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Gonadin - Liquid Steroid Optimizer For Lab/R&D

Discussion in 'IdeaLabs' started by haidut, Feb 17, 2017.

  1. brix

    brix Member

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    I didn’t notice these when taking the full dose 1x daily.
     
  2. BlackSkull

    BlackSkull Member

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    Greetings,

    Salutations @haidut, your reputation precedes you.

    Subject shows signs of liking Gonadin

    Gonadin creates assertiveness.

    Gonadin makes subject stronger, especially combined with Andro with fuller, but leaner muscles, suggesting increased androgen receptor activity.

    Gonadin increases hair growth all over.

    Gonadin causes pimples and oily skin/hair.

    Gonadin or Andro + Gonadin makes females approach subject and find ways to have sex with subject.

    However, Gonadin or Andro + Gonadin decreases subjects libido and erection hardness, which is unusual for DHT.

    Gonadin also causes subject slight thinking delays; not as sharp or agile on it. More meatheadish.

    Also, finding the right balance between dosage and diet is hard for subject and results in stress responses or hyperstimulation, which can cause akward social interactions.

    Subject tried high carb/sugar diet, but found this only helps at dosing times. Subject will next try high fat diet with carbs/sugar only at dosing.

    Therefore, 1-2 drops of each is plenty after tissue saturation. However, fat loss is best at full dosages, but subject has inverse relationship with brain functioning.

    Subject uses it sublingually, orally, and topically for no more than 4 drops.
     
  3. vulture

    vulture Member

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    How does androsterone on its own affect your erection?
     
  4. OP
    haidut

    haidut Member

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    Thanks for the great feedback! The mental slowdown is likely due to both phytol and androsterone being GABA agonists. I don't think androsterone on its own would reduce erections, it is probably a matter of dosage and mixing the two. Most people report positive results with 2-3 drops andro daily, which you seemed to experience as well.
     
  5. BlackSkull

    BlackSkull Member

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    Sorry. To clarify, DHT is supposedly known as a compound that boosts libido and erection quality.

    However, subject cannot provide evidence to your question.

    Subject did not entertain that idea, because all other exogenous DHT compounds (including other andros) have had the same results.

    This may be individual reactions though.

    Only compounds that maximize endogenous hormone production has ever had a positive effect on subjects libido and erection quality.

    However, subject has never been exposed to Viagra type compounds either.
     
  6. OP
    haidut

    haidut Member

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    Maybe subject is one of the few blessed with naturally low estrogen levels and 5-AR steroids reduced estrogen even further and cause ED issues. DHT is a very potent steroid and most people who use it (ab)use massive amounts. A single daily dose of 5mg is probably enough even for subjects with high estrogen, yet most gels are formulated as to provide at least 15mg daily, and the synthetic DHT derivatives sold as oral formulations commonly come in 25mg pills. At hose doses, most strong androgens can produce endogenous androgen synthesis suppression, as well as estrogen suppression, and thus affect libido/ED.
     
  7. BlackSkull

    BlackSkull Member

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    Np. Thanks for the great products!

    What do you hypothesize one could add to counteract the slowdown, yet give the subject the positive benefits of all compounds?

    As to the andro solo aspect, I suspect, based solely on subject’s reactions to various compounds, that the key to quality libido and erections isnt as much the andro as it is the androgens inhibiting aromatase just enough to keep some estrogen and a plethra of androgens.

    Further, I suspect the true key to quality erections is more about timing e.g. arousal occurs at the precise time testosterone is converting into DHT.

    Furthermore, it may be a complexity of issues affecting overall systems functioning i.e not being well fed.

    However, one certainty is that when subject’s estrogen drops too low it is always associated with low vitality, which manifests as low sex drive and performance. Contrarily, this also occurs if estrogen is too high.

    Therefore, my current prognosis is in line with @haidut, which is to use full doses of Gonadin with just enough Andro to exude it’s positive effects without crashing estrogen.
     
  8. OP
    haidut

    haidut Member

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    Pregnenolone has been shown in studies to counteract the sedative effects of alcohol, benzodiazepines, and also promote wakefullness and improve reaction time and memory. Maybe this is the reason a lot of people like to stack Pansterone with andro or Pansterone with Gonadin.
     
  9. BlackSkull

    BlackSkull Member

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    Brilliant! I’ll have to give it a go then m8! Thanks!
     
  10. Wagner83

    Wagner83 Member

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  11. Jmejia16

    Jmejia16 New Member

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    I have male 28 yr lab rats . would you recommend me trying gonadin , Pansetone , Androsterone at once? I felt I always suffered of slightly low dht levels. I am trying to boost dht, without causing suppression or shutdown of my lab rats.
     
  12. OP
    haidut

    haidut Member

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    Pansterone and Gonadin would be what I'd try first. They should not cause suppression.
     
  13. Sajid

    Sajid Member

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    Guys is there a change in the formulation of gonadin?
     
  14. OP
    haidut

    haidut Member

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    What do you mean by that?
     
  15. Sajid

    Sajid Member

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    Squalene has been removed and something called 7 keto cholesterol is there
     
  16. Sajid

    Sajid Member

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    Squalene has been removed and looks like 7 keto cholesterol is added. Just checked the main page
     
  17. OP
    haidut

    haidut Member

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    Yes, we did one batch with 7-keto cholesterol, which has been shown to inhibit cortisol synthesis. Squalene was reported to cause acne and we wanted to replace it. The 7-keto cholesterol is probably also going away and will be replaced by another saturated fatty acid.
     
  18. Douglas Ek

    Douglas Ek Member

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    if you google 7-keto cholesterol there's all talk about it causing atherosclerotic plaque?
    also increasing amyloid beta increasing risk Alzheimers and lowering production of bile acid. There's also no notes on your website that the product has changed from squalene to 7-ketocholesterol so people who buy the product expect squalene. Also on the first page of this thread, there are only studies about squalene and none about 7-ketocholesterol. Which would further make people believe the product contain squalene even though it does not. Why did you add 7-ketocholesterol? I can't find anything positive about it. I've just received the product today and I'm quite dissapointed at the moment.
     
  19. OP
    haidut

    haidut Member

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    There are all observational studies, related to the theory of cholesterol causing CVD. 7-ketocholesterol is a potent inhibitor of cortisol synthesis similar to (but much more potent) than 7-keto DHEA. See below.
    https://www.ncbi.nlm.nih.gov/pubmed/18755798

    Again, some studies about it claim association between it and CVD but those studies are all observational and intervention studies administering 7-keto cholesterol did not find any negative effects. Here is one such study, which suggests that just like regular cholesterol, the 7-keto version is likely just a bystander and not a cause of CVD.
    Dietary cholesterol-oxidation products accumulate in serum and liver in apolipoprotein E-deficient mice, but do not accelerate atherosclerosis. - PubMed - NCBI

    Also, the amount we put in the supplement (5mg) is tiny and only enough to inhibit cortisol synthesis. In contrast, the amounts needed to match the observational studies for CVD are in the hundreds of milligrams daily. The second study above actually used the HED of hundreds of milligrams daily and still did not find negative effects. So, I highly doubt the 5mg per dose would do anything except affect the activity of 11b-HSD1 and thus lower cortisol levels.
     
  20. Douglas Ek

    Douglas Ek Member

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    Ok thank you for elaborating on this. Appreciate it
     
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