1. Cocoa Butter - Organic & Fair Trade Certified
    CLICK HERE!
    Dismiss Notice
  2. **NEW** BL11 - Orange, Red & Infrared Therapy Body Light
    CLICK HERE!
    Dismiss Notice
  3. Charcoal Soap - For Deep Cleansing
    CLICK HERE!
    Dismiss Notice
  4. Orange & Red Light Therapy Device - LGS1
    CLICK HERE!
    Dismiss Notice
  5. Organic Cocoa Powder
    CLICK HERE!
    Dismiss Notice
  6. Metabasoap - Handcrafted Soap
    CLICK HERE!
    Dismiss Notice
  7. Cascara Sagrada Powder From Farmalabor In Italy
    CLICK HERE!
    Dismiss Notice
  8. **NEW Mini Body Light** MBL1 - Orange & Red Light Therapy Mini Body Light
    CLICK HERE!
    Dismiss Notice

How much more Levothyroxine to bring Free T3/T4 into the upper third of the range?

Discussion in 'T4' started by youngandold, Nov 17, 2015.

  1. youngandold

    youngandold Member

    Joined:
    Nov 17, 2015
    Messages:
    87
    Right now I'm taking 50 mcg of Levothyroxine every day.

    Free T3 and T4 are at about half of the normal range yet I feel like this isn't enough for me as I feel many HYPOthyroid symptoms like cold hands and feet, extreme fatigue, slow digestion.

    If I want to get Free T3 and Free T4 in the upper third of the range
    How much more Levothyroxine would I need?
    75 mcg daily? 100 mcg?

    I used to have naturally very high Free T3 with borderline low Free T4.
    So Levothyroxine alone might be optimum, thus not needing any T3.
     
  2. OP
    youngandold

    youngandold Member

    Joined:
    Nov 17, 2015
    Messages:
    87
    I used to have high (beyond normal range) Free T3 with borderline low Free T4 with very resistant high blood pressure, palpitations being very easily startled by sudden noises.

    A cardiologist prescribed Tapazole (an antithyroid drug) but it only lowered FT4 even more, TSH skyrocketed yet FT3 remains high.
    This caused extreme hyperthyroid symptoms.
    Like heat intolerance so extreme I couldn't even get out of the house or even wear any clothes inside the house despite fair weather.

    So this proves why adequate T4 is needed and why T3-only is a dangerous nonsense (never endorsed by Ray Peat by the way).

    It looks like Levothyroxine flipped the switch from fully hyper to a bit hypothyroid.
     
  3. OP
    youngandold

    youngandold Member

    Joined:
    Nov 17, 2015
    Messages:
    87
    Before taking Levothyroxine Free T4 was always borderline low (now mid range) while Free T3 was always high (now mid range).
    TSH now about 2.6

    So it looks like this is the right path.

    If I aim for both Free T3 and T4 to be in the upper third of the range and for TSH to be below 2 or even below 1 as Ray Peat advises then
    How much more Levothyroxine do I need to take?
    (Now on 50 mcg Levothyroxine)
     
  4. OP
    youngandold

    youngandold Member

    Joined:
    Nov 17, 2015
    Messages:
    87
  5. OP
    youngandold

    youngandold Member

    Joined:
    Nov 17, 2015
    Messages:
    87
    Long-term validity of biological markers of psychopathy and
    criminal recidivism: follow-up 6-8 years after forensic
    psychiatric investigation.

    Abstract
    This study is a follow-up investigation of a forensic psychiatric sub-
    population 6-8 years after forensic psychiatric evaluation. The aim
    was to examine the long-term validity of biological markers of
    psychopathy and antisocial behavior over time. Data on criminal
    records were obtained at follow-up from the National Council for
    Crime Prevention. Basic data included findings of psychiatric and
    psychological assessments, as well as values for serum
    triiodothyronine (T3) and free thyroxin (FT4), and platelet
    monoamine oxidase (MAO) activity, all obtained during the forensic
    psychiatric examination. Criminal recidivists at follow-up had higher
    serum T3 levels than non-recidivists, and much higher values than
    normal controls, while their levels of free T4 were lower. The T3
    levels in criminal recidivists correlated to psychopathy- and
    aggression-related personality traits as measured by the Karolinska
    Scale of Personality. In violent recidivists, a remarkably high
    correlation was noted between T3 levels and Irritability and
    Detachment, traits that have previously been linked to the
    dopaminergic system. Stepwise multiple regression analyses
    confirmed the relationships of T3 levels and platelet MAO activity
    with personality traits in criminal recidivists. The predictive validity
    of biological markers of psychopathy, T3 and platelet MAO,
    measured during forensic psychiatric investigation, is stable over
    time. The results indicate chronic alterations of the hypothalamic-
    pituitary-thyroid axis in this group of subjects.
     
  6. Jooce_user

    Jooce_user Member

    Joined:
    Nov 16, 2015
    Messages:
    5
    Can you please give an example of such erratic behavior?

    thanks
     
  7. Jooce_user

    Jooce_user Member

    Joined:
    Nov 16, 2015
    Messages:
    5
    tsh - .16 (0.40-4.50 mIU/L)
    t3 uptake - 32 (22-35)
    t3 free - 5.6 (2.3-4.2 pg/mL)
    t4 free - 1 (0.8-1.8 ng/dL)
    t3 reverse - 10 (8-25 ng/dL)

    @youngandold

    What do you make of this bloodwork? This was taken on 3.5 grains of thyroid
     
  8. OP
    youngandold

    youngandold Member

    Joined:
    Nov 17, 2015
    Messages:
    87
    Jooce user

    Hypomania, impulsiveness hypersexuality, grandiose ideas, trouble concentrating, etc.

    Free T4 is borderline low, FT3 is high and TSH is low.
    I had similar labs naturally.
    It is better to reduce NDT and add some Levothyroxine.

    I forgot to say that my thyroid ultrasound analysis spotted changes 'most likely caused by chronic acute thyroiditis'
     
  9. Jooce_user

    Jooce_user Member

    Joined:
    Nov 16, 2015
    Messages:
    5
    I would consider all of those things positive besides the trouble concentrating.

    I don't have much of a libido though, so I don't think I am in this category.

    How do you feel with more t4? Still energetic, but not manic?
     
Loading...