High-protein Diet Reduces Hepatic Fat Than Low-protein Diet

[meatbag]

It seems like some people are still eating low protein diets. Not ideal for liver health it seems

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Results: IHL levels decreased by 42.6% in the HP group, but were not significantly changed in the LP group despite similar weight loss. Hepatic autophagy flux and serum FGF21 increased by 66.7% and 42.2%, respectively, after 3 weeks in the LP group only. Expression levels of fat uptake and lipid biosynthesis genes were lower in the HP group compared with those in the LP group. RNA-seq analysis revealed lower activity of inflammatory pathways upon HP diet. Hepatic mitochondrial activity and expression of β-oxidation genes did not increase in the HP group.

Conclusions: HP diet more effectively reduces hepatic fat than LP diet despite of lower autophagy and FGF21. Our data suggest that liver fat reduction upon HP diets result primarily from suppression of fat uptake and lipid biosynthesis.
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via: https://twitter.com/UpToPhate

 

[Rinse & rePeat]

It seems like some people are still eating low protein diets. Not ideal for liver health it seems

--
Results: IHL levels decreased by 42.6% in the HP group, but were not significantly changed in the LP group despite similar weight loss. Hepatic autophagy flux and serum FGF21 increased by 66.7% and 42.2%, respectively, after 3 weeks in the LP group only. Expression levels of fat uptake and lipid biosynthesis genes were lower in the HP group compared with those in the LP group. RNA-seq analysis revealed lower activity of inflammatory pathways upon HP diet. Hepatic mitochondrial activity and expression of β-oxidation genes did not increase in the HP group.

Conclusions: HP diet more effectively reduces hepatic fat than LP diet despite of lower autophagy and FGF21. Our data suggest that liver fat reduction upon HP diets result primarily from suppression of fat uptake and lipid biosynthesis.
--
via: https://twitter.com/UpToPhate

Those people are still living by the old food pyramid meatbag. My dad's girlfriend bragged to me one morning that she got in her 20 grams of protein already by noon. When I was confused about that, she said that she read that a person needs 20 grams a day of protein. She is skeletal skinny with skin barely hanging on her bones. They call it "skinny fat".