How to increase it ? Is something like licorice root would bee helpful ?
Here is a little bit of context why would one want try this pathway. Although i am not affected by fin, but I have PAS, which symptomatically manifest itself exactly how it's described in this paper.
Here is a little bit of context why would one want try this pathway. Although i am not affected by fin, but I have PAS, which symptomatically manifest itself exactly how it's described in this paper.
The Steroidogenesis Inhibitor Finasteride Reduces the Response to Both Stressful and Rewarding Stimuli
Finasteride (FIN) is the prototypical inhibitor of steroid 5α-reductase (5αR), the enzyme that catalyzes the rate-limiting step of the conversion of progesterone and testosterone into their main neuroactive metabolites. FIN is clinically ...
www.ncbi.nlm.nih.gov
The effects of FIN on FST responses were associated with a dramatic decrease in corticotropin release hormone (CRH) mRNA and adrenocorticotropic hormone (ACTH) levels. These results suggest that FIN impairs stress reactivity and reduces behavioral activation and impulsive behavior by altering the function of the hypothalamus–pituitary–adrenal (HPA) axis.
It is also worth noting that, in addition to its effects on stress response, CRH enables arousal and behavioral activation, irrespective of stress
Third, by interfering with corticosterone degradation, FIN may enhance the levels of this hormone and potentiate its effects on the negative feedback regulation of CRH and ACTH synthesis