Hormonal Treatment For Advanced Prostate And Breast Cancer

marciomega

Member
Joined
Jun 27, 2018
Messages
13
Hello all,

I´m new to this forum .I ´ve already read something about ray peat´s work but never dived deep into it. I´ve been researching on alternative cancer treatments for the last 4 years, since my mother and father have advanced prostate and breast cancers. I´ve be focusing lately on hormonal treatment for both, though I have covered dozens of other alternative treatments also. From plants like graviola to aloe arborecens, suplements like phosphoethanolamine, poly mva, curcumin , repurpused drugs, metabolic treatments and so on. Recently we took a chance on implanting Testosterone+Aromatase inhibitors pellets for my mom, and I studying the risks involved in trying testosterone for my father also.
I´d like to exchange ideas , experiences and studies , so that I can take the best decisions for them and perhaps help others in the same situation.
Is there anybody who can comment on this?
 

Obi-wan

Member
Joined
Mar 16, 2017
Messages
1,120
Testosterone fuels prostate cancer. If it is advanced he needs to be put on androgen depravation therapy asap
 

marciomega

Member
Thread starter
Joined
Jun 27, 2018
Messages
13
BAT- bipolar androgen therapy is already in clinical trials. The paradigma that texto fuels prostate câncer has been changed in the last decade

Effect of bipolar androgen therapy for asymptomatic men with castration-resistant prostate cancer: Results from a pilot clinical study

https://onlinelibrary.wiley.com/doi/full/10.1002/pros.22504

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(17)30907-5/fulltext?code=lancet-site

From bench to bedside: bipolar androgen therapy in a pilot clinical study

Not to mention other prostate câncer models that have been offered , like Edward Friedman´s Receptor´s model .

Articles on this subject can be easily goggled by anyone interested.
 

vulture

Member
Joined
Sep 1, 2017
Messages
1,018
I think main problem with testosterone might be aromatization.
There is a study on veins impairment where prostate was receiving abnormaly high androgen supply, specially Free-T (as surgeons stated) and correcting it reversed BPH. Would be a good idea to asses how veins are working. Look: https://www.google.com/search?q=gat+gorem+varicoceles&ie=utf-8&oe=utf-8&client=firefox-b-ab
They also said that exogenous T didn't impact significantly on the BPH because the abnormal androgen quantities that the prostate was receiving where dozens of times higher than the quantity it would receive by exogenous T.
If I had a bunch of rats with prostate cancer I would try Mesterolone to see what happens. There are no studies on it, but there are studies that shows that Mesterolone have improved LUTS (Lower Urinary Tract Symptoms) on elderly males. I haven't seen anything that, in vivo, demonstrates that DHT or Mesterolone had a negative impact on prostate health
 

Obi-wan

Member
Joined
Mar 16, 2017
Messages
1,120
My PSA hit 13,000, Firmagon saved my life...LH makes a testosterone pool, FSH converts it to estrogen. DHT causes proliferation in a cancer cell due to Polyamines...Firmagon stops LH and FSH.
 

marciomega

Member
Thread starter
Joined
Jun 27, 2018
Messages
13
Obi wan, my father is currently on firmagon and abiraterone. He first tried firmagon when his os was 1200. PSA lowered to 500 then started climbing again after only 2 months. The he entered abiraterone and his psa dropped to 230. Abiraterone not only knocks out any androgen made in adrenals but also glucorticoids , making a general mess in the body. His quality of life is terrible now, anemy, depression, fatigue and so on ....and it gets worse each day despite a falling psa level. I´m afraid the treatment might killl him instead of cancer...
 

Obi-wan

Member
Joined
Mar 16, 2017
Messages
1,120
Obi wan, my father is currently on firmagon and abiraterone. He first tried firmagon when his os was 1200. PSA lowered to 500 then started climbing again after only 2 months. The he entered abiraterone and his psa dropped to 230. Abiraterone not only knocks out any androgen made in adrenals but also glucorticoids , making a general mess in the body. His quality of life is terrible now, anemy, depression, fatigue and so on ....and it gets worse each day despite a falling psa level. I´m afraid the treatment might killl him instead of cancer...

I am on Xtandi also (might be better than abiraterone), look into it. Plus you must read Ted From Bangkok's Treatment Killing Cancer Cells Using Their Electricity, DMSO, Methylene Blue
 

LCohen

Member
Joined
Dec 31, 2017
Messages
257
Testosterone fuels prostate cancer. If it is advanced he needs to be put on androgen depravation therapy asap

Yes, easily aromatizable androgens fuels prostate cancer via estrogen.

Non-aromatizable androgens (Yes, DHT) treats it.
 

Obi-wan

Member
Joined
Mar 16, 2017
Messages
1,120
Yes, easily aromatizable androgens fuels prostate cancer via estrogen.

Non-aromatizable androgens (Yes, DHT) treats it.


But DHT creates prostaglandin E2 which creates Polyamines which create proliferation. The prostate is already a polyamine rich organ...
 

lampofred

Member
Joined
Feb 13, 2016
Messages
3,019
I read a thread on here a few weeks or months ago saying daily aspirin drastically lowered PSA. Daily coffee consumption also dose-dependently lowers prostate cancer risk by 3% or something per cup consumed. Another study on here states prostate cancer cannot progress in the absence of PUFA. I think the efficacy of high dose aspirin and coffee consumption proves that excessive estrogen relative to progesterone is the cause of prostate cancer, not excessive androgens. Peat's article on prostate cancer: Prostate Cancer
 

Obi-wan

Member
Joined
Mar 16, 2017
Messages
1,120
I read a thread on here a few weeks or months ago saying daily aspirin drastically lowered PSA. Daily coffee consumption also dose-dependently lowers prostate cancer risk by 3% or something per cup consumed. Another study on here states prostate cancer cannot progress in the absence of PUFA. I think the efficacy of high dose aspirin and coffee consumption proves that excessive estrogen relative to progesterone is the cause of prostate cancer, not excessive androgens. Peat's article on prostate cancer: Prostate Cancer
Androgens are great until you have prostate cancer...I got off of Firmagon last year and did high Progesterone. PSA went sky high again. Think Polyamines...
 
Last edited:

lampofred

Member
Joined
Feb 13, 2016
Messages
3,019
Androgens are great until you have prostate cancer...

Well, regardless of whether androgens or estrogens cause prostate cancer since we can't say anything with 100% certainty, the best course of action I think would be to avoid messing with either androgens or estrogens and instead just supplement massive amounts of pregnenolone and progesterone.
 

Obi-wan

Member
Joined
Mar 16, 2017
Messages
1,120
Well, regardless of whether androgens or estrogens cause prostate cancer since we can't say anything with 100% certainty, the best course of action I think would be to avoid messing with either androgens or estrogens and instead just supplement massive amounts of pregnenolone and progesterone.

And low PUFA and NO cell phone in your pocket...
 

Obi-wan

Member
Joined
Mar 16, 2017
Messages
1,120
Xtandi acts in the androgen receptor and don´t mess with the adrenals hormones but may have some important side effects...are you doing ok?
Yes, take it before bed every night. It makes you tired. Minimal side effects
 

marciomega

Member
Thread starter
Joined
Jun 27, 2018
Messages
13
I read a thread on here a few weeks or months ago saying daily aspirin drastically lowered PSA. Daily coffee consumption also dose-dependently lowers prostate cancer risk by 3% or something per cup consumed. Another study on here states prostate cancer cannot progress in the absence of PUFA. I think the efficacy of high dose aspirin and coffee consumption proves that excessive estrogen relative to progesterone is the cause of prostate cancer, not excessive androgens. Peat's article on prostate cancer: Prostate Cancer

I think Edward Friedman´s model kind of is aligned with Peat´s thoughts....

http://math.uchicago.edu/~ed/prostate.html
 

Obi-wan

Member
Joined
Mar 16, 2017
Messages
1,120

vulture

Member
Joined
Sep 1, 2017
Messages
1,018
But DHT creates prostaglandin E2 which creates Polyamines which create proliferation. The prostate is already a polyamine rich organ...
Obi, I admire your research and I follow it, there's nothing personal, but as long as I know there's no study on cancer in vivo and DHT. There's no way for us to know if "DHT causes proliferation in a cancer cell due to Polyamines..." ... in vivo
 

Obi-wan

Member
Joined
Mar 16, 2017
Messages
1,120
Obi, I admire your research and I follow it, there's nothing personal, but as long as I know there's no study on cancer in vivo and DHT. There's no way for us to know if "DHT causes proliferation in a cancer cell due to Polyamines..." ... in vivo
Maybe @Travis can tell us...
 
Similar threads
Thread starter Title Forum Replies Date
H Effects of Physical Activity at High Altitude on Hormonal Profiles in Foreign Trekkers and Indigenous Nepalese Porters Scientific Studies 0
Igorevich Strange hormonal profile Cholesterol 19
tankasnowgod The Anti-Catabolic and Anabolic Hormonal Profile of Eggs Eggs 28
Lokzo Morning After Pill For Hormonal Re-Set In Men?! Experiments 0
TopGun1911 Did I permanently alter my metabolic and hormonal function by going on keto for 3 months + fasting? Diet 25
L Severe Hormonal Imbalance Female Issues 2
GreekDemiGod Female Interactions & Hormonal Profile Ask For Help or Advice 38
A How To Solve Hormonal Acne Caused By Weightlifting ? Skin 14
TheBeard Lucas Parker's Hormonal Profile Hormones 43
Mito Melatonin: Master Hormonal Conductor And Scheduler Articles & Scientific Studies 4
2ManyHistamines Tests Needed For A View Into The Hormonal Profile Of Panic Attacks? Ask For Help or Advice 17
D Hormonal Issues Possibly Stemming From Aromatase Inhibitor Use(?) Male Issues 33
ScurveDream Theory: Older People More Likely To Die Because Of Serotonin/estrogen/hormonal Issues? Metabolism 4
Cdmiller2939 Hormonal Profile Causes A Man To Be Very Fat Yet Very Muscular And Strong? Body Care 37
H Hormonal Blood Tests I Got For Depression Blood Work, Labs 14
I Female Hormonal Issues, Question About Best Idealabs Ask For Help or Advice 19
K Reason For Fatigue And Hormonal Imbalance? Ask For Help or Advice 1
A KHABIB NURMAGOMEDOV (UFC) HORMONAL STATE Health 66
T Prostate Cancer, High Cortisol Levels And Complex Hormonal Interaction Scientific Studies 0
T Would Pansterone Correct Hormonal Imbalance Or Merely Masquerade It? Ask For Help or Advice 4
Lokzo 21 Y.O - Full Hormonal Results. Thoughts? Blood Work, Labs 22
D End Of My Rope, Very Distraught. Need Hormonal Experts Advice Ask For Help or Advice 21
ecstatichamster If Progesterone Makes My Penis Numb, What Does That Mean For My Hormonal Situation Male Issues 21
3 Post-Diet Hormonal Yield Diet 0
F Hormonal Imbalance? Female Issues 0
L Estrogen Receptor Activation By Tobacco Smoke Condensate In Hormonal Therapy-resistant Breast Cancer Scientific Studies 12
DuggaDugga Changes Of Thyroid Hormonal Status In Patients Receiving Ketogenic Diet Scientific Studies 3
S Maternal Nest-building Is Regulated By The Hormonal Actions Of Estradiol, Progesterone, And Prolacti Thyroid and Hormones 0
O How Can I Get A Healthy Hormonal Profile? Ask For Help or Advice 3
D What Is The Hormonal Profile Of A Man W/full Head Of Hair And A Hairy Body? Male Issues 13
J Hormonal Connection To Dopamine/Happiness/Mental Health Mental Issues 5
R Question About Hormonal Profile Ask For Help or Advice 0
scarlettsmum Women Over 35 Hormonal Changes, Are You Doing Anything? Female Issues 41
M Hormonal Blood Test Results - Need Advices Blood Work, Labs 0
nullredvector Nofap As Hormonal Deficiency, Addiction Misunderstood, And DHT Testimonials 59
P Hormonal Responses From Concentric And Eccentric Muscle Contractions Articles & Scientific Studies 2
Drareg Melanin Pigmentation In Mammalian Skin And Its Hormonal Regulation Scientific Studies 6
Ulla Hormonal combination of estradiol and norgestrel- pcos theraphy? Female Issues 29
M Hormonal Contraceptive Use And Risk Of Glioma Articles & Scientific Studies 1
T HORMONAL DIARRHEA? Digestion 30
G hormonal fluctuations Ask For Help or Advice 2
I Need help with hormonal acne Skin 23
md_a Treatment for COVID-19 using Methylene Blue Articles & Scientific Studies 3
R Acute COVID ARDS Treatment Ask For Help or Advice 0
haidut Rising use of methylene blue in India as COVID-19 prevention/treatment Health 19
charlie The treatment of small intestinal bacterial overgrowth with enteric-coated peppermint oil: a case report Scientific Studies 43
J Treatment for pericoronitis Oral Health 0
Pina Topical Lung T3 Treatment COVID-19 Acute Respiratory Distress Syndrome Thyroid and Hormones 0
haidut Androgens (e.g. DHT) curative even for treatment-resistant breast cancer Scientific Studies 0
Mito The efficacy of Vitamin K in the treatment of cancer K 1

Similar threads

Top