The protection of long chain polyunsaturated fatty acids by melatonin during nonenzymatic lipid peroxidation of rat liver microsomes - PubMed
The in vivo and in vitro effects of melatonin (N-acetyl-5-methoxytryptamine) on lipid peroxidation of long chain polyunsaturated fatty acids (PUFA) located in rat liver microsomes were determined. The effect of intraperitoneal administration of melatonin (10 mg/kg weight/24 hr) on ascorbate-Fe++...
pubmed.ncbi.nlm.nih.gov
This study says that 1.2mM of melatonin can fully stop peroxidation of long-chain pufa, but only particularly block LOX and COX pufa metabolism. High dose of melatonin with such antiserotonin drug like cypro or just with thyroid is very interesting to experiment with