How To Increase Prostaglandin E1 And Lower E2

[AndrogenicKing]

Any advice on how to increase Prostaglandin E1 and lower E2?

 

[maillol]

Looks like alcohol would do it.

Fetal Alcohol Syndrome and Essential Fatty Acids

Ethanol (1) reduces blood linoleic acid (LA) levels; (2) blocks conversion of LA and gamma-linolenic acid (GLA) to arachidonic acid (AA), as well as alpha-linolenic acid (ALA) to eicosapentaenoic and docosahexaenoic acids (EPA and DHA, respectively), by inhibiting delta-6 and delta-5 desaturases; and (3) enhances the conversion of dihomo-gamma-linolenic acid (DGLA) to PGE1 [1].