High Estradiol, low Estrone? also viruses

Joined
Nov 26, 2013
Messages
7,367
Hello forum,

I have encountered, recently, high levels of Estradiol and low levels of Estrone in my blood for a male individual (43 pg/mL and 22 pg/ml, respectively). I have not been taking Pregnenolone or Progesterone recently. Do you have any suggestion regarding the cause of this? I'd say the pattern suggests the testosterone pathway is involved, but I'm not ready to rule out milk. Two quarts could give about 1500-2000 pg of Estradiol a day, resulting in a daily excess of 500 pg given a half life of 15 hours; over a month that would already be significant in my opinion (3 pg/mL of blood). Estrone should also be high, though.


I have also found late Cytomegalovirus, Zoster and Adenovirus antibodies; would you say it is a good idea to take some amount of Astragalus or Arabinogalactans to overstimulate the immune system? I know this be would hard on the body, as well as anti-Peat. C-reactive protein is very low (0.03mg/dL)

I am 22 and I have a history of mild anemia, neutropaenia, Tourette's like tics (triggered by feeding especially), candida, acne, gray patches and fatigue (gone). My diet consists of two quarts of pastured milk, juice, organ meats and seafood with T3 and T4. I have been stone cold lately! Do help me out, please.

Thank you, and be well.
 
Joined
Apr 21, 2013
Messages
176
I think excess milk and thyroid synergistically increase estrogen levels in susceptible individuals. There is a well known association between hyperthyroidism and elevated estrogen levels in men. It's important to note that estrogen can be elevated even without the classical signs of hyperthyroidism such as racing pulse and sweating. An over-reliance on milk inhibits the absorption of iron and zinc; a deficiency of either results in anemia and the latter a relative excess of copper.

Moderating the dose of thyroid and taking a zinc supplement ought to work. Zinc is very effective at firing up the immune system.
 

Mittir

Member
Joined
Feb 20, 2013
Messages
2,034
Daily Raw carrot salad should help with lowering estrogen.
RP puts a lot of emphasis on this.
A healthy liver supposed to detoxify all the estrogen passes through it.
RP thinks excess estrogen is a common cause of hypothyroidism.
Low thyroid, Low progesterone,PUFA storage, Gut irritation,
endotoxin and weak liver contributes to high estrogen.
High Estrogen and low thyroid creates a vicious cycle.
Pectin in OJ and other fruit juices can increase endotoxin.
It would be a good idea to avoid pectin and soluble fiber to see if things get better.
Measuring temperature and pulse 1-2 hour after breakfast gives a good idea
about thyroid status. If you can test your TSH, Total T3 an total T4, if possible reverse T3.
Too much fluid can be a problem for hypothyroid person. Extra salt can help with that
or you can decrease fluid consumption until your thyroid gets better.
In the beginning i mostly ate home made farmers' cheese .
You can drink 1 quart of milk and farmers cheese from 1 quart of milk.
RP thinks common cause of anemia is hypothyroidism.
You will need Iron saturation index and Ferritin level to
measure your total iron status.

There are old threads on estrogen in milk. RP recommended low fat milk if someone is worried about estrogen in milk. According to following study skim milk has 0.4 pg/ml and
1 percent milk has 0.6 pg/ml. It looks like you are using whole milk.
This study claims that estrogen in cow's milk is small compared to human production.

Dairy Sci. 2010 Jun;93(6):2533-40. doi: 10.3168/jds.2009-2947.
Estrone and 17beta-estradiol concentrations in pasteurized-homogenized milk and commercial dairy products.
Pape-Zambito DA, Roberts RF, Kensinger RS.
Source

Department of Dairy and Animal Science, The Pennsylvania State University, University Park 16802, USA.
Abstract

Some individuals fear that estrogens in dairy products may stimulate growth of estrogen-sensitive cancers in humans. The presence of estrone (E(1)) and 17beta-estradiol (E(2)) in raw whole cow's milk has been demonstrated. The objectives of this study were to determine if pasteurization-homogenization affects E(2) concentration in milk and to quantify E(1) and E(2) concentrations in commercially available dairy products. The effects of pasteurization-homogenization were tested by collecting fresh raw milk, followed by pasteurization and homogenization at 1 of 2 homogenization pressures. All treated milks were tested for milk fat globule size, percentages of milk fat and solids, and E(2) concentrations. Estrone and E(2) were quantified from organic or conventional skim, 1%, 2%, and whole milks, as well as half-and-half, cream, and butter samples. Estrone and E(2) were quantified by RIA after organic solvent extractions and chromatography. Pasteurization-homogenization reduced fat globule size, but did not significantly affect E(2), milk fat, or milk solids concentrations. Estrone concentrations averaged 2.9, 4.2, 5.7, 7.9, 20.4, 54.1 pg/mL, and 118.9 pg/g in skim, 1%, 2%, and whole milks, half-and-half, cream, and butter samples, respectively. 17Beta-estradiol concentrations averaged 0.4, 0.6, 0.9, 1.1, 1.9, 6.0 pg/mL, and 15.8 pg/g in skim, 1%, 2%, whole milks, half-and-half, cream, and butter samples, respectively. The amount of fat in milk significantly affected E(1) and E(2) concentrations in milk. Organic and conventional dairy products did not have substantially different concentrations of E(1) and E(2). Compared with information cited in the literature, concentrations of E(1) and E(2) in bovine milk are small relative to endogenous production rates of E(1) and E(2) in humans.
 

Such_Saturation

Member
Thread starter
Joined
Nov 26, 2013
Messages
7,367
Hello! Please skip the basics.

Unfortunately my lab doesn't check saturation but transferrin and ferritin are perfectly normal. Iron is slightly on the low side, just like hemoglobin and red blood cell count; that was the confusing part!

The only zinc I can find has silica in it... I took it yesterday and it made my dose of liver effective against acne once again. I was starting to get a couple new pimples despite my large weekly slice (at one point I had canker sores from the retinol). I can't buy oysters without a car, and I'm on suspended license.

This week I shall go T3 only and see what happens. But I am starting to doubt the potency of Cynomel. The only times it has worked is when I could feel some sort of an electrical sensation where the pill touched my tongue.

p.s. my half life calculation makes no sense. I don't know what impact the milk could be having.
 

staytuned

Member
Joined
Jan 2, 2014
Messages
49
Such_Saturation said:
Hello! Please skip the basics.

Unfortunately my lab doesn't check saturation but transferrin and ferritin are perfectly normal. Iron is slightly on the low side, just like hemoglobin and red blood cell count; that was the confusing part!

The only zinc I can find has silica in it... I took it yesterday and it made my dose of liver effective against acne once again. I was starting to get a couple new pimples despite my large weekly slice (at one point I had canker sores from the retinol). I can't buy oysters without a car, and I'm on suspended license.

This week I shall go T3 only and see what happens. But I am starting to doubt the potency of Cynomel. The only times it has worked is when I could feel some sort of an electrical sensation where the pill touched my tongue.

p.s. my half life calculation makes no sense. I don't know what impact the milk could be having.

Any luck w/the estradiol? I'm facing something similar (although different medical history) and am wondering if you had any luck w/moderating estrogen/estradiol?
 

Such_Saturation

Member
Thread starter
Joined
Nov 26, 2013
Messages
7,367
Unfortunately I haven't hit the lab for a while :D I am feeling better, though. I might check some levels this summer!
 
Joined
Feb 4, 2015
Messages
1,972
Such_Saturation said:
https://raypeatforum.com/forums/posts/34144/ Hello forum,

I have encountered, recently, high levels of Estradiol and low levels of Estrone in my blood for a male individual (43 pg/mL and 22 pg/ml, respectively). I have not been taking Pregnenolone or Progesterone recently. Do you have any suggestion regarding the cause of this? I'd say the pattern suggests the testosterone pathway is involved, but I'm not ready to rule out milk. Two quarts could give about 1500-2000 pg of Estradiol a day, resulting in a daily excess of 500 pg given a half life of 15 hours; over a month that would already be significant in my opinion (3 pg/mL of blood). Estrone should also be high, though.


I have also found late Cytomegalovirus, Zoster and Adenovirus antibodies; would you say it is a good idea to take some amount of Astragalus or Arabinogalactans to overstimulate the immune system? I know this be would hard on the body, as well as anti-Peat. C-reactive protein is very low (0.03mg/dL)

I am 22 and I have a history of mild anemia, neutropaenia, Tourette's like tics (triggered by feeding especially), candida, acne, gray patches and fatigue (gone). My diet consists of two quarts of pastured milk, juice, organ meats and seafood with T3 and T4. I have been stone cold lately! Do help me out, please.

Thank you, and be well.

What organ meats do you eat? Kidneys are a good source of selenium.
 
Last edited by a moderator:

Such_Saturation

Member
Thread starter
Joined
Nov 26, 2013
Messages
7,367
Westside PUFAs said:
What organ meats do you eat? Kidneys are a good source of selenium.

Only calf liver!
 
Similar threads
Thread starter Title Forum Replies Date
Cecilia L. High Pregnenolone, High Progesterone, High Estradiol, Low D Female Issues 13
C Obese, Low Estradiol And High Progesterone? Blood Work, Labs 7
I Hack My Labs: Lowish T, Very Low Estradiol, High Evening Cortisol Blood Work, Labs 14
Advocate2021 High Cholesterol and High Thyroid on Bloodwork- Confused Blood Work, Labs 15
N Do you need extra calcium with high dose k2? K 2
N Extremely High Cortisol Ask For Help or Advice 3
youngsinatra High Dose Niacinamide Self-Experiment. Experiments 20
haidut Heart attack survivors have high stress (cortisol/adrenaline) hypersensitivity, low androgens Scientific Studies 2
M High testosterone low libido Diet 10
J Levo gives me high BP- is anyone using small doses of T3 with meals in lieu of levo? Supplements, Pharmaceutical Drugs 2
Hgreen56 Is this how high dopamine personality looks like? Health 3
J High Saturated Fat/Cholesterol Causes Clogged Pores/Sebaceous Filaments Skin 7
Lokzo Cyproheptadine Prevents High Altitude-Induced Testicular Disturbances Scientific Studies 0
Bogdar Low PTH, Low D, High Calcium - How Is It Possible? Blood Work, Labs 12
Starship Is It Possible To Keep Metabolism High And MTOR Low? Metabolism 2
DANIEL A High Serotonin Society | Morning Routines, Self-Improvement, Habit Tracking Miscellaneous 1
Mito Effect Of High-Dose Omega-3 On Major Adverse Cardiovascular Events Polyunsaturated Fats, Seed Oils 0
U What's Worse High Fat No Starch Or Low Fat Higher Starch? Diet 12
2ManyHistamines After Years Of High Hemoglobin. Polycythemia Vera Diagnosis Blood Work, Labs 0
L High Volume Of Side Effects Expected With Cov-vax Miscellaneous Health Discussions 5
Hgreen56 Ray Peat (high Sugar) Diet Works Only Temporarily (?) Diet 0
forterpride Mothers PTH Level Is High Ask For Help or Advice 1
Hirri High Prolactin Question Thyroid and Hormones 6
H How To Lower High Prolactin? Blood Work, Labs 13
haidut Low, Not High, Metabolism Creates Oxidative Stress Scientific Studies 2
N Phosphatidylserine Gives Me Weird Feeling In My Kidney (High Cortisol) Cortisol, Serotonin, Histamine 1
S Hypoparathyroid And High Blood Calcium? Blood Work, Labs 4
johnwester130 Lamb Lungs Surprisingly High In Glycine Meat, Organ Meat, Gelatin, Seafood 5
M Any Long Term High Sugar Consumers Here? Discussing Dietary Models 28
D High Pulse, Low Morning Temperature Ask For Help or Advice 33
Hgreen56 Are White Potatoes High In Oxalate? Diet 8
M HTMA Results Help (Toxic Ratios High) Labs 3
ursidae Environment For High Cortisol Individuals Ask For Help or Advice 3
J Starch And High "manic" Libido Male Issues 19
CHEESEHEAD69 Blood Work. High AST & ALT Levels? Liver Damage? Blood Work, Labs 15
Sscobalt High Carb Moderate Protein Low Fat? Diet 37
C The Doc Said I Have High Cholesterol Cholesterol 12
A High Dosage Supplements, Pharmaceutical Drugs 0
Hgreen56 Has Anyone Ever Actually Heard Dr Peat Recommend A High Carb Diet? Diet 64
Razvan High TSH High T3 High T4 What Is This? Thyroid and Hormones 1
A Some Dude Sounding High IQ Talking About Looksmaxxing On An Incel Forum Ask For Help or Advice 72
S Dr Paul Saladinos Blood Work (High T, Low TSH) Metabolism 10
Hans 5 Fundamentals To Have In Place For A High Libido Articles & Scientific Studies 17
D Is High Cortisol And Reverse T3 Making Me Hypothyroid? Blood Work, Labs 4
gately People Who've Lowered High Ferritin: What Benefits Did You Notice? Health 17
Hgreen56 Foods With High-Fructose Corn Syrup (HFCS) Contains More Kcal Than Mentioned On Label? Diet, Recipes 8
Porridge High TSH On T3 Monotherapy (WTF? ) Blood Work, Labs 21
U High Fat Quality Goat Milk Or Low Fat Store Milk? Diet 9
C High Fasted Morning Blood Sugar? Ask For Help or Advice 0
Kaktos Excessively High Iodine Levels. Help! Supplements, Pharmaceutical Drugs 3

Similar threads

Top