Gluconic Acid - Any Opinions On It As A Supp?


Sep 24, 2016
The salts of gluconic acid like Magnesium-Gluconate or Ca-Gluconate have interesting bioavailability-data and are cost efficient in compariosn to some other compounds. Now, you'd still intake substantial amountscof gluconic acid if you were to supp with these salts.

It's and acid fromed from Peat-favourite Glucose, it is found in some foods but s also produced by microbiota. It certainly has physiological actions and I'd like to figure out if supplementing it bears long-term hazards. It apparently is also an effective chelating-agent, which complicates matters even further in predicting how it would act as a supp like Mg-gluconate.

Gluconic acid - Wikipedia
Gluconic acid is an organic compound with molecular formula C6H12O7 and condensed structural formula HOCH2(CHOH)4COOH. It is one of the 16 stereoisomers of 2,3,4,5,6-pentahydroxyhexanoic acid.

In aqueous solution at neutral pH, gluconic acid forms the gluconate ion. The salts of gluconic acid are known as "gluconates". Gluconic acid, gluconate salts, and gluconate esters occur widely in nature because such species arise from the oxidation of glucose. Some drugs are injected in the form of gluconates.

Occurrence and uses
Gluconic acid occurs naturally in fruit, honey, and wine. In 1929 Horace Terhune Herrick developed a process for producing the salt by fermentation.[3] As a food additive (E574[4]), it is now known as an acidity regulator.

The gluconate anion chelates Ca2+, Fe2+, Al3+, and other metals, including lanthanides and actinides. It is also used in cleaning products, where it dissolves mineral deposits, especially in alkaline solution.

Calcium gluconate, in the form of a gel, is used to treat burns from hydrofluoric acid;[5][6] calcium gluconate injections may be used for more severe cases to avoid necrosis of deep tissues, as well as to treat hypocalcemia in hospitalized patients. Gluconate is also an electrolyte present in certain solutions, such as "plasmalyte a", used for intravenous fluid resuscitation.[7] Quinine gluconate is a salt of gluconic acid and quinine, which is used for intramuscular injection in the treatment of malaria.

Zinc gluconate injections are used to neuter male dogs.[8]

Ferrous gluconate injections have been proposed in the past to treat anemia.[9]

Gluconate is used as a concrete admixture (retarder) to slow down the cement hydration reactions and to delay the cement setting time. It allows so a longer time to place the concrete or to spread the cement hydration heat on a longer period of time to avoid too high temperature and the resulting cracks.[10][11] Retarders are mixed to concrete when the weather temperature is high or to cast large and thick concrete slabs in successive and sufficiently well mixed layers.

Gluconic acid

Gluconic Acid is the carboxylic acid formed by the oxidation of the first carbon of glucose with antiseptic and chelating properties. Gluconic acid, found abundantly in plant, honey and wine, can be prepared by fungal fermentation process commercially. This agent and its derivatives can used in formulation of pharmaceuticals, cosmetics and food products as additive or buffer salts. Aqueous gluconic acid solution contains cyclic ester glucono delta lactone structure, which chelates metal ions and forms very stable complexes. In alkaline solution, this agent exhibits strong chelating activities towards anions, i.e. calcium, iron, aluminium, copper, and other heavy metals.


Sep 15, 2013
I'm currently wondering if this could have any negative effects as well. Might be one for Peat himself.
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