Flavonoids

DaveFoster

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Jul 23, 2015
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Portland, Oregon
"Flavonoids and polyphenols, like our own estrogens, suppress the detoxifying systems of the body."
- Natural Estrogens

So does this mean that supplementing bioflavonoids along with vitamin c produces estrogenic effects in the body?

Orange juice opposes estrogen, so do these flavonoids have mixed effects?
 

LucH

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Jul 17, 2015
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so do these flavonoids have mixed effects?
Too much of a good thing can be bad.
Polyphenols depress detox pathway using enyme P450. Let's say toxins can remain longer.
Polyphenols inhibit Cyp450 detox enzyme
http://www.hindawi.com/journals/omcl/2015/854015/

Reveratrol & Quercetin
All studies seem to agree that resveratrol, curcumin, quercetin and bioperine are potent inhibitors of CyP450.
CyP450 is well-known to be involved in drug metabolism (detox enzyme through liver), but also in …
So resveratrol and quercetin inhibit detox.
http://www.longecity.org/forum/topic/40417-resveratrol-curcumin-quercetin-bioperine/

Table Drugs & CyP450 interference
http://www.anaesthetist.com/physiol/basics/metabol/cyp/Findex.htm
 

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