Hello everyone!
To introduce myself quickly, my name is Jacqui and I've very recently found the amazing work of Ray Peat through Danny Roddy. As a biology student and one with many health issues, I've found his take on physiology and health fascinating. That being said, I'm having some analysis paralysis with all this new information and was hoping for some guidance with healing myself. Any help or pointers would be massively helpful!
Basic Info:
Female, 22 years old, 5'4
Grew up in North America (US till age 6, then Canada to present)
1/2 First Nations (Cree), 1/4 Polish, 1/4 Mixed Eastern European
Current weight: ~180 lbs (have not weighed myself in a while so this is approximated, and will likely not again just to keep my sanity)
Medical History:
Diagnosed depression at 16 (debilitating from age 17-19)
Was warned of being prediabetic at 17 by GP
"Diagnosed" PCOS at 18 (GP did not confirm with ultrasound, but said it was probable from hormone tests and a particularly painful episode of abdominal pain he decided was a cyst rupturing)
"Diagnosed" IBS at 18 (GP didn't test, just told me that's what I was likely suffering from)
Very High Cholesterol, Very High Triglycerides
Current Symptoms:
Last menstrual cycle in Feb 2013
Hair thinning for past 2 years
Onset insomnia
Acid reflux, nausea after eating
Depression
Abdominal fat accumulation
Lightheaded feeling when standing up after lying down, sitting, or crouching
Persistent dehydration regardless of how much water I drink
Feeling anxious or agitated without reason for a span of time, ranging from 15 minutes to a day in length for no apparent reason
Mucus production after eating almost any food
Labs:
(From Genova Diagnostics one month ago)
Thyroid:
Total Thyroxine (T4) = 68.2 nmol/L (low)
Thyroid Stimulating Hormone (TSH) = 2.20 mIU/L (high)
Free Thyroxine (FT4) = 13.0 pmol/L (normal)
Free T3 (FT3) = 2.96 pmol/L (low)
FT4 : FT3 Ratio = 4.4 (high)
Reverse T3 (rT3) = 0.24 pmol/mL (normal)
Thyroglobulin (TG) = 27.7 IU/mL (normal)
Peroxidase (TPO) = 266 IU/ml (very high)
Melatonin, Cortisol:
Salivary Melatonin:
Sample 1 (07:00-9:00): 2.4 pg/mL (range: 1.0-10.0)
Sample 2 (15:00-17:00): 1.4 pg/mL (range: 0.0 - 2.0)
Sample 3 (02:30-3:30): 2.4 pg/mL (range: 5.0-30.0)
Salivary Cortisol:
Sample 1 (Post Awakening): 13.4 nmol/L (range: 12-22)
Sample 2 (+4 - 5 Hours): 6.5 nmol/L (range: 5.0-9.0)
Sample 3 (+4 - 5 Hours): 4.3 nmol/L (range: 3.0-7.0)
Sample 4 (Prior to Sleep): 2.8 nmol/L (range: 1.0-3.0)
Total Daily Cortisol: 27.0 nmol/L (range: 21-41)
Salivary DHEA:
Sample 2 (am): 0.85 nmol/L (range: 0.4-1.47)
Sample 3 (pm): 0.52 nmol/L (range: 0.4-1.47)
DHEA Mean: 0.69 nmol/L (range: 0.4-1.47)
DHEA : Cortisol Ratio: 2.54 (2.0-6.0)
28 Day Female Hormone Panel: (Image of female hormone panel
Follicular Phase:
Sample 1: Progesterone = 27.6 pg/ml (Range: 10-100 pg/ml), Oestradiol = 1.7 (Range: 2-5 pg/ml)
Sample 2: Progesterone = 35.2 pg/ml (Range: 10-100 pg/ml), Oestradiol = 1.8 (Range: 2-5 pg/ml)
Sample 3: Progesterone = 17.5 pg/ml (Range: 10-100 pg/ml), Oestradiol = 1.4 (Range: 2-5 pg/ml)
Sample 4: Progesterone = 38.0 pg/ml (Range: 10-100 pg/ml), Oestradiol = 2.6 (Range: 2-5 pg/ml)
Ovulation Phase:
Sample 5 (Pre-Ovulation): Progesterone = 49.8 pg/ml (Range: 10-100 pg/ml), Oestradiol = 3.2 (Range: 5-14 pg/ml)
Sample 6 (Ovulation): Progesterone = 33.0 pg/ml (Range: 10-100 pg/ml), Oestradiol = 2.3 (Range: 2-7 pg/ml)
Luteal Phase (Surge):
Sample 7: Progesterone = 119.2 pg/ml (Range: 100-400 pg/ml), Oestradiol = 2.6 (Range: 4-7 pg/ml)
Sample 8: Progesterone = 55.9 pg/ml (Range: 100-400 pg/ml), Oestradiol = 1.8 (Range: 4-7 pg/ml)
Sample 9: Progesterone = 32.1 pg/ml (Range: 100-400 pg/ml), Oestradiol = 2.7 (Range: 4-7 pg/ml)
Sample 10: Progesterone = 71.6 pg/ml (Range: 100-400 pg/ml), Oestradiol = 2.6 (Range: 4-7 pg/ml)
Post Luteal Phase:
Sample 11: Progesterone = 176.8 pg/ml (Range: 10-100 pg/ml), Oestradiol = 2.8 (Range: 2-5 pg/ml)
Sample 12: Progesterone = 46.2 pg/ml (Range: 10-100 pg/ml), Oestradiol = 2.2 (Range: 2-5 pg/ml)
Distribution Analysis & Testosterone:
Luteal Progesterone Output: 361.6 pg/ml (Range: 500-1300 pg/ml)
Total Oestradiol Output: 27.7 pg/ml (Range: 35-70 pg/ml)
Progesterone:Oestradiol Ratio: 25.4 (Range: 10-40)
Testosterone (Female): 62.5 pg/ml (Range: 20-70 pg/ml)
Ovulation Phase Analysis:
Luteal Progesterone Surge Occurred on Day: 16
Length of Luteal Phase in Days: 17 (Optimal: 11 Days)
Oestradiol Pre-Ovulatory Peak Day: 12
Oestradiol Peak to Luteal Surge: 4 (Optimal 4 Days)
At the time being, I've begun supplementing with Relora Plus to support my adrenals, with Selenium for my thyroid, topical Magnesium, and Vitamin D3, C, and a Multivitamin by Thorne Research.
My diet is a Paleo approach with the majority of my calories coming from fats, a moderate amount of carbs and a low amount of protein.
Any help is really appreciated!
To introduce myself quickly, my name is Jacqui and I've very recently found the amazing work of Ray Peat through Danny Roddy. As a biology student and one with many health issues, I've found his take on physiology and health fascinating. That being said, I'm having some analysis paralysis with all this new information and was hoping for some guidance with healing myself. Any help or pointers would be massively helpful!
Basic Info:
Female, 22 years old, 5'4
Grew up in North America (US till age 6, then Canada to present)
1/2 First Nations (Cree), 1/4 Polish, 1/4 Mixed Eastern European
Current weight: ~180 lbs (have not weighed myself in a while so this is approximated, and will likely not again just to keep my sanity)
Medical History:
Diagnosed depression at 16 (debilitating from age 17-19)
Was warned of being prediabetic at 17 by GP
"Diagnosed" PCOS at 18 (GP did not confirm with ultrasound, but said it was probable from hormone tests and a particularly painful episode of abdominal pain he decided was a cyst rupturing)
"Diagnosed" IBS at 18 (GP didn't test, just told me that's what I was likely suffering from)
Very High Cholesterol, Very High Triglycerides
Current Symptoms:
Last menstrual cycle in Feb 2013
Hair thinning for past 2 years
Onset insomnia
Acid reflux, nausea after eating
Depression
Abdominal fat accumulation
Lightheaded feeling when standing up after lying down, sitting, or crouching
Persistent dehydration regardless of how much water I drink
Feeling anxious or agitated without reason for a span of time, ranging from 15 minutes to a day in length for no apparent reason
Mucus production after eating almost any food
Labs:
(From Genova Diagnostics one month ago)
Thyroid:
Total Thyroxine (T4) = 68.2 nmol/L (low)
Thyroid Stimulating Hormone (TSH) = 2.20 mIU/L (high)
Free Thyroxine (FT4) = 13.0 pmol/L (normal)
Free T3 (FT3) = 2.96 pmol/L (low)
FT4 : FT3 Ratio = 4.4 (high)
Reverse T3 (rT3) = 0.24 pmol/mL (normal)
Thyroglobulin (TG) = 27.7 IU/mL (normal)
Peroxidase (TPO) = 266 IU/ml (very high)
Melatonin, Cortisol:
Salivary Melatonin:
Sample 1 (07:00-9:00): 2.4 pg/mL (range: 1.0-10.0)
Sample 2 (15:00-17:00): 1.4 pg/mL (range: 0.0 - 2.0)
Sample 3 (02:30-3:30): 2.4 pg/mL (range: 5.0-30.0)
Salivary Cortisol:
Sample 1 (Post Awakening): 13.4 nmol/L (range: 12-22)
Sample 2 (+4 - 5 Hours): 6.5 nmol/L (range: 5.0-9.0)
Sample 3 (+4 - 5 Hours): 4.3 nmol/L (range: 3.0-7.0)
Sample 4 (Prior to Sleep): 2.8 nmol/L (range: 1.0-3.0)
Total Daily Cortisol: 27.0 nmol/L (range: 21-41)
Salivary DHEA:
Sample 2 (am): 0.85 nmol/L (range: 0.4-1.47)
Sample 3 (pm): 0.52 nmol/L (range: 0.4-1.47)
DHEA Mean: 0.69 nmol/L (range: 0.4-1.47)
DHEA : Cortisol Ratio: 2.54 (2.0-6.0)
28 Day Female Hormone Panel: (Image of female hormone panel
Follicular Phase:
Sample 1: Progesterone = 27.6 pg/ml (Range: 10-100 pg/ml), Oestradiol = 1.7 (Range: 2-5 pg/ml)
Sample 2: Progesterone = 35.2 pg/ml (Range: 10-100 pg/ml), Oestradiol = 1.8 (Range: 2-5 pg/ml)
Sample 3: Progesterone = 17.5 pg/ml (Range: 10-100 pg/ml), Oestradiol = 1.4 (Range: 2-5 pg/ml)
Sample 4: Progesterone = 38.0 pg/ml (Range: 10-100 pg/ml), Oestradiol = 2.6 (Range: 2-5 pg/ml)
Ovulation Phase:
Sample 5 (Pre-Ovulation): Progesterone = 49.8 pg/ml (Range: 10-100 pg/ml), Oestradiol = 3.2 (Range: 5-14 pg/ml)
Sample 6 (Ovulation): Progesterone = 33.0 pg/ml (Range: 10-100 pg/ml), Oestradiol = 2.3 (Range: 2-7 pg/ml)
Luteal Phase (Surge):
Sample 7: Progesterone = 119.2 pg/ml (Range: 100-400 pg/ml), Oestradiol = 2.6 (Range: 4-7 pg/ml)
Sample 8: Progesterone = 55.9 pg/ml (Range: 100-400 pg/ml), Oestradiol = 1.8 (Range: 4-7 pg/ml)
Sample 9: Progesterone = 32.1 pg/ml (Range: 100-400 pg/ml), Oestradiol = 2.7 (Range: 4-7 pg/ml)
Sample 10: Progesterone = 71.6 pg/ml (Range: 100-400 pg/ml), Oestradiol = 2.6 (Range: 4-7 pg/ml)
Post Luteal Phase:
Sample 11: Progesterone = 176.8 pg/ml (Range: 10-100 pg/ml), Oestradiol = 2.8 (Range: 2-5 pg/ml)
Sample 12: Progesterone = 46.2 pg/ml (Range: 10-100 pg/ml), Oestradiol = 2.2 (Range: 2-5 pg/ml)
Distribution Analysis & Testosterone:
Luteal Progesterone Output: 361.6 pg/ml (Range: 500-1300 pg/ml)
Total Oestradiol Output: 27.7 pg/ml (Range: 35-70 pg/ml)
Progesterone:Oestradiol Ratio: 25.4 (Range: 10-40)
Testosterone (Female): 62.5 pg/ml (Range: 20-70 pg/ml)
Ovulation Phase Analysis:
Luteal Progesterone Surge Occurred on Day: 16
Length of Luteal Phase in Days: 17 (Optimal: 11 Days)
Oestradiol Pre-Ovulatory Peak Day: 12
Oestradiol Peak to Luteal Surge: 4 (Optimal 4 Days)
At the time being, I've begun supplementing with Relora Plus to support my adrenals, with Selenium for my thyroid, topical Magnesium, and Vitamin D3, C, and a Multivitamin by Thorne Research.
My diet is a Paleo approach with the majority of my calories coming from fats, a moderate amount of carbs and a low amount of protein.
Any help is really appreciated!