How much pregnenolone do adults endogenously manufacture?

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Feb 25, 2019
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I’m curious if anyone knows of any information pointing to the range of milligrams of pregnenolone men and women manufacture daily?

also, is there a diurnal pattern to its secretion during the course of the day?
@haidut
 

SonOfEurope

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Jul 10, 2016
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602
Around 30mg in a healthy 20's or 30's person.

I imagine production would be more optimal in a young animal that is not impacted by PUFA, has plenty of light and sugar because it's Cytochrome P450 and ultimately Mitochondria dependant.

It's the more downstream and more powerful hormones like Cortisol, Etradiol and Testosterone that have cycles - P5 is more constant.
 
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