How to lower Progesterone? and how long till supplemented Pregnenolone leaves my system?

fasoracetam

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Jan 29, 2021
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So supplementing Pregnenolone causes a lot of issues for me.
Mainly it causes low e2 symptoms which cant be fixed by raising testosterone dose, DHEA or anything else.

My last pregnenolone 100mg capsule was taken 4 days ago. I know the dose is too high but i also had problems with 10mg everyday.
When will I find relief, how long does it take for the pregnenolone and its conversion to progesterone to leave my body?

And is there anything I can do to lower progesterone manually, with any supplements or other meds?
 
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So supplementing Pregnenolone causes a lot of issues for me.
Mainly it causes low e2 symptoms which cant be fixed by raising testosterone dose, DHEA or anything else.

My last pregnenolone 100mg capsule was taken 4 days ago. I know the dose is too high but i also had problems with 10mg everyday.
When will I find relief, how long does it take for the pregnenolone and its conversion to progesterone to leave my body?

And is there anything I can do to lower progesterone manually, with any supplements or other meds?
What kind of problems did it give you fasoracetam? Many people are big on supplementing it, but I haven't done so.
 
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i had the same issues with high progesterone - i went overboard on it when i was new to Ray Peat stuff - it created a lot of issues for me. i ended up doing a lot of liver cleansing and taking Bi Est cream and stopped it all together. never again with mega progesterone for me .... ever ever ever.
 
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We are only just trying Progest-E this past couple of months. What kind of problems did you run into stargazer?
 
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weight gain , closed up cervix, grew a fibroid, constipation, messed up liver. by the time I got levels tested my progesterone was massively high. i knew my estrogen was low ish but hopped on the Peat Progesterone wagon because I thought that I had extra fat bc my "bmi " was high- but it turns out that I am super muscular so upon further testing, it turned out that I just weigh more bc of that. It f*ked me up sooo much. I know Peat thinks estrogen is the root of all evil but I do not agree. I was on Progest E for about a year or more.
 
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weight gain , closed up cervix, grew a fibroid, constipation, messed up liver. by the time I got levels tested my progesterone was massively high. i knew my estrogen was low ish but hopped on the Peat Progesterone wagon because I thought that I had extra fat bc my "bmi " was high- but it turns out that I am super muscular so upon further testing, it turned out that I just weigh more bc of that. it f*ked me up sooo much. i know Peat thinks estrogen is the root of all evil but I do not agree. I was on Progest E for about a year or more.
Oh geeze! That sounds like our scenerio, very muscular, but I thought it might cover some evening tequilas. I really don't have estrogens come from anywhere else. Do you think we should cut back or cut it out totally? I really don't know much about it to know how to gauge it. I was doing fine Peating the last 4+ years without it. We are mostly liking the deep sleep from it, otherwise I haven't noticed any other benefits yet.
 
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I would do a saliva hormone test to see where are hormone-wise. My experience is that bio-identical progesterone can build up quickly and trust me, having too much of it your system wreaks a special kind of hell scenario. Also , I do Bi - Est with Progesterone now and get the deepest sleep . I do not take it every day. It really depends on how old you are when where you are in the hormone thing. I started going crazy with progesterone when i had peri meno heavy bleeding and I swear I took so much that it stopped my period altogether. ( maybe ) I was pretty young when my periods stopped, but I was also 17 when I got my period so my hormone thing has always been weird. I would say test and then proceed , but dont think that progesterone is all fun and games. you need estrogen too . :)
 
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I would do a saliva hormone test to see where are hormone-wise. My experience is that bio-identical progesterone can build up quickly and trust me, having too much of it your system wreaks a special kind of hell scenario. Also , I do Bi - Est with Progesterone now and get the deepest sleep . I do not take it every day. It really depends on how old you are when where you are in the hormone thing. I started going crazy with progesterone when i had peri meno heavy bleeding and I swear I took so much that it stopped my period altogether. ( maybe ) I was pretty young when my periods stopped, but I was also 17 when I got my period so my hormone thing has always been weird. I would say test and then proceed , but dont think that progesterone is all fun and games. you need estrogen too . :)
Thanks for all that info! I think I will proceed on the side of caution and cut it way back.
 

august4

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Jun 11, 2021
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I would do a saliva hormone test to see where are hormone-wise. My experience is that bio-identical progesterone can build up quickly and trust me, having too much of it your system wreaks a special kind of hell scenario. Also , I do Bi - Est with Progesterone now and get the deepest sleep . I do not take it every day. It really depends on how old you are when where you are in the hormone thing. I started going crazy with progesterone when i had peri meno heavy bleeding and I swear I took so much that it stopped my period altogether. ( maybe ) I was pretty young when my periods stopped, but I was also 17 when I got my period so my hormone thing has always been weird. I would say test and then proceed , but dont think that progesterone is all fun and games. you need estrogen too . :)
I hopped on the progesterone wagon too, without knowing the consequences. Why is that never talked about? Only all the benefits? Now my cycle is seriously messed up. I think got the first time in my life I'm not ovulating. So went through a whole pregnancy scare. Just trying to figure this out now. If it is stored in our fat tissues, do I just need to wait it out and hope things go back to normal? I don't want to do labs. Oh you have any insights please share. Thank you!
 

June

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Any updates? Are you guys still taking progesterone with good results? How about starting with high doses and then backing down to low doses and staying there.
 

sunny

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I have been taking progest-e cyclical monthly for years. It reliable knocked out the monthly water retention and sore breast. Nothing but stellar results. I was also taking health Natura pregnenolone powder each morning, never noticed any benefits- but they might have been unnoticed because of the way that works, according to Ray. I may start pregnenolone again but in a topical. My labs don't show any increase in anything. I am in the weird space of not yet post menopause because a cycle will show up randomly. At this point I am a firm believer in Ray Peats view of progesterone for women.
 
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Any updates? Are you guys still taking progesterone with good results? How about starting with high doses and then backing down to low doses and staying there.
I put some on my lips occasionally, when I go out to a restaurant, and when I have been feeling anxiety it soothes me, but nothing else noticeable for me. I don’t have issues I guess to notice a difference from.
 

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