Glaucoma? Anybody Treating Theirs, Anyone Doing Home Tonometry?

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A close relative has acute angle glaucoma. I would like to have her get a tonometer at home and see what causes the pressures to go up or down. She has had an iridotomy but still has high pressure in one eye. I feel that with a good feedback loop, we can figure this out.
 

Wilfrid

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Hi,
Do you know if your relative is easily prone to allergies as well?
Has she been already tested for helicobacter pylori infection?
 
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SQu

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My husband has what the specialist jokingly called 1/4 glaucoma. High IOP in one eye, no optic nerve damage. A month of trusopt eye drops, a carbonic anhydrase inhibitor I know little else about has normalized the IOP which was in the eye with a pterygium (I suspect that is not a coincidence). It was the only eye drop I liked the sound of (compared with the usual beta blockers/prostaglandins/alpha adrenergics). I think niacinamide may be helping protect the nerve and I think stress has been the cause of the IOP. We first tried acetazolamide orally but he didn't feel too good on it. I believe the tonometry is very fluctuating like blood pressure readings. Be interested to hear how that approach goes for her. Does she eat liver?
 

ecstatichamster

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My husband has what the specialist jokingly called 1/4 glaucoma. High IOP in one eye, no optic nerve damage. A month of trusopt eye drops, a carbonic anhydrase inhibitor I know little else about has normalized the IOP which was in the eye with a pterygium (I suspect that is not a coincidence). It was the only eye drop I liked the sound of (compared with the usual beta blockers/prostaglandins/alpha adrenergics). I think niacinamide may be helping protect the nerve and I think stress has been the cause of the IOP. We first tried acetazolamide orally but he didn't feel too good on it. I believe the tonometry is very fluctuating like blood pressure readings. Be interested to hear how that approach goes for her. Does she eat liver?

No she does not eat liver. Is he doing topical niacinamide or oral
 

SQu

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tried both oral and some in sterile water in the eye itself. both seemed to help but we're just doing oral right now due to being too busy to make up drops daily. It was about 4% solution of B3 but that was perhaps rather on the strong side. slight transient stinging. i kind of hesitate to mention the drops as i think the hygiene/sterility issues are hard to control when you do it yourself. we had no problems but there's potential for them. liver too can be a problem but it's even worse not having it. by which i mean, finding fresh liver that is not offputting like the stale stuff. he has oysters too. i'm also thinking that eye comfort has something to do with IOP. he's had problems with dry eyes concurrently with the high IOP. So the liver and oysters help that. Just trying to work it out as we go along.
 

Wilfrid

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In the last paragraph of his article on Cataracts: water, energy, light, and aging, he mentioned it.
Also in the KMUD: Current trends in Nitric oxide, he answered few questions about it.
Giraffe has made a wonderful job when transcribing it.
Current Trends In Nitric Oxide, KMUD, 2015
 
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ecstatichamster

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Relative is doing well. We use the tonometer. It reads around 22-24 before using any drops. The drops dorzolamide (Trusopt) work well and lack side effects. The pressure drops down to 14 or so for several hours after the drops and slowly creeps back up.

I do like having the tonometer. It lets us establish what causes and effects there are. The eye doctor doesn't even know we have and use this. They all feel threatened by this. It was hard to buy it in the USA actually as it is not officially marketed to "the public".
 

ecstatichamster

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We are going to try a drop of metergoline and see if it works. Applied outside the eye.
 

Wagner83

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IOP as in intraoccular pressure? if yes, ive seen it correlated with PUFA status on here. i believe it was a thread by haidut
I've seen many different studies on some anti-serotonin chemicals lowering IOP, but also 5ht2-a (correct??) agonist* and dopamine receptor d1 antagonist and d2 agonist which also seemed to work. I may have read that the results didn't necessarily transfer from one species to an other, so that's worth keeping in mind.

Serotonin-2 receptor agonists as novel ocular hypotensive agents and their cellular and molecular mechanisms of action. - PubMed - NCBI
 

Spartan300

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Hi All, I've been using prostaglandin/beta-blocker drops for this problem for several years now but it hadn't been proving that effective and after asking for advice on here I added, agmatine, thiamine & biotin (carbonic anhydrase inhibitors).

My recent check at the hospital showed pressures were at 11 & 12 instead of the usual mid-twenties numbers.
I have been avoiding PUFA as much as possible but I still eat out etc but try to mitigate with some Vit E around the times that I do.
Only other caveat & this might be highly significant is that I have been making a point of applying pressure to block tear duct for 4 - 5 min after applying the medication drops. Before I was only doing this for a few seconds. Two benefits of doing this are enhanced therapeutic effects of the drops as they stay in the eye longer & supposedly less systemic absorption.

Hope this helps.
 
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