Anyone here who has tried Exemestane / Aromasin? Apparently in bodybuilding circles, it is the "mildest" Aromatase inhibitor (AI), with the least side-effects.
It seems to be derived from the structure of the hormone 4-androstenedione.
I'm thinking of trying it before I try letrozole, which apparently is the "harshest" or strongest AI.
Any particular side-effects / effects to watch out for? What has been your experience?
Exemestane is basically the same in effects as DHT, androsterone, androstenedione, androstanedione, androstenetrione, etc. They are all steroid aromatase inhibitors and pretty comparable in effectiveness in about the same doses.
Action of endogenous steroid inhibitors of brain aromatase relative to fadrozole. - PubMed - NCBI
Keep in mind that even tiny doses of exemestane works really well and there is no need to ingest it in monster quantities like the bodybuilders do. In those circles a dose of 12.5mg is considered mild and good for every day use, but in reality exemestane works the same even in 2.5mg doses and in the low doses it has no side effects like suppression of libido. See the last study in the original post of this thread (it is about exemestane).
Androsterone - A Potent Steroidal Aromatase Inhibitor
So, 2.5mg for a week is all you need to lower estrogen and not get bad reactions.