans

    Hans Member

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    Thanks! It should be fine in small doses, so it's definitely good to stay at doses where you still feel fine. Kombucha's glucuronic content is lower than that of grapefruit and if you eat a whole grapefruit you should be getting much more glucuronic acid than from a little kombucha.
     
  12. OP
    Hans

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    Yes indeed, but I can't find anything on limonene and beta-glucuronidase, only for phase II detoxification.
     
  13. OP
    Hans

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    Thanks man. Yes indeed, the combination of elevated estrogen and inflammation is a nasty combo. But even "normal" estrogen with inflammation will be a problem.
     
  14. OP
    Hans

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    Try it out, see how it works for you and then give a small update here if you don't mind.

    Not as a supplement no.

    Thanks for reading. Good stuff. Taurine is also great and can speed up alcohol clearance from the liver as well which can help prevent hangover.
     
  15. OP
    Hans

    Hans Member

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    :hattip
     
  16. Broken man

    Broken man Member

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    I am taking glucoronolactone for this.
     
  17. OP
    Hans

    Hans Member

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    Nice. What doses and how does it make you feel?
     
  18. Broken man

    Broken man Member

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    I think Its good for circulation and mental resiliency but sometimes have headaches from it.
     
  19. Regina

    Regina Member

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    Thx Hans.
     
  20. Jessie

    Jessie Member

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    Will do! Seems like something that would synergize with thiamine and biotin really well. I've just started a high dose biotin experiment for the purposes of suppressing gluconeogenesis, so I think I'll add some cardamom to the stack.
     
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