Mauritio
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- Feb 26, 2018
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Live high:train low increases muscle buffer capacity and submaximal cycling efficiency - PubMed
Showing intermittent time in altitude around 3000m having benefits ,e.g. less oxygen consumption . So even just a few hours every day at high altitude can have a good effect.
Metabolic and work efficiencies during exercise in Andean natives - PubMed
10% less oxygen consumption through long term stay at approximately 4500m .
"Measurements of respiratory quotient indicated preferential use of carbohydrate as fuel for muscle work, which is also advantageous in hypoxia because it maximizes the yield of ATP per mol of O2 consumed. Finally, minimizing the cost of muscle work was also reflected in energetic efficiency as classically defined (power output per metabolic power input); this was evident at all work rates but was most pronounced at submaximal work rates (efficiency approximately 1.5 times higher than in lowlander athletes)
Nonhematological Mechanisms of Improved Sea-Level... : Medicine & Science in Sports & Exercise
"In an animal model, it has been reported that 25-30 d of simulated altitude exposure equivalent to 5000 m via hypobaria for 5-6 h·d−1 resulted in improved mitochondrial efficiency (49). Lukyanova claims that the mechanisms responsible for this improved efficiency are related to the ability to maintain high coupling of oxidative phosphorylation and synthesis achieved by an increase in number of mitochondria in the cells accompanied by a reduced cytochrome content possessing a higher activity, new kinetic properties of NADH oxidation allowing maintenance of key enzyme activity in conditions of high NADH reduction under hypoxia, and reducing the role of the less efficient succinate oxidase pathway."
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Less risk of hypertension and diabetes-anemia for population living at 2500m.
High-altitude living decreases the risk of heart disease: A major risk factor for development of heart disease, stroke and diabetes is lower in people that live at higher altitudes; this also applies to people with a family history of these diseases
The results were quite clear -- the higher the altitude, the less likely you were of developing Metabolic Syndrome. Interestingly, using information about the participants' family history, the researchers could also assess if those more prone to this health problem also saw these benefits. "We found our results were independent of the genetic background of the individuals,"
Showing intermittent time in altitude around 3000m having benefits ,e.g. less oxygen consumption . So even just a few hours every day at high altitude can have a good effect.
Metabolic and work efficiencies during exercise in Andean natives - PubMed
10% less oxygen consumption through long term stay at approximately 4500m .
"Measurements of respiratory quotient indicated preferential use of carbohydrate as fuel for muscle work, which is also advantageous in hypoxia because it maximizes the yield of ATP per mol of O2 consumed. Finally, minimizing the cost of muscle work was also reflected in energetic efficiency as classically defined (power output per metabolic power input); this was evident at all work rates but was most pronounced at submaximal work rates (efficiency approximately 1.5 times higher than in lowlander athletes)
Nonhematological Mechanisms of Improved Sea-Level... : Medicine & Science in Sports & Exercise
"In an animal model, it has been reported that 25-30 d of simulated altitude exposure equivalent to 5000 m via hypobaria for 5-6 h·d−1 resulted in improved mitochondrial efficiency (49). Lukyanova claims that the mechanisms responsible for this improved efficiency are related to the ability to maintain high coupling of oxidative phosphorylation and synthesis achieved by an increase in number of mitochondria in the cells accompanied by a reduced cytochrome content possessing a higher activity, new kinetic properties of NADH oxidation allowing maintenance of key enzyme activity in conditions of high NADH reduction under hypoxia, and reducing the role of the less efficient succinate oxidase pathway."
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Less risk of hypertension and diabetes-anemia for population living at 2500m.
High-altitude living decreases the risk of heart disease: A major risk factor for development of heart disease, stroke and diabetes is lower in people that live at higher altitudes; this also applies to people with a family history of these diseases
The results were quite clear -- the higher the altitude, the less likely you were of developing Metabolic Syndrome. Interestingly, using information about the participants' family history, the researchers could also assess if those more prone to this health problem also saw these benefits. "We found our results were independent of the genetic background of the individuals,"
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