Help with DUTCH results- low estrogen, low progesterone but normal cortisol?

Joined
Dec 3, 2020
Messages
202
Location
UK
I recently received my DUTCH (Dried Urine Test for Comprehensive Hormones) results and I really did not expect what showed up and am confused on how to interpret them. Even the lab/provider are stumped... I have all the symptoms of high estrogen and high or irregular cortisol production but my results show

Progesterone metabolites are below luteal range (b and a- pregnanediol)
Estrogens are ALL low (estrone, estradiol and estriol and total estrogen)
Low DHEA-S and cortisol metabolites, preference for cortisone metabolites
Normal daily free cortisol and cortisone following a natural rise and fall


The one that is stumping me the most.... HIGH 5a- and 5b- androstanediol but LOW 5α-reductase activity and a preference for 5ß pathway

I have pretty bad cystic acne, irregular and anovulatory periods, sleep problems and fatigue (tired and wired), and diagnosed PCOS. I have read @haidut posts showing research supports estrogen as the cause of these issues not androgens so is this a case of high estrogens in the tissues and needing to supplement progesterone? I tried supplementing progesterone before and caused these symptoms to worsen, especially the acne and I hypothesized this was progesterone converting to cortisol.

How can I have low 5α-reductase activity but high 5a-androstanediol? Is this forming from DHEA metabolism? But then why is my Androsterone level normal?

I am no expert and probably missing some fundamental (maybe even simple) principles here. Any advice or info would be very much appreciated!
 

PaRa

Member
Joined
Nov 18, 2019
Messages
356
you may have too high prolactin ?

you're a men or a women ?

estrogen gets a heavy bad rap here but low estrogen is a real issue, low progesterone or high prolactin may be what cause the "too high estrogen issue"
 
K

Kaur Singh

Guest
How your pulse and temperature through out the day?
How is your progesterone in relation to estrogen?
how about cholesterol levels?
 

Similar threads

Back
Top Bottom