- Joined
- Oct 30, 2015
- Messages
- 819
Here @haidut posted a study showing 300 mg benforthiamine twice daily was shown to successfully treat diabetes.
Yet, on his recent, and very informative interview (Stuff your Doctor should know, Maintain your brain) he stated that benfothiamin, unlike allithiamine and fursultiamine, doesn't cross the Blood Brain Barrier (BBB). So how can it treat Alzheimer's (dementia / brain diabetes)?
Moreover, this paper here , suggests that even fursultiamine (as benfo) are unable to raise thiamin pyrophosphate (TPP) in the brain??? and yet the fursulthiamine is used to treat dementia in Japan?
so can these precursors of thiamin reach brain cells and convert into TPP or not?
Thiamin experts please weigh in.
Yet, on his recent, and very informative interview (Stuff your Doctor should know, Maintain your brain) he stated that benfothiamin, unlike allithiamine and fursultiamine, doesn't cross the Blood Brain Barrier (BBB). So how can it treat Alzheimer's (dementia / brain diabetes)?
Moreover, this paper here , suggests that even fursultiamine (as benfo) are unable to raise thiamin pyrophosphate (TPP) in the brain??? and yet the fursulthiamine is used to treat dementia in Japan?
so can these precursors of thiamin reach brain cells and convert into TPP or not?
Thiamin experts please weigh in.